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O25781

- G6PI_HELPY

UniProt

O25781 - G6PI_HELPY

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, HP_1166
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511Proton donor By similarity
Active sitei382 – 3821 By similarity
Active sitei510 – 5101 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHPY:HP1166-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:HP_1166
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 545545Glucose-6-phosphate isomeraseUniRule annotationPRO_0000180652Add
BLAST

Proteomic databases

PRIDEiO25781.

Interactioni

Protein-protein interaction databases

STRINGi85962.HP1166.

Structurei

3D structure databases

ProteinModelPortaliO25781.
SMRiO25781. Positions 2-542.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiRAHYVSN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O25781-1 [UniParc]FASTAAdd to Basket

« Hide

MLTQLKTYPK LLKHYEEIKE VHMRDWFFKD KERASRYFLQ FESLSLDYSK    50
NRLNDTTLKL LFELANDCSL KEKIEAMFKG EKINTTEKRA VLHTALRSLN 100
DTEILLDNME VLKSIRSVLK RMRAFSDSVR SGKRLGYTNQ VITDIVNIGI 150
GGSDLGALMV CTALKRYAHP RLKMHFVSNV DGTQILDVLE KLNPASTLFI 200
VASKTFSTQE TLTNALTARK WFVERSGDEK HIAKHFVAVS TNKEAVQQFG 250
IDEHNMFEFW DFVGGRYSLW SAIGLSIMIY LGKKNFNALL KGAYLMDEHF 300
RNAPFESNLP VLMGLIGVWY INFFQSKSHL IAPYDQYLRH FPKFIQQLDM 350
ESNGKRISKK GEIIPYDTCP VVWGDMGINA QHAFFQLLHQ GTHLIPIDFI 400
ASLDKKPNAK GHHEILFSNV LAQAQAFMKG KSYEEALGEL LFKGLDKDEA 450
KDLAHHRVFF GNRPSNILLL EKISPSNIGA LVALYEHKVF VQGVIWDINS 500
FDQWGVELGK ELAVPILQEL EGHKSNAYFD SSTKHLIELY KNYNQ 545
Length:545
Mass (Da):62,487
Last modified:January 1, 1998 - v1
Checksum:iBDC68D1625190236
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08211.1.
PIRiF64665.
RefSeqiNP_207957.1. NC_000915.1.
YP_006935082.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08211; AAD08211; HP_1166.
GeneIDi13870361.
899926.
KEGGiheo:C694_06020.
hpy:HP1166.
PATRICi20593683. VBIHelPyl33062_1220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08211.1 .
PIRi F64665.
RefSeqi NP_207957.1. NC_000915.1.
YP_006935082.1. NC_018939.1.

3D structure databases

ProteinModelPortali O25781.
SMRi O25781. Positions 2-542.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85962.HP1166.

Proteomic databases

PRIDEi O25781.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08211 ; AAD08211 ; HP_1166 .
GeneIDi 13870361.
899926.
KEGGi heo:C694_06020.
hpy:HP1166.
PATRICi 20593683. VBIHelPyl33062_1220.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi RAHYVSN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci HPY:HP1166-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiG6PI_HELPY
AccessioniPrimary (citable) accession number: O25781
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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