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Protein

Flavodoxin

Gene

fldA

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Low-potential electron donor to a number of redox enzymes.By similarity

Cofactori

FMNBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciHPY:HP1161-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flavodoxin
Gene namesi
Name:fldA
Ordered Locus Names:HP_1161
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 164164FlavodoxinPRO_0000171634Add
BLAST

Proteomic databases

PaxDbiO25776.
PRIDEiO25776.

Interactioni

Protein-protein interaction databases

IntActiO25776. 1 interaction.
STRINGi85962.HP1161.

Structurei

Secondary structure

1
164
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 85Combined sources
Beta strandi11 – 133Combined sources
Helixi14 – 2613Combined sources
Beta strandi28 – 336Combined sources
Helixi34 – 363Combined sources
Helixi39 – 424Combined sources
Beta strandi46 – 5510Combined sources
Turni56 – 583Combined sources
Helixi62 – 687Combined sources
Helixi74 – 774Combined sources
Beta strandi79 – 868Combined sources
Turni89 – 913Combined sources
Turni96 – 983Combined sources
Helixi99 – 1079Combined sources
Beta strandi110 – 1123Combined sources
Beta strandi116 – 1183Combined sources
Beta strandi133 – 1397Combined sources
Turni141 – 1433Combined sources
Helixi145 – 1473Combined sources
Helixi148 – 15912Combined sources
Turni160 – 1623Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2BMVX-ray2.11A1-164[»]
2W5UX-ray2.62A/B1-164[»]
ProteinModelPortaliO25776.
SMRiO25776. Positions 2-164.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO25776.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 160157Flavodoxin-likePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the flavodoxin family.Curated
Contains 1 flavodoxin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105MHQ. Bacteria.
COG0716. LUCA.
KOiK03839.
OMAiASKGMAD.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR010086. Flavodoxin_lc.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
PIRSFiPIRSF038996. FldA. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01752. flav_long. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O25776-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIGIFFGT DSGNAEAIAE KISKAIGNAE VVDVAKASKE QFNSFTKVIL
60 70 80 90 100
VAPTAGAGDL QTDWEDFLGT LEASDFATKT IGLVGLGDQD TYSETFAEGI
110 120 130 140 150
FHIYEKAKAG KVVGQTPTDG YHFEASKAVE GGKFVGLVID EDNQDDLTDE
160
RISKWVEQVK GSFA
Length:164
Mass (Da):17,492
Last modified:January 1, 1998 - v1
Checksum:iEBAD44D97964608C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08207.1.
PIRiA64665.
RefSeqiNP_207952.1. NC_000915.1.
WP_000516078.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08207; AAD08207; HP_1161.
GeneIDi899921.
KEGGiheo:C694_05995.
hpy:HP1161.
PATRICi20593673. VBIHelPyl33062_1215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08207.1.
PIRiA64665.
RefSeqiNP_207952.1. NC_000915.1.
WP_000516078.1. NC_018939.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2BMVX-ray2.11A1-164[»]
2W5UX-ray2.62A/B1-164[»]
ProteinModelPortaliO25776.
SMRiO25776. Positions 2-164.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO25776. 1 interaction.
STRINGi85962.HP1161.

Proteomic databases

PaxDbiO25776.
PRIDEiO25776.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08207; AAD08207; HP_1161.
GeneIDi899921.
KEGGiheo:C694_05995.
hpy:HP1161.
PATRICi20593673. VBIHelPyl33062_1215.

Phylogenomic databases

eggNOGiENOG4105MHQ. Bacteria.
COG0716. LUCA.
KOiK03839.
OMAiASKGMAD.

Enzyme and pathway databases

BioCyciHPY:HP1161-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO25776.
PROiO25776.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR010086. Flavodoxin_lc.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
PIRSFiPIRSF038996. FldA. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01752. flav_long. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLAV_HELPY
AccessioniPrimary (citable) accession number: O25776
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.