ID   FLIW1_HELPY             Reviewed;         135 AA.
AC   O25769;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   27-MAR-2024, entry version 110.
DE   RecName: Full=Flagellar assembly factor FliW 1 {ECO:0000255|HAMAP-Rule:MF_01185};
GN   Name=fliW1 {ECO:0000255|HAMAP-Rule:MF_01185};
GN   OrderedLocusNames=HP_1154;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
RN   [2]
RP   BINDING TO FLAGELLIN.
RX   PubMed=11196647; DOI=10.1038/35051615;
RA   Rain J.-C., Selig L., De Reuse H., Battaglia V., Reverdy C., Simon S.,
RA   Lenzen G., Petel F., Wojcik J., Schaechter V., Chemama Y., Labigne A.,
RA   Legrain P.;
RT   "The protein-protein interaction map of Helicobacter pylori.";
RL   Nature 409:211-215(2001).
CC   -!- FUNCTION: Acts as an anti-CsrA protein, binds CsrA and prevents it from
CC       repressing translation of its target genes, one of which is flagellin.
CC       Binds to flagellin and participates in the assembly of the flagellum.
CC       {ECO:0000255|HAMAP-Rule:MF_01185}.
CC   -!- SUBUNIT: Interacts with translational regulator CsrA and flagellin(s).
CC       {ECO:0000255|HAMAP-Rule:MF_01185, ECO:0000269|PubMed:11196647}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01185}.
CC   -!- SIMILARITY: Belongs to the FliW family. {ECO:0000255|HAMAP-
CC       Rule:MF_01185, ECO:0000305}.
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DR   EMBL; AE000511; AAD08203.1; -; Genomic_DNA.
DR   PIR; B64664; B64664.
DR   RefSeq; NP_207945.1; NC_000915.1.
DR   RefSeq; WP_001105854.1; NC_018939.1.
DR   AlphaFoldDB; O25769; -.
DR   SMR; O25769; -.
DR   DIP; DIP-3307N; -.
DR   IntAct; O25769; 6.
DR   MINT; O25769; -.
DR   STRING; 85962.HP_1154; -.
DR   PaxDb; 85962-C694_05960; -.
DR   DNASU; 899914; -.
DR   EnsemblBacteria; AAD08203; AAD08203; HP_1154.
DR   KEGG; hpy:HP_1154; -.
DR   PATRIC; fig|85962.47.peg.1238; -.
DR   eggNOG; COG1699; Bacteria.
DR   InParanoid; O25769; -.
DR   OrthoDB; 5372942at2; -.
DR   PhylomeDB; O25769; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.290.10; BH3618-like; 1.
DR   HAMAP; MF_01185; FliW; 1.
DR   InterPro; IPR003775; Flagellar_assembly_factor_FliW.
DR   InterPro; IPR024046; Flagellar_assmbl_FliW_dom_sf.
DR   PANTHER; PTHR39190; FLAGELLAR ASSEMBLY FACTOR FLIW; 1.
DR   PANTHER; PTHR39190:SF1; FLAGELLAR ASSEMBLY FACTOR FLIW; 1.
DR   Pfam; PF02623; FliW; 1.
DR   SUPFAM; SSF141457; BH3618-like; 1.
PE   1: Evidence at protein level;
KW   Bacterial flagellum biogenesis; Chaperone; Cytoplasm; Reference proteome;
KW   Translation regulation.
FT   CHAIN           1..135
FT                   /note="Flagellar assembly factor FliW 1"
FT                   /id="PRO_0000272999"
SQ   SEQUENCE   135 AA;  15604 MW;  31D7A4E0A0D00D2D CRC64;
     MNYFLKAPIL GFEHINEVRL EKIDSLFSRL ISQTNSPMAL DMVLVNPYCL REYSFVIPKY
     IELLLELDSH SKVEVYCVVV LQKNLEDSMV NFLAPLVFNS KNGFGAQVAL SMMDYPDFGF
     RDPLKSFVIQ ERERA
//