O25769 (FLIW1_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flagellar assembly factor FliW 1

Gene names

Name:	fliW1
Ordered Locus Names:	HP_1154

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	135 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum By similarity. HAMAP-Rule MF_01185
Subunit structure	Interacts with flagellin.
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01185.
Sequence similarities	Belongs to the FliW family.

Ontologies

Keywords
Biological process	Bacterial flagellum biogenesis
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	flagellum assembly Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 135	135	Flagellar assembly factor FliW 1 HAMAP-Rule MF_01185		PRO_0000272999

Sequences

	Sequence		Length	Mass (Da)
	O25769 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 31D7A4E0A0D00D2D	FASTA	135	15,604
	10 20 30 40 50 60 MNYFLKAPIL GFEHINEVRL EKIDSLFSRL ISQTNSPMAL DMVLVNPYCL REYSFVIPKY 70 80 90 100 110 120 IELLLELDSH SKVEVYCVVV LQKNLEDSMV NFLAPLVFNS KNGFGAQVAL SMMDYPDFGF 130 RDPLKSFVIQ ERERA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.
[2]	"The protein-protein interaction map of Helicobacter pylori." Rain J.-C., Selig L., De Reuse H., Battaglia V., Reverdy C., Simon S., Lenzen G., Petel F., Wojcik J., Schaechter V., Chemama Y., Labigne A., Legrain P. Nature 409:211-215(2001) [PubMed] [Europe PMC] [Abstract] Cited for: BINDING TO FLAGELLIN.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08203.1.
PIR	B64664.
RefSeq	NP_207945.1. NC_000915.1. YP_006935070.1. NC_018939.1.
3D structure databases
ProteinModelPortal	O25769.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3307N.
MINT	MINT-169612.
STRING	85962.HP1154.
Protocols and materials databases
DNASU	899914.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD08203; AAD08203; HP_1154.
GeneID	13870349. 899914.
KEGG	heo:C694_05960. hpy:HP1154.
PATRIC	20593659. VBIHelPyl33062_1208.
Phylogenomic databases
eggNOG	COG1699.
OMA	PANACAL.
ProtClustDB	PRK13283.
Family and domain databases
Gene3D	2.30.290.10. 1 hit.
HAMAP	MF_01185. FliW.
InterPro	IPR003775. Flagellar_assembly_factor_FliW. IPR024046. Flagellar_assmbl_FliW_dom. [Graphical view]
Pfam	PF02623. FliW. 1 hit. [Graphical view]
SUPFAM	SSF141457. SSF141457. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FLIW1_HELPY

Accession

Primary (citable) accession number: O25769

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	January 1, 1998
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program