O25758 (PARB_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable chromosome-partitioning protein ParB

Gene names

Name:	parB
Ordered Locus Names:	HP_1138

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication By similarity.
Sequence similarities	Belongs to the ParB family.

Ontologies

Keywords
Biological process	Chromosome partition
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chromosome segregation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Probable chromosome-partitioning protein ParB		PRO_0000178682

Sequences

	Sequence		Length	Mass (Da)
	O25758 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: E12FE4F5E20826B8	FASTA	290	33,166
	10 20 30 40 50 60 MAKNKVLGRG LADIFPEINE VYEQGLYERA NRVVELGIDE VMPNPYQPRK VFSEDSLEEL 70 80 90 100 110 120 AQSIKEHGLL QPVLVVSENG RYHLIAGERR LRASKLAKMP TIKAIVVDIE QEKMREVALI 130 140 150 160 170 180 ENIQREDLNP LELARSYKEL LESYQMTQEE LSKIVKKSRA HVANIMRLLT LSSKVQNALL 190 200 210 220 230 240 EEKITSGHAK VLVGLDGEKQ ELILNSIIGQ KLSVRQTEDL ARDFKINANF DNKKHGFKQT 250 260 270 280 290 QTLIAGDELE RLNQSLWDHY KLKAALKGNK IVLRCYENSL LEAFMKKMMS

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08184.1.
PIR	B64662.
RefSeq	NP_207929.1. NC_000915.1. YP_006935054.1. NC_018939.1.
3D structure databases
ProteinModelPortal	O25758.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3152N.
MINT	MINT-185653.
STRING	85962.HP1138.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD08184; AAD08184; HP_1138.
GeneID	13870332. 899675.
KEGG	heo:C694_05870. hpy:HP1138.
PATRIC	20593621. VBIHelPyl33062_1190.
Phylogenomic databases
eggNOG	COG1475.
KO	K03497.
OMA	AFMKKMM.
ProtClustDB	CLSK551856.
Family and domain databases
InterPro	IPR004437. ParB_part. IPR003115. ParBc. [Graphical view]
Pfam	PF02195. ParBc. 1 hit. [Graphical view]
SMART	SM00470. ParB. 1 hit. [Graphical view]
SUPFAM	SSF110849. ParBc. 1 hit.
TIGRFAMs	TIGR00180. parB_part. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PARB_HELPY

Accession

Primary (citable) accession number: O25758

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	January 1, 1998
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program