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O25731

- GLK_HELPY

UniProt

O25731 - GLK_HELPY

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Protein
Glucokinase
Gene
glk, HP_1103
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 176ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP1103-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:HP_1103
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336GlucokinaseUniRule annotation
PRO_0000215128Add
BLAST

Proteomic databases

PRIDEiO25731.

Interactioni

Protein-protein interaction databases

STRINGi85962.HP1103.

Structurei

3D structure databases

ProteinModelPortaliO25731.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
KOiK00845.
OMAiDKAPHSA.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

O25731-1 [UniParc]FASTAAdd to Basket

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MPKTETYPRL LADIGGTNAR FGLEVAPRQI ECIEVLRCED FESLSDAVRF    50
YLSKCKESLK LHPIYGSFAV ATPIMGDFVQ MTNNHWTFSI ETTRQCLTLK 100
KLLVINDFVA QAYAISAMQE NDLAQIGGIK CEINAPKAIL GPGTGLGVST 150
LIQNSDGSLK VLPGEGGHVS FAPFDDLEIL VWQYARSKFN HVSAERFLSG 200
SGLVLIYEAL SKRKGLEKVA KLSKAELTPQ IISECALNGD YPICRLTLDT 250
FCSMLGTLAA DVALTLGARG GVYLCGGIIP RFIDYFKTSP FRARFETKGR 300
MGAFLASIPV HVVLKKTPGL DGAGIALENY LLHDKI 336
Length:336
Mass (Da):36,661
Last modified:January 1, 1998 - v1
Checksum:iBA804AB6040151D8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08146.1.
PIRiG64657.
RefSeqiNP_207894.1. NC_000915.1.
YP_006935018.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08146; AAD08146; HP_1103.
GeneIDi13870296.
899639.
KEGGiheo:C694_05690.
hpy:HP1103.
PATRICi20593545. VBIHelPyl33062_1152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08146.1 .
PIRi G64657.
RefSeqi NP_207894.1. NC_000915.1.
YP_006935018.1. NC_018939.1.

3D structure databases

ProteinModelPortali O25731.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85962.HP1103.

Proteomic databases

PRIDEi O25731.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08146 ; AAD08146 ; HP_1103 .
GeneIDi 13870296.
899639.
KEGGi heo:C694_05690.
hpy:HP1103.
PATRICi 20593545. VBIHelPyl33062_1152.

Phylogenomic databases

eggNOGi COG0837.
KOi K00845.
OMAi DKAPHSA.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci HPY:HP1103-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiGLK_HELPY
AccessioniPrimary (citable) accession number: O25731
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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