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O25730

- 6PGL_HELPY

UniProt

O25730 - 6PGL_HELPY

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Protein
6-phosphogluconolactonase
Gene
pgl, devB, HP_1102
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciHPY:HP1102-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:HP_1102
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2272276-phosphogluconolactonase
PRO_0000090095Add
BLAST

Proteomic databases

PRIDEiO25730.

Interactioni

Protein-protein interaction databases

DIPiDIP-3651N.
IntActiO25730. 3 interactions.
MINTiMINT-159493.
STRINGi85962.HP1102.

Structurei

3D structure databases

ProteinModelPortaliO25730.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
KOiK01057.
OMAiKTKERFQ.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

O25730-1 [UniParc]FASTAAdd to Basket

« Hide

MGYQLFEFEN LKDCHKALTE RFKEFFNTAL KKHHQISIAF SGGRSPISLL    50
QKLSVLNLKW HECLISLVDE RIIDTSHDDS NTKLLHDYLL QNNALKASFI 100
PLLPEKISSD TNALFNFANQ HFKQPHLAIL GMGTDGHTAS LFPETSAFLN 150
EEKENIVLTK PINAPYERLS MSVNALENCE KLFLSISGVE KRGVLEKALK 200
ENAPYSLPIA RILHSQKVTT EVFYAKN 227
Length:227
Mass (Da):25,728
Last modified:January 1, 1998 - v1
Checksum:iB2592B35B63971A6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08145.1.
PIRiF64657.
RefSeqiNP_207893.1. NC_000915.1.
YP_006935017.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08145; AAD08145; HP_1102.
GeneIDi13870295.
899638.
KEGGiheo:C694_05685.
hpy:HP1102.
PATRICi20593543. VBIHelPyl33062_1151.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD08145.1 .
PIRi F64657.
RefSeqi NP_207893.1. NC_000915.1.
YP_006935017.1. NC_018939.1.

3D structure databases

ProteinModelPortali O25730.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3651N.
IntActi O25730. 3 interactions.
MINTi MINT-159493.
STRINGi 85962.HP1102.

Proteomic databases

PRIDEi O25730.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08145 ; AAD08145 ; HP_1102 .
GeneIDi 13870295.
899638.
KEGGi heo:C694_05685.
hpy:HP1102.
PATRICi 20593543. VBIHelPyl33062_1151.

Phylogenomic databases

eggNOGi COG0363.
KOi K01057.
OMAi KTKERFQ.
OrthoDBi EOG63FW46.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci HPY:HP1102-MONOMER.

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry namei6PGL_HELPY
AccessioniPrimary (citable) accession number: O25730
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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