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O25730

- 6PGL_HELPY

UniProt

O25730 - 6PGL_HELPY

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciHPY:HP1102-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    Name:pgl
    Synonyms:devB
    Ordered Locus Names:HP_1102
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2272276-phosphogluconolactonasePRO_0000090095Add
    BLAST

    Proteomic databases

    PRIDEiO25730.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-3651N.
    IntActiO25730. 3 interactions.
    MINTiMINT-159493.
    STRINGi85962.HP1102.

    Structurei

    3D structure databases

    ProteinModelPortaliO25730.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    KOiK01057.
    OMAiKTKERFQ.
    OrthoDBiEOG63FW46.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O25730-1 [UniParc]FASTAAdd to Basket

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    MGYQLFEFEN LKDCHKALTE RFKEFFNTAL KKHHQISIAF SGGRSPISLL    50
    QKLSVLNLKW HECLISLVDE RIIDTSHDDS NTKLLHDYLL QNNALKASFI 100
    PLLPEKISSD TNALFNFANQ HFKQPHLAIL GMGTDGHTAS LFPETSAFLN 150
    EEKENIVLTK PINAPYERLS MSVNALENCE KLFLSISGVE KRGVLEKALK 200
    ENAPYSLPIA RILHSQKVTT EVFYAKN 227
    Length:227
    Mass (Da):25,728
    Last modified:January 1, 1998 - v1
    Checksum:iB2592B35B63971A6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08145.1.
    PIRiF64657.
    RefSeqiNP_207893.1. NC_000915.1.
    YP_006935017.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD08145; AAD08145; HP_1102.
    GeneIDi13870295.
    899638.
    KEGGiheo:C694_05685.
    hpy:HP1102.
    PATRICi20593543. VBIHelPyl33062_1151.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08145.1 .
    PIRi F64657.
    RefSeqi NP_207893.1. NC_000915.1.
    YP_006935017.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali O25730.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-3651N.
    IntActi O25730. 3 interactions.
    MINTi MINT-159493.
    STRINGi 85962.HP1102.

    Proteomic databases

    PRIDEi O25730.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD08145 ; AAD08145 ; HP_1102 .
    GeneIDi 13870295.
    899638.
    KEGGi heo:C694_05685.
    hpy:HP1102.
    PATRICi 20593543. VBIHelPyl33062_1151.

    Phylogenomic databases

    eggNOGi COG0363.
    KOi K01057.
    OMAi KTKERFQ.
    OrthoDBi EOG63FW46.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci HPY:HP1102-MONOMER.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry namei6PGL_HELPY
    AccessioniPrimary (citable) accession number: O25730
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3