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O25701 (TATC_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Sec-independent protein translocase protein TatC
Gene names
Name:tatC
Ordered Locus Names:HP_1061
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides By similarity. HAMAP-Rule MF_00902

Subunit structure

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00902.

Sequence similarities

Belongs to the TatC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Sec-independent protein translocase protein TatC HAMAP-Rule MF_00902
PRO_0000098087

Regions

Transmembrane18 – 3821Helical; Potential
Transmembrane69 – 8921Helical; Potential
Transmembrane96 – 11621Helical; Potential
Transmembrane151 – 17121Helical; Potential
Transmembrane187 – 20721Helical; Potential
Transmembrane208 – 22821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O25701 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 65F0D8D3251DA8CC

FASTA25328,226
        10         20         30         40         50         60 
MFEDLKPHLQ ELRKRLMVSV GTILVAFLGC FHFWKSIFEF VKNSYKGTLI QLSPIEGVMV 

        70         80         90        100        110        120 
AVKISFSAAI VISMPIIFWQ LWLFIAPGLY KNEKKVILPF VFFGSGMFLI GAAFSYYVVF 

       130        140        150        160        170        180 
PFIIEYLATF GSDVFAANIS ASSYVSFFTR LILGFGVAFE LPVLAYFLAK VGLITDASLK 

       190        200        210        220        230        240 
AYFKYAIVVI FIVAAIITPP DVVSQIFMAL PLVGLYGLSI LIAKMVNPAP KDNENNNENN 

       250 
NENNTKENTK SES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD08101.1.
PIRE64652.
RefSeqNP_207852.1. NC_000915.1.
YP_006934977.1. NC_018939.1.

3D structure databases

ProteinModelPortalO25701.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING85962.HP1061.

Proteomic databases

PRIDEO25701.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD08101; AAD08101; HP_1061.
GeneID13870254.
899596.
KEGGheo:C694_05485.
hpy:HP1061.
PATRIC20593459. VBIHelPyl33062_1110.

Phylogenomic databases

eggNOGCOG0805.
KOK03118.
OMAYLDFVLL.
OrthoDBEOG60SCQS.
ProtClustDBCLSK872350.

Enzyme and pathway databases

BioCycHPY:HP1061-MONOMER.

Family and domain databases

HAMAPMF_00902. TatC.
InterProIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamPF00902. TatC. 1 hit.
[Graphical view]
PRINTSPR01840. TATCFAMILY.
TIGRFAMsTIGR00945. tatC. 1 hit.
PROSITEPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTATC_HELPY
AccessionPrimary (citable) accession number: O25701
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names