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O25701

- TATC_HELPY

UniProt

O25701 - TATC_HELPY

Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

    GO - Molecular functioni

    1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. protein transport by the Tat complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Enzyme and pathway databases

    BioCyciHPY:HP1061-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sec-independent protein translocase protein TatCUniRule annotation
    Gene namesi
    Name:tatCUniRule annotation
    Ordered Locus Names:HP_1061
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of plasma membrane Source: UniProtKB-HAMAP
    2. TAT protein transport complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 253253Sec-independent protein translocase protein TatCPRO_0000098087Add
    BLAST

    Proteomic databases

    PRIDEiO25701.

    Interactioni

    Subunit structurei

    The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

    Protein-protein interaction databases

    STRINGi85962.HP1061.

    Structurei

    3D structure databases

    ProteinModelPortaliO25701.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei18 – 3821HelicalUniRule annotationAdd
    BLAST
    Transmembranei69 – 8921HelicalUniRule annotationAdd
    BLAST
    Transmembranei96 – 11621HelicalUniRule annotationAdd
    BLAST
    Transmembranei151 – 17121HelicalUniRule annotationAdd
    BLAST
    Transmembranei187 – 20721HelicalUniRule annotationAdd
    BLAST
    Transmembranei208 – 22821HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TatC family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0805.
    KOiK03118.
    OMAiYRNERRA.
    OrthoDBiEOG60SCQS.

    Family and domain databases

    HAMAPiMF_00902. TatC.
    InterProiIPR019820. Sec-indep_translocase_CS.
    IPR002033. TatC.
    [Graphical view]
    PfamiPF00902. TatC. 1 hit.
    [Graphical view]
    PRINTSiPR01840. TATCFAMILY.
    TIGRFAMsiTIGR00945. tatC. 1 hit.
    PROSITEiPS01218. TATC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O25701-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFEDLKPHLQ ELRKRLMVSV GTILVAFLGC FHFWKSIFEF VKNSYKGTLI    50
    QLSPIEGVMV AVKISFSAAI VISMPIIFWQ LWLFIAPGLY KNEKKVILPF 100
    VFFGSGMFLI GAAFSYYVVF PFIIEYLATF GSDVFAANIS ASSYVSFFTR 150
    LILGFGVAFE LPVLAYFLAK VGLITDASLK AYFKYAIVVI FIVAAIITPP 200
    DVVSQIFMAL PLVGLYGLSI LIAKMVNPAP KDNENNNENN NENNTKENTK 250
    SES 253
    Length:253
    Mass (Da):28,226
    Last modified:January 1, 1998 - v1
    Checksum:i65F0D8D3251DA8CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08101.1.
    PIRiE64652.
    RefSeqiNP_207852.1. NC_000915.1.
    YP_006934977.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD08101; AAD08101; HP_1061.
    GeneIDi13870254.
    899596.
    KEGGiheo:C694_05485.
    hpy:HP1061.
    PATRICi20593459. VBIHelPyl33062_1110.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD08101.1 .
    PIRi E64652.
    RefSeqi NP_207852.1. NC_000915.1.
    YP_006934977.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali O25701.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 85962.HP1061.

    Proteomic databases

    PRIDEi O25701.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD08101 ; AAD08101 ; HP_1061 .
    GeneIDi 13870254.
    899596.
    KEGGi heo:C694_05485.
    hpy:HP1061.
    PATRICi 20593459. VBIHelPyl33062_1110.

    Phylogenomic databases

    eggNOGi COG0805.
    KOi K03118.
    OMAi YRNERRA.
    OrthoDBi EOG60SCQS.

    Enzyme and pathway databases

    BioCyci HPY:HP1061-MONOMER.

    Family and domain databases

    HAMAPi MF_00902. TatC.
    InterProi IPR019820. Sec-indep_translocase_CS.
    IPR002033. TatC.
    [Graphical view ]
    Pfami PF00902. TatC. 1 hit.
    [Graphical view ]
    PRINTSi PR01840. TATCFAMILY.
    TIGRFAMsi TIGR00945. tatC. 1 hit.
    PROSITEi PS01218. TATC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiTATC_HELPY
    AccessioniPrimary (citable) accession number: O25701
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3