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O25610

- Y956_HELPY

UniProt

O25610 - Y956_HELPY

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Protein
Uncharacterized RNA pseudouridine synthase HP_0956
Gene
HP_0956
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

RNA uridine = RNA pseudouridine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931 By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. pseudouridine synthase activity Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciHPY:HP0956-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA pseudouridine synthase HP_0956 (EC:5.4.99.-)
Alternative name(s):
RNA pseudouridylate synthase
RNA-uridine isomerase
Gene namesi
Ordered Locus Names:HP_0956
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 242242Uncharacterized RNA pseudouridine synthase HP_0956
PRO_0000162737Add
BLAST

Proteomic databases

PRIDEiO25610.

PTM databases

PhosSiteiP11071051.

Interactioni

Protein-protein interaction databases

IntActiO25610. 2 interactions.
STRINGi85962.HP0956.

Structurei

3D structure databases

ProteinModelPortaliO25610.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 6261S4 RNA-binding
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0564.
KOiK06179.
OMAiYGDSQHS.
OrthoDBiEOG6P070X.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O25610-1 [UniParc]FASTAAdd to Basket

« Hide

MEKAYKILSV QENISHKKAK ALIDSGLVSI GGKKLMVARK ELPKNTHFSV    50
QKVEKPSVIF EDENILALFK PPFIESYDLA SFFKGWALLH RLDKETSGVV 100
LLVKENSEFH LKAKKAFKDR AVKKEYLALT QGIIEEEREI NAPILTFKTT 150
KAFSKISKKG QEAVTIITPL KIINKKTLLK VGIKTGRTHQ IRVHLKHINH 200
PIIGDTLYNN EPSLAKRLML HAHKIALLGY EFEAIAPKEF EI 242
Length:242
Mass (Da):27,457
Last modified:January 1, 1998 - v1
Checksum:iBB94C062C7BE8165
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07999.1.
PIRiD64639.
RefSeqiNP_207748.1. NC_000915.1.
YP_006934873.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07999; AAD07999; HP_0956.
GeneIDi13870149.
899489.
KEGGiheo:C694_04925.
hpy:HP0956.
PATRICi20593225. VBIHelPyl33062_0994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07999.1 .
PIRi D64639.
RefSeqi NP_207748.1. NC_000915.1.
YP_006934873.1. NC_018939.1.

3D structure databases

ProteinModelPortali O25610.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O25610. 2 interactions.
STRINGi 85962.HP0956.

PTM databases

PhosSitei P11071051.

Proteomic databases

PRIDEi O25610.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07999 ; AAD07999 ; HP_0956 .
GeneIDi 13870149.
899489.
KEGGi heo:C694_04925.
hpy:HP0956.
PATRICi 20593225. VBIHelPyl33062_0994.

Phylogenomic databases

eggNOGi COG0564.
KOi K06179.
OMAi YGDSQHS.
OrthoDBi EOG6P070X.

Enzyme and pathway databases

BioCyci HPY:HP0956-MONOMER.

Family and domain databases

InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view ]
Pfami PF00849. PseudoU_synth_2. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
PROSITEi PS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiY956_HELPY
AccessioniPrimary (citable) accession number: O25610
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi