O25578 (Y920_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein HP_0920

Gene names

Ordered Locus Names:

HP_0920

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the BI1 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	Uncharacterized protein HP_0920		PRO_0000179105
Regions
	Transmembrane	34 – 54	21	Helical; Potential
	Transmembrane	56 – 76	21	Helical; Potential
	Transmembrane	87 – 107	21	Helical; Potential
	Transmembrane	111 – 131	21	Helical; Potential
	Transmembrane	146 – 166	21	Helical; Potential
	Transmembrane	167 – 187	21	Helical; Potential
	Transmembrane	205 – 225	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	O25578 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: ABC25577614F5030	FASTA	230	25,141
	10 20 30 40 50 60 MALYDRANSR NAYAEDSLLR ESELVSFVKT TYKFFAGSLL LATIGALLGL MNFQAVVQYK 70 80 90 100 110 120 WVFFIAEIAA FFGLMFSKSK PGLNLFMLFA FTSLSGVTLV PLLGMVIAKA GLGAIWQALG 130 140 150 160 170 180 MTTIVFGLMS VYALKTKNDL ANMGKMLFIA LIVVVVCSLI NLFLGSPMFQ VVIAGASAIL 190 200 210 220 230 FSLYIAYDTQ NIVKGMYDSP IDAAVSLYLD FLNVFISILQ IIGIFSDRDT

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD07964.1.
PIR	H64634.
RefSeq	NP_207712.1. NC_000915.1. YP_006934835.1. NC_018939.1.
3D structure databases
ProteinModelPortal	O25578.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3284N.
MINT	MINT-186577.
STRING	85962.HP0920.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD07964; AAD07964; HP_0920.
GeneID	13870107. 899449.
KEGG	heo:C694_04735. hpy:HP0920.
PATRIC	20593141. VBIHelPyl33062_0956.
Phylogenomic databases
eggNOG	COG0670.
KO	K06890.
OMA	ENPELRW.
ProtClustDB	CLSK872467.
Family and domain databases
InterPro	IPR006214. Bax_inhibitor_1-related. [Graphical view]
PANTHER	PTHR23291. PTHR23291. 1 hit.
Pfam	PF01027. Bax1-I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y920_HELPY

Accession

Primary (citable) accession number: O25578

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 14, 2001
Last sequence update:	January 1, 1998
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program