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Protein
Submitted name:

Type I restriction enzyme M protein (HsdM)

Gene

HP_0850

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciHPY:HP0850-MONOMER.

Protein family/group databases

REBASEi3598. M.HpyAXIII.

Names & Taxonomyi

Protein namesi
Submitted name:
Type I restriction enzyme M protein (HsdM)Imported
Gene namesi
Ordered Locus Names:HP_0850Imported
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)Imported
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiO25521.
PRIDEiO25521.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HP_0848O255193EBI-7503998,EBI-9265942

Protein-protein interaction databases

DIPiDIP-3358N.
IntActiO25521. 8 interactions.
MINTiMINT-161863.
STRINGi85962.HP0850.

Structurei

3D structure databases

ProteinModelPortaliO25521.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 169153HsdM_NInterPro annotationAdd
BLAST
Domaini182 – 489308N6_MtaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105CVR. Bacteria.
COG0286. LUCA.
KOiK03427.
OMAiWASADIL.
OrthoDBiEOG64JFNB.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR022749. D12N6_MeTrfase_N.
IPR003356. DNA_methylase_A-5.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR004546. Restrct_endonuc_typeI_HsdM.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF12161. HsdM_N. 1 hit.
PF02384. N6_Mtase. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
TIGRFAMsiTIGR00497. hsdM. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O25521-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENNPNNNQA SLERNELHNT IWKVANELRG SVDGWDFKQY VLGILFYRYI
60 70 80 90 100
SENMTHYINK EERKRDPSFD YAKLSDEKAE RGRKHLIEQK GFFIPPSALF
110 120 130 140 150
CNALKNACHN EDLNVTLQNI FNEIEKSSLG TPSEENVKGL FADLDVNSNK
160 170 180 190 200
LGSSHQNRVE KLTKILEAIG GMQLGDYLKS GIDVFGDAYE YLMAMYASNA
210 220 230 240 250
GKSGGEFFTP QEVSELLAKI TLHGQESVNK VYDPCCGSGS LLLQFSKVLG
260 270 280 290 300
DKNVSKGYFG QEINLTTYNL CRINMFLHDI NYSKFHIAHG DTLLDPKHED
310 320 330 340 350
DEPFDAIVSN PPYSTKWVGD SNPILINDER FSPAGVLAPK NAADLAFTMH
360 370 380 390 400
MLSYLSNSGT AAIVEFPGVL YRGNAEAKIR EYLVKENVID CVIALPDNLF
410 420 430 440 450
FGTSIATCIL VLKKNKQDDT TLFIDASKEF VKEGKKNKLK ERNREKILQT
460 470 480 490 500
YIERKEIKHF CALANIEKIK ENDYNLSVNR YVEQEDTKEA IDIKALNSEI
510 520
AQIVEKQSAL RNRLESIIKE LEGGQNA
Length:527
Mass (Da):59,533
Last modified:January 1, 1998 - v1
Checksum:iB5881790D14F12E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07898.1.
PIRiB64626.
RefSeqiNP_207643.1. NC_000915.1.
WP_010875553.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07898; AAD07898; HP_0850.
GeneIDi899379.
KEGGihpy:HP0850.
PATRICi20592989. VBIHelPyl33062_0882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07898.1.
PIRiB64626.
RefSeqiNP_207643.1. NC_000915.1.
WP_010875553.1. NC_018939.1.

3D structure databases

ProteinModelPortaliO25521.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3358N.
IntActiO25521. 8 interactions.
MINTiMINT-161863.
STRINGi85962.HP0850.

Protein family/group databases

REBASEi3598. M.HpyAXIII.

Proteomic databases

PaxDbiO25521.
PRIDEiO25521.

Protocols and materials databases

DNASUi899379.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD07898; AAD07898; HP_0850.
GeneIDi899379.
KEGGihpy:HP0850.
PATRICi20592989. VBIHelPyl33062_0882.

Phylogenomic databases

eggNOGiENOG4105CVR. Bacteria.
COG0286. LUCA.
KOiK03427.
OMAiWASADIL.
OrthoDBiEOG64JFNB.

Enzyme and pathway databases

BioCyciHPY:HP0850-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR022749. D12N6_MeTrfase_N.
IPR003356. DNA_methylase_A-5.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR004546. Restrct_endonuc_typeI_HsdM.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF12161. HsdM_N. 1 hit.
PF02384. N6_Mtase. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
TIGRFAMsiTIGR00497. hsdM. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695Imported.

Entry informationi

Entry nameiO25521_HELPY
AccessioniPrimary (citable) accession number: O25521
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: March 16, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.