Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O25434

- RIMO_HELPY

UniProt

O25434 - RIMO_HELPY

Protein

Ribosomal protein S12 methylthiotransferase RimO

Gene

rimO

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.UniRule annotation

    Cofactori

    Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi16 – 161Iron-sulfur (4Fe-4S)UniRule annotation
    Metal bindingi50 – 501Iron-sulfur (4Fe-4S)UniRule annotation
    Metal bindingi82 – 821Iron-sulfur (4Fe-4S)UniRule annotation
    Metal bindingi151 – 1511Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation
    Metal bindingi155 – 1551Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation
    Metal bindingi158 – 1581Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-HAMAP
    2. iron ion binding Source: UniProtKB-HAMAP
    3. transferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid Source: UniProtKB-HAMAP
    2. RNA modification Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciHPY:HP0734-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribosomal protein S12 methylthiotransferase RimOUniRule annotation (EC:2.-.-.-UniRule annotation)
    Short name:
    S12 MTTaseUniRule annotation
    Short name:
    S12 methylthiotransferaseUniRule annotation
    Alternative name(s):
    Ribosome maturation factor RimOUniRule annotation
    Gene namesi
    Name:rimOUniRule annotation
    Ordered Locus Names:HP_0734
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 439439Ribosomal protein S12 methylthiotransferase RimOPRO_0000374856Add
    BLAST

    Proteomic databases

    PRIDEiO25434.

    Interactioni

    Protein-protein interaction databases

    STRINGi85962.HP0734.

    Structurei

    3D structure databases

    ProteinModelPortaliO25434.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 119113MTTase N-terminalUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the methylthiotransferase family. RimO subfamily.UniRule annotation
    Contains 1 MTTase N-terminal domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0621.
    OMAiPHDPFID.
    OrthoDBiEOG6P5ZD8.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.80.30.20. 1 hit.
    HAMAPiMF_01865. MTTase_RimO.
    InterProiIPR006638. Elp3/MiaB/NifB.
    IPR023970. MeThioTfrase/rSAM.
    IPR005839. Methylthiotransferase.
    IPR020612. Methylthiotransferase_CS.
    IPR013848. Methylthiotransferase_N.
    IPR012340. NA-bd_OB-fold.
    IPR005840. Ribosomal_S12_MeSTrfase_RimO.
    IPR007197. rSAM.
    IPR023404. rSAM_horseshoe.
    [Graphical view]
    PANTHERiPTHR11918. PTHR11918. 1 hit.
    PfamiPF04055. Radical_SAM. 1 hit.
    PF00919. UPF0004. 1 hit.
    [Graphical view]
    SMARTiSM00729. Elp3. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00089. TIGR00089. 1 hit.
    TIGR01125. TIGR01125. 1 hit.
    PROSITEiPS51449. MTTASE_N. 1 hit.
    PS01278. MTTASE_RADICAL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O25434-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVKENKQLC LISLGCSKNL VDSEVMLGKL YNYTLTNDAK SADVILINTC    50
    GFIESAKQES IQTILNAAKD KKEGAILIAS GCLSERYKDE IKELIPEVDI 100
    FTGVGDYDKI DIMIAKKQNQ FSEQVFLSEH YNARIITGSS VHAYVKISEG 150
    CNQKCSFCAI PSFKGKLQSR ELDSILKEVE NLALKGYTDM TFIAQDSSSF 200
    LYDKGQKDGL IQLIRAIDKQ QALKSARILY LYPSSTTLEL IGAIESSPIF 250
    QNYFDMPIQH ISDSMLKKMR RNSSQAHHLK LLDAMKQVKE SFIRSTIIVG 300
    HPEENESEFE ELSAFLDEFQ FDRLNIFAFS AEENTHAYSL EKVPKKTINA 350
    RIKALNKIAL KHQNHSFKAL LNKPIKALVE NKEGEYFYKA RDLRWAPEVD 400
    GEILINDSEL TTPLKPGHYT IAPSEFKDNI LLAKVLSPF 439
    Length:439
    Mass (Da):49,634
    Last modified:January 1, 1998 - v1
    Checksum:i59DDFC8721CC42EB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07780.1.
    PIRiF64611.
    RefSeqiNP_207528.1. NC_000915.1.
    YP_006934650.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07780; AAD07780; HP_0734.
    GeneIDi13869918.
    899326.
    KEGGiheo:C694_03770.
    hpy:HP0734.
    PATRICi20592755. VBIHelPyl33062_0766.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07780.1 .
    PIRi F64611.
    RefSeqi NP_207528.1. NC_000915.1.
    YP_006934650.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali O25434.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 85962.HP0734.

    Proteomic databases

    PRIDEi O25434.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07780 ; AAD07780 ; HP_0734 .
    GeneIDi 13869918.
    899326.
    KEGGi heo:C694_03770.
    hpy:HP0734.
    PATRICi 20592755. VBIHelPyl33062_0766.

    Phylogenomic databases

    eggNOGi COG0621.
    OMAi PHDPFID.
    OrthoDBi EOG6P5ZD8.

    Enzyme and pathway databases

    BioCyci HPY:HP0734-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.80.30.20. 1 hit.
    HAMAPi MF_01865. MTTase_RimO.
    InterProi IPR006638. Elp3/MiaB/NifB.
    IPR023970. MeThioTfrase/rSAM.
    IPR005839. Methylthiotransferase.
    IPR020612. Methylthiotransferase_CS.
    IPR013848. Methylthiotransferase_N.
    IPR012340. NA-bd_OB-fold.
    IPR005840. Ribosomal_S12_MeSTrfase_RimO.
    IPR007197. rSAM.
    IPR023404. rSAM_horseshoe.
    [Graphical view ]
    PANTHERi PTHR11918. PTHR11918. 1 hit.
    Pfami PF04055. Radical_SAM. 1 hit.
    PF00919. UPF0004. 1 hit.
    [Graphical view ]
    SMARTi SM00729. Elp3. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00089. TIGR00089. 1 hit.
    TIGR01125. TIGR01125. 1 hit.
    PROSITEi PS51449. MTTASE_N. 1 hit.
    PS01278. MTTASE_RADICAL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiRIMO_HELPY
    AccessioniPrimary (citable) accession number: O25434
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 26, 2009
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3