O25349 (O25349_HELPY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Quinone-reactive Ni/Fe hydrogenase, large subunit (HydB) EMBL AAD07692.1

Gene names

Ordered Locus Names:

HP_0632

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	578 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. RuleBase RU003896

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003896 Nickel RuleBase RU003896
Molecular function	Oxidoreductase RuleBase RU003896
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin hydrogenase activity Inferred from electronic annotation. Source: InterPro nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O25349 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 8804F5BBFF5C03F2	FASTA	578	64,397
	10 20 30 40 50 60 MSKKIVVDPI TRIEGHLRIE VIVDDDNVIT DAFSSSTLFR GLETIIKGRD PRDAGFIAQR 70 80 90 100 110 120 ICGVCTYSHY KAGITAVENA LGITPPLNAQ LVRSLMNMAL LFHDHVVHFY TLHGLDWCDI 130 140 150 160 170 180 MSALKADPIQ AAKLSFKYSP YPINTGAGEL KAVQKRLSDF AKSGSLGPFS NGYYGHKTYR 190 200 210 220 230 240 LSPEQNLIVL SHYLKLLEIQ REAAKMTAIF GAKQPHPQSL TVGGVTSVMD ILDPTRLAEW 250 260 270 280 290 300 KSKFEVVANF INHAYYPDLV MAGEMFANEQ SVIKGCGLRN FIAYEEVLLG RDKYLLSSGV 310 320 330 340 350 360 VLDGDISKLH PIDESLIKEE VTHSWYQYED TKEVQLHPYD GQTNPHYTGL KDGESVGIEN 370 380 390 400 410 420 KIIPAKVLDT KNKYSWIKSP RYDSKPMEVG PLSSVVVGLA AKNPYVTEVA TKFLKDTKLP 430 440 450 460 470 480 LEALFSTLGR TAARCIEAKT IADNGLLAFD ALVENLKSDQ STCAPYHIDK NQEYKGRYIG 490 500 510 520 530 540 QVPRGMLSHW VRIKNGVVEN YQAVVPSTWN AGPRDSQNQR GAYEMSLIGT KIADLTQPLE 550 560 570 IIRTIHSFDP CIACSVHVMD FKGQSLNEFK VEPNFAKF

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD07692.1.
PIR	H64598.
RefSeq	NP_207426.1. NC_000915.1.
3D structure databases
HSSP	HSSP built from PDB template 1UBL based on UniProtKB P21852.
ProteinModelPortal	O25349.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3326N.
MINT	MINT-178618.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	900022.
GenomeReviews	Gene locus HP_0632 in contig AE000511_GR.
KEGG	hpy:HP0632.
NMPDR	fig|85962.1.peg.624.
PATRIC	20592547. VBIHelPyl33062_0662.
TIGR	HP_0632.
Phylogenomic databases
HOGENOM	HBG733231.
OMA	PIPRIEG.
ProtClustDB	CLSK872401.
Family and domain databases
InterPro	IPR001501. Ni-dep_hyd_lsu. IPR018194. Ni-dep_hyd_lsu_Ni_BS. [Graphical view]
KO	K05922.
Pfam	PF00374. NiFeSe_Hases. 1 hit. [Graphical view]
PROSITE	PS00507. NI_HGENASE_L_1. 1 hit. PS00508. NI_HGENASE_L_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O25349_HELPY

Accession

Primary (citable) accession number: O25349

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)