Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Endonuclease III

Gene

HP_0602

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseImported, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciHPY:HP0602-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Endonuclease IIIImported
Gene namesi
Ordered Locus Names:HP_0602Imported
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)Imported
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei205 – 2051N6-carboxylysineCombined sources

Proteomic databases

PaxDbiO25323.

Interactioni

Protein-protein interaction databases

DIPiDIP-3459N.
IntActiO25323. 1 interaction.
MINTiMINT-173162.
STRINGi85962.HP0602.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PU6X-ray1.64A/B1-218[»]
1PU7X-ray1.93A/B1-218[»]
1PU8X-ray2.13A/B1-218[»]
ProteinModelPortaliO25323.
SMRiO25323. Positions 2-218.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 198160ENDO3cInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4108VTX. Bacteria.
COG2231. LUCA.
KOiK07457.
OMAiQNTKFEA.
OrthoDBiEOG65J50F.

Family and domain databases

Gene3Di1.10.1670.10. 1 hit.
1.10.340.30. 1 hit.
InterProiIPR011257. DNA_glycosylase.
IPR003265. HhH-GPD_domain.
IPR000445. HhH_motif.
IPR023170. HTH_base_excis_C.
[Graphical view]
PfamiPF00633. HHH. 1 hit.
PF00730. HhH-GPD. 1 hit.
[Graphical view]
SMARTiSM00478. ENDO3c. 1 hit.
[Graphical view]
SUPFAMiSSF48150. SSF48150. 1 hit.

Sequencei

Sequence statusi: Complete.

O25323-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDSFEILKA LKSLDLLKNA PSWWWPNALK FEALLGAVLT QNTKFEAVLK
60 70 80 90 100
SLENLKNAFI LENDDEINLK KIAYIEFSKL AECVRPSGFY NQKAKRLIDL
110 120 130 140 150
SKNILKDFQS FENFKQEVTR EWLLNQKGVG KESADAILCY VCAKEVMVVD
160 170 180 190 200
KYSYLFLKKI GIEIEDYDEL QHFFEKGVQE NLNSALALYE NTIPLAQLYA
210
RFHGKIVEFS KQKLELKL
Length:218
Mass (Da):25,286
Last modified:January 1, 1998 - v1
Checksum:i3844D222F21E4BB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07668.1.
PIRiB64595.
RefSeqiNP_207397.1. NC_000915.1.
WP_000887243.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07668; AAD07668; HP_0602.
GeneIDi899288.
KEGGiheo:C694_03115.
hpy:HP0602.
PATRICi20592483. VBIHelPyl33062_0630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07668.1.
PIRiB64595.
RefSeqiNP_207397.1. NC_000915.1.
WP_000887243.1. NC_018939.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PU6X-ray1.64A/B1-218[»]
1PU7X-ray1.93A/B1-218[»]
1PU8X-ray2.13A/B1-218[»]
ProteinModelPortaliO25323.
SMRiO25323. Positions 2-218.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3459N.
IntActiO25323. 1 interaction.
MINTiMINT-173162.
STRINGi85962.HP0602.

Proteomic databases

PaxDbiO25323.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD07668; AAD07668; HP_0602.
GeneIDi899288.
KEGGiheo:C694_03115.
hpy:HP0602.
PATRICi20592483. VBIHelPyl33062_0630.

Phylogenomic databases

eggNOGiENOG4108VTX. Bacteria.
COG2231. LUCA.
KOiK07457.
OMAiQNTKFEA.
OrthoDBiEOG65J50F.

Enzyme and pathway databases

BioCyciHPY:HP0602-MONOMER.

Family and domain databases

Gene3Di1.10.1670.10. 1 hit.
1.10.340.30. 1 hit.
InterProiIPR011257. DNA_glycosylase.
IPR003265. HhH-GPD_domain.
IPR000445. HhH_motif.
IPR023170. HTH_base_excis_C.
[Graphical view]
PfamiPF00633. HHH. 1 hit.
PF00730. HhH-GPD. 1 hit.
[Graphical view]
SMARTiSM00478. ENDO3c. 1 hit.
[Graphical view]
SUPFAMiSSF48150. SSF48150. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695Imported.
  2. "Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases."
    Eichman B.F., O'Rourke E.J., Radicella J.P., Ellenberger T.
    EMBO J. 22:4898-4909(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.64 ANGSTROMS), CARBOXYLATION AT LYS-205.

Entry informationi

Entry nameiO25323_HELPY
AccessioniPrimary (citable) accession number: O25323
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.