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O25318 (O25318_HELPY) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

Uncharacterized protein EMBL AAD07665.1
Gene names
Ordered Locus Names:C694_03080 EMBL AFV41817.1, HP_0596 EMBL AAD07665.1
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP] EMBL AAD07665.1
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site601Citrate PDB 2WCQ
Binding site771Citrate PDB 2WCQ

Sequences

Sequence LengthMass (Da)Tools
O25318 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F643AFD91293D9CF

FASTA19221,878
        10         20         30         40         50         60 
MLEKSFLKSK QLFLCGLGVL MLQACTCPNT SQRNSFLQDV PYWMLQNRSE YITQGVDSSH 

        70         80         90        100        110        120 
IVDGKKTEEI EKIATKRATI RVAQNIVHKL KEAYLSKTNR IKQKITNEMF IQMTQPIYDS 

       130        140        150        160        170        180 
LMNVDRLGIY INPNNEEVFA LVRARGFDKD ALSEGLHKMS LDNQAVSILV AKVEEIFKDS 

       190 
VNYGDVKVPI AM 

« Hide

References

« Hide 'large scale' references
[1]"The complete genome sequence of the gastric pathogen Helicobacter pylori."
Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.P., Gill S., Dougherty B.A., Nelson K., Quackenbush J., Zhou L., Kirkness E.F., Peterson S., Loftus B., Richardson D., Dodson R. expand/collapse author list , Khalak H.G., Glodek A., McKenney K., Fitzegerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.
Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 26695 EMBL AAD07665.1 and ATCC 700392 / 26695.
[2]White O.
Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 26695.
[3]"Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein."
Tsuge H., Tsurumura T., Utsunomiya H., Kise D., Kuzuhara T., Watanabe T., Fujiki H., Suganuma M.
Biochem. Biophys. Res. Commun. 388:193-198(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.47 ANGSTROMS) OF 28-192.
[4]"Structures of the tumor necrosis factor alpha inducing protein Tipalpha: a novel virulence factor from Helicobacter pylori."
Tosi T., Cioci G., Jouravleva K., Dian C., Terradot L.
FEBS Lett. 583:1581-1585(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 34-192 IN COMPLEX WITH CITRATE.
[5]"Crystal structure of the TNF-alpha-Inducing protein (Tipalpha) from Helicobacter pylori: Insights into Its DNA-binding activity."
Jang J.Y., Yoon H.J., Yoon J.Y., Kim H.S., Lee S.J., Kim K.H., Kim d.o. .J., Jang S., Han B.G., Lee B.I., Suh S.W.
J. Mol. Biol. 392:191-197(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 28-192.
[6]"Crystal structure of TNF-?-inducing protein from Helicobacter pylori in active form reveals the intrinsic molecular flexibility for unique DNA-binding."
Gao M., Li D., Hu Y., Zhang Y., Zou Q., Wang D.C.
PLoS ONE 7:e41871-e41871(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 25-192.
[7]"Draft genome of Helicobacter pylori."
Manolov A., Prihodko E., Larin A., Karpova I., Semashko T., Alexeev D., Kostrjukova E., Govorun V.
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700392 / 26695.
[8]"Draft genome of Helicobacter pylori."
Chelysheva V., Selezneva O., Alexeev D., Manolov A., Prihodko E., Larin A., Karpova I., Semashko T., Kostryukova E., Govorun V., Momynaliev K.
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 26695 EMBL AFV41817.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07665.1.
CP003904 Genomic DNA. Translation: AFV41817.1.
PIRD64594.
RefSeqNP_207391.1. NC_000915.1.
YP_006934520.1. NC_018939.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2WCQX-ray1.90A/B34-192[»]
2WCRX-ray1.70A/B34-192[»]
3GIOX-ray2.40A/B28-192[»]
3GUQX-ray2.47A28-192[»]
3VNCX-ray2.60A/B25-192[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING85962.HP0596.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07665; AAD07665; HP_0596.
AFV41817; AFV41817; C694_03080.
GeneID898978.
KEGGheo:C694_03080.
hpy:HP0596.
PATRIC20592471. VBIHelPyl33062_0624.

Phylogenomic databases

OMAKMSLDNQ.
OrthoDBEOG6K9QGV.

Enzyme and pathway databases

BioCycHPY:HP0596-MONOMER.

Family and domain databases

ProtoNetSearch...

Other

EvolutionaryTraceO25318.

Entry information

Entry nameO25318_HELPY
AccessionPrimary (citable) accession number: O25318
Entry history
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)