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O25286 (O25286_HELPY) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=1.1.1.100 EMBL AFV41780.1

3-ketoacyl-acyl carrier protein reductase (FabG) EMBL AAD07627.1
Gene names
Name:fabG EMBL AFV41780.1
Ordered Locus Names:C694_02895 EMBL AFV41780.1, HP_0561 EMBL AAD07627.1
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP] EMBL AAD07627.1
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length247 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding63 – 642NAD PDB 4IIN
Nucleotide binding185 – 1906NAD PDB 4IIN

Sites

Metal binding2371Potassium PDB 4IIN
Metal binding2381Potassium; via carbonyl oxygen PDB 4IIN
Binding site171NAD; via amide nitrogen PDB 4IIN
Binding site371NAD PDB 4IIN
Binding site901NAD; via carbonyl oxygen PDB 4IIN
Binding site1131NAD PDB 4IIN
Binding site1421Acetate PDB 4IIN
Binding site1551Acetate PDB 4IIN
Binding site1551NAD PDB 4IIN
Binding site1591NAD PDB 4IIN

Sequences

Sequence LengthMass (Da)Tools
O25286 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 3F76B625834EA1CB

FASTA24726,668
        10         20         30         40         50         60 
MQFTGKNVLI TGASKGIGAE IAKTLASMGL KVWINYRSNA EVADALKNEL EEKGYKAAVI 

        70         80         90        100        110        120 
KFDAASESDF IEAIQTIVQS DGGLSYLVNN AGVVRDKLAI KMKTEDFHHV IDNNLTSAFI 

       130        140        150        160        170        180 
GCREALKVMS KSRFGSVVNV ASIIGERGNM GQTNYSASKG GMIAMSKSFA YEGALRNIRF 

       190        200        210        220        230        240 
NSVTPGFIET DMNANLKDEL KADYVKNIPL NRLGSAKEVA EAVAFLLSDH SSYITGETLK 


VNGGLYM 

« Hide

References

« Hide 'large scale' references
[1]"The complete genome sequence of the gastric pathogen Helicobacter pylori."
Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. expand/collapse author list , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.
Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 26695 EMBL AAD07627.1 and ATCC 700392 / 26695.
[2]White O.
Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 26695.
[3]"Draft genome of Helicobacter pylori."
Chelysheva V., Selezneva O., Alexeev D., Manolov A., Prihodko E., Larin A., Karpova I., Semashko T., Kostryukova E., Govorun V., Momynaliev K.
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 26695 EMBL AFV41780.1.
[4]"Draft genome of Helicobacter pylori."
Manolov A., Prihodko E., Larin A., Karpova I., Semashko T., Alexeev D., Kostrjukova E., Govorun V.
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700392 / 26695.
[5]"Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+."
Center for Structural Genomics of Infectious Diseases (CSGID)
Hou J., Osinski T., Zheng H., Shumilin I., Shabalin I., Shatsman S., Anderson W.F., Minor W.
Submitted (DEC-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) IN COMPLEX WITH ACETATE; NAD AND POTASSIUM.
[6]"Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695."
Center for Structural Genomics of Infectious Diseases (CSGID)
Hou J., Osinski T., Zheng H., Shumilin I., Shabalin I.G., Shatsman S., Anderson W.F., Minor W.
Submitted (DEC-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.54 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07627.1.
CP003904 Genomic DNA. Translation: AFV41780.1.
PIRA64590.
RefSeqNP_207356.1. NC_000915.1.
YP_006934483.1. NC_018939.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4IINX-ray2.40A/B/C/D1-247[»]
4IJKX-ray2.54A/B/C/D1-247[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING85962.HP0561.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07627; AAD07627; HP_0561.
AFV41780; AFV41780; C694_02895.
GeneID13869751.
900034.
KEGGheo:C694_02895.
hpy:HP0561.
PATRIC20592395. VBIHelPyl33062_0586.

Phylogenomic databases

KOK00059.
OMATDMTHGL.
OrthoDBEOG6N3CR8.
ProtClustDBPRK05653.

Enzyme and pathway databases

BioCycHPY:HP0561-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameO25286_HELPY
AccessionPrimary (citable) accession number: O25286
Entry history
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)