Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O25225

- TYPA_HELPY

UniProt

O25225 - TYPA_HELPY

Protein

GTP-binding protein TypA/BipA homolog

Gene

typA

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Not known; probably interacts with the ribosomes in a GTP dependent manner.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 188GTPBy similarity
    Nucleotide bindingi73 – 775GTPBy similarity
    Nucleotide bindingi127 – 1304GTPBy similarity

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-KW

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHPY:HP0480-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP-binding protein TypA/BipA homolog
    Gene namesi
    Name:typA
    Ordered Locus Names:HP_0480
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 599599GTP-binding protein TypA/BipA homologPRO_0000091555Add
    BLAST

    Proteomic databases

    PRIDEiO25225.

    Interactioni

    Protein-protein interaction databases

    IntActiO25225. 5 interactions.
    MINTiMINT-4074340.
    STRINGi85962.HP0480.

    Structurei

    3D structure databases

    ProteinModelPortaliO25225.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 197196tr-type GPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily.PROSITE-ProRule annotation
    Contains 1 tr-type G (guanine nucleotide-binding) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1217.
    KOiK06207.
    OMAiPPKIMTL.
    OrthoDBiEOG67HJSM.

    Family and domain databases

    Gene3Di3.30.70.240. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR000640. EFG_V.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR006298. TypA_GTP-bd.
    [Graphical view]
    PANTHERiPTHR23115:SF14. PTHR23115:SF14. 1 hit.
    PfamiPF00679. EFG_C. 1 hit.
    PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SMARTiSM00838. EFG_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54980. SSF54980. 2 hits.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.
    TIGR01394. TypA_BipA. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O25225-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNIRNIAVI AHVDHGKTTL VDGLLSQSGT FSEREKVDER VMDSNDLERE    50
    RGITILSKNT AIYYKDTKIN IIDTPGHADF GGEVERVLKM VDGVLLLVDA 100
    QEGVMPQTKF VVKKALSFGI CPIVVVNKID KPAAEPDRVV DEVFDLFVAM 150
    GASDKQLDFP VVYAAARDGY AMKSLDDEKK NLEPLFETIL EHVPSPSGSV 200
    DEPLQMQIFT LDYDNYVGKI GIARVFNGSV KKNESVLLMK SDGSKENGRI 250
    TKLIGFLGLA RTEIENAYAG DIVAIAGFNA MDVGDSVVDP ANPMPLDPMH 300
    LEEPTMSVYF AVNDSPLAGL EGKHVTANKL KDRLLKEMQT NIAMKCEEMG 350
    EGKFKVSGRG ELQITILAEN LRREGFEFSI SRPEVIIKEE NGVKCEPFEH 400
    LVIDTPQDFS GAIIERLGKR KAEMKAMNPM SDGYTRLEFE IPARGLIGYR 450
    SEFLTDTKGE GVMNHSFLEF RPFSGSVESR KNGALISMEN GEATAFSLFN 500
    IQERGTLFIN PQTKVYVGMV IGEHSRDNDL DVNPIKSKHL TNMRASGSDD 550
    AIKLTPPRTM VLERALEWIE EDEILEVTPL NLRIRKKILD PNMRKRAKK 599
    Length:599
    Mass (Da):66,676
    Last modified:January 1, 1998 - v1
    Checksum:i93E785506BCAEEA9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07546.1.
    PIRiH64579.
    RefSeqiNP_207278.1. NC_000915.1.
    YP_006934400.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07546; AAD07546; HP_0480.
    GeneIDi13869668.
    898837.
    KEGGiheo:C694_02460.
    hpy:HP0480.
    PATRICi20592231. VBIHelPyl33062_0504.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07546.1 .
    PIRi H64579.
    RefSeqi NP_207278.1. NC_000915.1.
    YP_006934400.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali O25225.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi O25225. 5 interactions.
    MINTi MINT-4074340.
    STRINGi 85962.HP0480.

    Proteomic databases

    PRIDEi O25225.

    Protocols and materials databases

    DNASUi 898837.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07546 ; AAD07546 ; HP_0480 .
    GeneIDi 13869668.
    898837.
    KEGGi heo:C694_02460.
    hpy:HP0480.
    PATRICi 20592231. VBIHelPyl33062_0504.

    Phylogenomic databases

    eggNOGi COG1217.
    KOi K06207.
    OMAi PPKIMTL.
    OrthoDBi EOG67HJSM.

    Enzyme and pathway databases

    BioCyci HPY:HP0480-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.240. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR000640. EFG_V.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR006298. TypA_GTP-bd.
    [Graphical view ]
    PANTHERi PTHR23115:SF14. PTHR23115:SF14. 1 hit.
    Pfami PF00679. EFG_C. 1 hit.
    PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SMARTi SM00838. EFG_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54980. SSF54980. 2 hits.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    TIGR01394. TypA_BipA. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiTYPA_HELPY
    AccessioniPrimary (citable) accession number: O25225
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3