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O25225 (TYPA_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTP-binding protein TypA/BipA homolog
Gene names
Name:typA
Ordered Locus Names:HP_0480
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length599 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Not known; probably interacts with the ribosomes in a GTP dependent manner By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. TypA subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 599599GTP-binding protein TypA/BipA homolog
PRO_0000091555

Regions

Nucleotide binding11 – 188GTP By similarity
Nucleotide binding73 – 775GTP By similarity
Nucleotide binding127 – 1304GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
O25225 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 93E785506BCAEEA9

FASTA59966,676
        10         20         30         40         50         60 
MKNIRNIAVI AHVDHGKTTL VDGLLSQSGT FSEREKVDER VMDSNDLERE RGITILSKNT 

        70         80         90        100        110        120 
AIYYKDTKIN IIDTPGHADF GGEVERVLKM VDGVLLLVDA QEGVMPQTKF VVKKALSFGI 

       130        140        150        160        170        180 
CPIVVVNKID KPAAEPDRVV DEVFDLFVAM GASDKQLDFP VVYAAARDGY AMKSLDDEKK 

       190        200        210        220        230        240 
NLEPLFETIL EHVPSPSGSV DEPLQMQIFT LDYDNYVGKI GIARVFNGSV KKNESVLLMK 

       250        260        270        280        290        300 
SDGSKENGRI TKLIGFLGLA RTEIENAYAG DIVAIAGFNA MDVGDSVVDP ANPMPLDPMH 

       310        320        330        340        350        360 
LEEPTMSVYF AVNDSPLAGL EGKHVTANKL KDRLLKEMQT NIAMKCEEMG EGKFKVSGRG 

       370        380        390        400        410        420 
ELQITILAEN LRREGFEFSI SRPEVIIKEE NGVKCEPFEH LVIDTPQDFS GAIIERLGKR 

       430        440        450        460        470        480 
KAEMKAMNPM SDGYTRLEFE IPARGLIGYR SEFLTDTKGE GVMNHSFLEF RPFSGSVESR 

       490        500        510        520        530        540 
KNGALISMEN GEATAFSLFN IQERGTLFIN PQTKVYVGMV IGEHSRDNDL DVNPIKSKHL 

       550        560        570        580        590 
TNMRASGSDD AIKLTPPRTM VLERALEWIE EDEILEVTPL NLRIRKKILD PNMRKRAKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07546.1.
PIRH64579.
RefSeqNP_207278.1. NC_000915.1.
YP_006934400.1. NC_018939.1.

3D structure databases

ProteinModelPortalO25225.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO25225. 1 interaction.
MINTMINT-4074340.
STRING85962.HP0480.

Proteomic databases

PRIDEO25225.

Protocols and materials databases

DNASU898837.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07546; AAD07546; HP_0480.
GeneID13869668.
898837.
KEGGheo:C694_02460.
hpy:HP0480.
PATRIC20592231. VBIHelPyl33062_0504.

Phylogenomic databases

eggNOGCOG1217.
KOK06207.
OMARVLNMAD.
OrthoDBEOG67HJSM.
ProtClustDBCLSK872368.

Enzyme and pathway databases

BioCycHPY:HP0480-MONOMER.

Family and domain databases

Gene3D3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProIPR000795. EF_GTP-bd_dom.
IPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR006298. TypA_GTP-bd.
[Graphical view]
PANTHERPTHR23115:SF14. PTHR23115:SF14. 1 hit.
PfamPF00679. EFG_C. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SMARTSM00838. EFG_C. 1 hit.
[Graphical view]
SUPFAMSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsTIGR00231. small_GTP. 1 hit.
TIGR01394. TypA_BipA. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPA_HELPY
AccessionPrimary (citable) accession number: O25225
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names