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Protein

GTP-binding protein TypA/BipA homolog

Gene

typA

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Not known; probably interacts with the ribosomes in a GTP dependent manner.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18GTPBy similarity8
Nucleotide bindingi73 – 77GTPBy similarity5
Nucleotide bindingi127 – 130GTPBy similarity4

GO - Molecular functioni

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP0480-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein TypA/BipA homolog
Gene namesi
Name:typA
Ordered Locus Names:HP_0480
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000915551 – 599GTP-binding protein TypA/BipA homologAdd BLAST599

Proteomic databases

PaxDbiO25225.

Interactioni

Protein-protein interaction databases

IntActiO25225. 5 interactors.
MINTiMINT-4074340.
STRINGi85962.HP0480.

Structurei

3D structure databases

ProteinModelPortaliO25225.
SMRiO25225.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 197tr-type GPROSITE-ProRule annotationAdd BLAST196

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105CI3. Bacteria.
COG1217. LUCA.
KOiK06207.
OMAiSMLFTIN.

Family and domain databases

CDDicd03710. BipA_TypA_C. 1 hit.
InterProiView protein in InterPro
IPR035651. BipA_V.
IPR035647. EFG_III/V.
IPR000640. EFG_V-like.
IPR004161. EFTu-like_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR006298. TypA_GTP-bd.
PANTHERiPTHR42908:SF5. PTHR42908:SF5. 1 hit.
PfamiView protein in Pfam
PF00679. EFG_C. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
TIGR01394. TypA_BipA. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O25225-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNIRNIAVI AHVDHGKTTL VDGLLSQSGT FSEREKVDER VMDSNDLERE
60 70 80 90 100
RGITILSKNT AIYYKDTKIN IIDTPGHADF GGEVERVLKM VDGVLLLVDA
110 120 130 140 150
QEGVMPQTKF VVKKALSFGI CPIVVVNKID KPAAEPDRVV DEVFDLFVAM
160 170 180 190 200
GASDKQLDFP VVYAAARDGY AMKSLDDEKK NLEPLFETIL EHVPSPSGSV
210 220 230 240 250
DEPLQMQIFT LDYDNYVGKI GIARVFNGSV KKNESVLLMK SDGSKENGRI
260 270 280 290 300
TKLIGFLGLA RTEIENAYAG DIVAIAGFNA MDVGDSVVDP ANPMPLDPMH
310 320 330 340 350
LEEPTMSVYF AVNDSPLAGL EGKHVTANKL KDRLLKEMQT NIAMKCEEMG
360 370 380 390 400
EGKFKVSGRG ELQITILAEN LRREGFEFSI SRPEVIIKEE NGVKCEPFEH
410 420 430 440 450
LVIDTPQDFS GAIIERLGKR KAEMKAMNPM SDGYTRLEFE IPARGLIGYR
460 470 480 490 500
SEFLTDTKGE GVMNHSFLEF RPFSGSVESR KNGALISMEN GEATAFSLFN
510 520 530 540 550
IQERGTLFIN PQTKVYVGMV IGEHSRDNDL DVNPIKSKHL TNMRASGSDD
560 570 580 590
AIKLTPPRTM VLERALEWIE EDEILEVTPL NLRIRKKILD PNMRKRAKK
Length:599
Mass (Da):66,676
Last modified:January 1, 1998 - v1
Checksum:i93E785506BCAEEA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07546.1.
PIRiH64579.
RefSeqiNP_207278.1. NC_000915.1.
WP_000790221.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07546; AAD07546; HP_0480.
GeneIDi898837.
KEGGiheo:C694_02460.
hpy:HP0480.
PATRICifig|85962.47.peg.515.

Similar proteinsi

Entry informationi

Entry nameiTYPA_HELPY
AccessioniPrimary (citable) accession number: O25225
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: August 30, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families