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O25136 (DCD_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxycytidine triphosphate deaminase

Short name=dCTP deaminase
EC=3.5.4.13
Gene names
Name:dcd
Ordered Locus Names:HP_0372
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146

Sequence similarities

Belongs to the dCTP deaminase family.

Sequence caution

The sequence AAD07441.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdUMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

dUTP biosynthetic process

Inferred from electronic annotation. Source: InterPro

pyrimidine ribonucleotide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functiondCTP deaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146
PRO_0000155990

Sequences

Sequence LengthMass (Da)Tools
O25136 [UniParc].

Last modified December 1, 2000. Version 2.
Checksum: F45AEE3C3F040876

FASTA18820,904
        10         20         30         40         50         60 
MGLKADSWIK KMSLEHGMIS PFCEKQVGKN VISYGLSSYG YDIRVGSEFM LFDNKNALID 

        70         80         90        100        110        120 
PKNFDPNNAT KIDASKEGYF ILPANAFALA HTIEYFKMPK DTLAICLGKS TYARCGIIVN 

       130        140        150        160        170        180 
VTPFEPEFEG YITIEISNTT NLPAKVYANE GIAQVVFLQG DEMCEQSYKD RGGKYQGQVG 


ITLPKILK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07441.1. Different initiation.
PIRD64566.
RefSeqNP_207170.1. NC_000915.1.
YP_006934296.1. NC_018939.1.

3D structure databases

ProteinModelPortalO25136.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO25136. 1 interaction.
MINTMINT-169872.
STRING85962.HP0372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07441; AAD07441; HP_0372.
GeneID898857.
KEGGheo:C694_01890.
hpy:HP0372.
PATRIC20591981. VBIHelPyl33062_0384.

Phylogenomic databases

eggNOGCOG0717.
KOK01494.
OMAEFEGHIT.
OrthoDBEOG67DPKR.

Enzyme and pathway databases

UniPathwayUPA00610; UER00665.

Family and domain databases

Gene3D2.70.40.10. 1 hit.
HAMAPMF_00146. dCTP_deaminase.
InterProIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMSSF51283. SSF51283. 1 hit.
TIGRFAMsTIGR02274. dCTP_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCD_HELPY
AccessionPrimary (citable) accession number: O25136
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: July 9, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names