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O25098 (MIND_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Septum site-determining protein MinD
Alternative name(s):
Cell division inhibitor MinD
Gene names
Name:minD
Ordered Locus Names:HP_0331
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings By similarity.

Subunit structure

Interacts with MinC and FtsZ By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ParA family. MinD subfamily.

Ontologies

Keywords
   Biological processCell cycle
Cell division
Septation
   Cellular componentCell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processbarrier septum site selection

Inferred from electronic annotation. Source: InterPro

   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Septum site-determining protein MinD
PRO_0000201971

Regions

Nucleotide binding10 – 178ATP Potential

Sequences

Sequence LengthMass (Da)Tools
O25098 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 9E14766E8D309476

FASTA26829,294
        10         20         30         40         50         60 
MAIVVTITSG KGGVGKSTTT ANLAIGLAES GKKVVAVDFD IGLRNLDMIL GLENRIVYDV 

        70         80         90        100        110        120 
VDVMEKNCNL SQALITDKKT KNLSFLAASQ SKDKNILDKE KVAILINALR ADFDYILIDS 

       130        140        150        160        170        180 
PAGIESGFEH AILHADMALV VVTPEVSSLR DSDRVVGIID AKSNRAKKGM EVHKHLIINR 

       190        200        210        220        230        240 
LKPELVANGE MISIEEVLKI LCLPLIGIIP EDHHIISATN KGEPVIRTDC ESAKAYQRIT 

       250        260 
RRILGEEVEY VEFKAKRGFF SALKGIFS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07400.1.
PIRC64561.
RefSeqNP_207129.1. NC_000915.1.
YP_006934259.1. NC_018939.1.

3D structure databases

ProteinModelPortalO25098.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-3247N.
IntActO25098. 1 interaction.
MINTMINT-161558.
STRING85962.HP0331.

Proteomic databases

PRIDEO25098.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD07400; AAD07400; HP_0331.
GeneID13869518.
900172.
KEGGheo:C694_01675.
hpy:HP0331.
PATRIC20591897. VBIHelPyl33062_0345.

Phylogenomic databases

eggNOGCOG2894.
KOK03609.
OMARNLDMIL.
OrthoDBEOG6NPMB6.
ProtClustDBCLSK872336.

Enzyme and pathway databases

BioCycHPY:HP0331-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR025501. MinD.
IPR010223. MinD_bac-type.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR13696:SF1. PTHR13696:SF1. 1 hit.
PfamPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFPIRSF003092. MinD. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01968. minD_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMIND_HELPY
AccessionPrimary (citable) accession number: O25098
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names