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Protein

Septum site-determining protein MinD

Gene

minD

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 178ATPSequence Analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP0331-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Septum site-determining protein MinD
Alternative name(s):
Cell division inhibitor MinD
Gene namesi
Name:minD
Ordered Locus Names:HP_0331
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 268268Septum site-determining protein MinDPRO_0000201971Add
BLAST

Proteomic databases

PRIDEiO25098.

Interactioni

Subunit structurei

Interacts with MinC and FtsZ.By similarity

Protein-protein interaction databases

DIPiDIP-3247N.
IntActiO25098. 4 interactions.
MINTiMINT-161558.
STRINGi85962.HP0331.

Structurei

3D structure databases

ProteinModelPortaliO25098.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ParA family. MinD subfamily.Curated

Phylogenomic databases

eggNOGiCOG2894.
KOiK03609.
OMAiRNLDMIL.
OrthoDBiEOG6NPMB6.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR025501. MinD.
IPR010223. MinD_bac-type.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFiPIRSF003092. MinD. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01968. minD_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

O25098-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIVVTITSG KGGVGKSTTT ANLAIGLAES GKKVVAVDFD IGLRNLDMIL
60 70 80 90 100
GLENRIVYDV VDVMEKNCNL SQALITDKKT KNLSFLAASQ SKDKNILDKE
110 120 130 140 150
KVAILINALR ADFDYILIDS PAGIESGFEH AILHADMALV VVTPEVSSLR
160 170 180 190 200
DSDRVVGIID AKSNRAKKGM EVHKHLIINR LKPELVANGE MISIEEVLKI
210 220 230 240 250
LCLPLIGIIP EDHHIISATN KGEPVIRTDC ESAKAYQRIT RRILGEEVEY
260
VEFKAKRGFF SALKGIFS
Length:268
Mass (Da):29,294
Last modified:January 1, 1998 - v1
Checksum:i9E14766E8D309476
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07400.1.
PIRiC64561.
RefSeqiNP_207129.1. NC_000915.1.
WP_001019069.1. NC_018939.1.
YP_006934259.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07400; AAD07400; HP_0331.
GeneIDi900172.
KEGGiheo:C694_01675.
hpy:HP0331.
PATRICi20591897. VBIHelPyl33062_0345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07400.1.
PIRiC64561.
RefSeqiNP_207129.1. NC_000915.1.
WP_001019069.1. NC_018939.1.
YP_006934259.1. NC_018939.1.

3D structure databases

ProteinModelPortaliO25098.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3247N.
IntActiO25098. 4 interactions.
MINTiMINT-161558.
STRINGi85962.HP0331.

Proteomic databases

PRIDEiO25098.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD07400; AAD07400; HP_0331.
GeneIDi900172.
KEGGiheo:C694_01675.
hpy:HP0331.
PATRICi20591897. VBIHelPyl33062_0345.

Phylogenomic databases

eggNOGiCOG2894.
KOiK03609.
OMAiRNLDMIL.
OrthoDBiEOG6NPMB6.

Enzyme and pathway databases

BioCyciHPY:HP0331-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR025501. MinD.
IPR010223. MinD_bac-type.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFiPIRSF003092. MinD. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01968. minD_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiMIND_HELPY
AccessioniPrimary (citable) accession number: O25098
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: May 27, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.