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O24993

- PLSX_HELPY

UniProt

O24993 - PLSX_HELPY

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Protein
Phosphate acyltransferase
Gene
plsX, HP_0201
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the reversible formation of acyl-phosphate (acyl-PO4) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA By similarity.UniRule annotation

Catalytic activityi

Acyl-[acyl-carrier-protein] + phosphate = acyl-phosphate + [acyl-carrier-protein].UniRule annotation

Pathwayi

GO - Molecular functioni

  1. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
  2. transferase activity, transferring acyl groups other than amino-acyl groups Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: InterPro
  2. phospholipid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00085.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acyltransferase (EC:2.3.1.n2)
Alternative name(s):
Acyl-ACP phosphotransacylase
Acyl-[acyl-carrier-protein]--phosphate acyltransferase
Phosphate-acyl-ACP acyltransferase
Gene namesi
Name:plsX
Ordered Locus Names:HP_0201
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm By similarity
Note: Associated with the membrane possibly through PlsY By similarity.UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 337337Phosphate acyltransferaseUniRule annotation
PRO_0000189887Add
BLAST

Interactioni

Subunit structurei

Homodimer. Probably interacts with PlsY By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi85962.HP0201.

Structurei

3D structure databases

ProteinModelPortaliO24993.

Family & Domainsi

Sequence similaritiesi

Belongs to the PlsX family.

Phylogenomic databases

eggNOGiCOG0416.
KOiK03621.
OMAiHNVMENL.
OrthoDBiEOG68H88P.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
HAMAPiMF_00019. PlsX.
InterProiIPR003664. FA_synthesis.
IPR024084. IsoPropMal-DH-like_dom.
IPR012281. Phospholipid_synth_PlsX-like.
[Graphical view]
PfamiPF02504. FA_synthesis. 1 hit.
[Graphical view]
PIRSFiPIRSF002465. Phsphlp_syn_PlsX. 1 hit.
TIGRFAMsiTIGR00182. plsX. 1 hit.

Sequencei

Sequence statusi: Complete.

O24993-1 [UniParc]FASTAAdd to Basket

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MKIVIDLMGA DHGVLPVIEG VSRALENKSF STVLVGDKDK ATPFISKELA    50
SKVEMIHTQD YIKMEEAATE AIKRKESSIY LGMDILKNGA DALISAGHSG 100
ATMGLATLRL GRIKGVERPA ICTLMPSVGK RPSVLLDAGA NTDCKPEYLI 150
DFALMGYEYA KSVLHYDSPK VGLLSNGEED IKGNMLVKET HKMLKAYDFF 200
YGNVEGSDIF KGVVDVVVCD GFMGNVVLKT TEGVASAIGS IFKDEIKSSF 250
KSKMGALMLK NAFDILKQKT DYAEYGGAPL LGVNKSVIIS HGKSNARAIE 300
CAIYQAISAV ESQVCLRITQ AFESLKPSVS QSDQQDA 337
Length:337
Mass (Da):36,352
Last modified:May 30, 2000 - v2
Checksum:i7916CD4F5911B23C
GO

Sequence cautioni

The sequence AAD07269.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07269.1. Different initiation.
PIRiA64545.
RefSeqiNP_207000.1. NC_000915.1.
YP_006934124.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07269; AAD07269; HP_0201.
GeneIDi13869380.
898919.
KEGGiheo:C694_01000.
hpy:HP0201.
PATRICi20591623. VBIHelPyl33062_0211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07269.1 . Different initiation.
PIRi A64545.
RefSeqi NP_207000.1. NC_000915.1.
YP_006934124.1. NC_018939.1.

3D structure databases

ProteinModelPortali O24993.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85962.HP0201.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07269 ; AAD07269 ; HP_0201 .
GeneIDi 13869380.
898919.
KEGGi heo:C694_01000.
hpy:HP0201.
PATRICi 20591623. VBIHelPyl33062_0211.

Phylogenomic databases

eggNOGi COG0416.
KOi K03621.
OMAi HNVMENL.
OrthoDBi EOG68H88P.

Enzyme and pathway databases

UniPathwayi UPA00085 .

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
HAMAPi MF_00019. PlsX.
InterProi IPR003664. FA_synthesis.
IPR024084. IsoPropMal-DH-like_dom.
IPR012281. Phospholipid_synth_PlsX-like.
[Graphical view ]
Pfami PF02504. FA_synthesis. 1 hit.
[Graphical view ]
PIRSFi PIRSF002465. Phsphlp_syn_PlsX. 1 hit.
TIGRFAMsi TIGR00182. plsX. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiPLSX_HELPY
AccessioniPrimary (citable) accession number: O24993
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: September 3, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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