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O24993

- PLSX_HELPY

UniProt

O24993 - PLSX_HELPY

Protein

Phosphate acyltransferase

Gene

plsX

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 2 (30 May 2000)
      Previous versions | rss
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    Functioni

    Catalyzes the reversible formation of acyl-phosphate (acyl-PO4) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.UniRule annotation

    Catalytic activityi

    Acyl-[acyl-carrier-protein] + phosphate = acyl-phosphate + [acyl-carrier-protein].UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
    2. transferase activity, transferring acyl groups other than amino-acyl groups Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: InterPro
    2. phospholipid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Enzyme and pathway databases

    UniPathwayiUPA00085.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate acyltransferaseUniRule annotation (EC:2.3.1.n2UniRule annotation)
    Alternative name(s):
    Acyl-ACP phosphotransacylaseUniRule annotation
    Acyl-[acyl-carrier-protein]--phosphate acyltransferaseUniRule annotation
    Phosphate-acyl-ACP acyltransferaseUniRule annotation
    Gene namesi
    Name:plsXUniRule annotation
    Ordered Locus Names:HP_0201
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation
    Note: Associated with the membrane possibly through PlsY.UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 337337Phosphate acyltransferasePRO_0000189887Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer. Probably interacts with PlsY.UniRule annotation

    Protein-protein interaction databases

    STRINGi85962.HP0201.

    Structurei

    3D structure databases

    ProteinModelPortaliO24993.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PlsX family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0416.
    KOiK03621.
    OMAiHNVMENL.
    OrthoDBiEOG68H88P.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    HAMAPiMF_00019. PlsX.
    InterProiIPR003664. FA_synthesis.
    IPR024084. IsoPropMal-DH-like_dom.
    IPR012281. Phospholipid_synth_PlsX-like.
    [Graphical view]
    PfamiPF02504. FA_synthesis. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002465. Phsphlp_syn_PlsX. 1 hit.
    TIGRFAMsiTIGR00182. plsX. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O24993-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIVIDLMGA DHGVLPVIEG VSRALENKSF STVLVGDKDK ATPFISKELA    50
    SKVEMIHTQD YIKMEEAATE AIKRKESSIY LGMDILKNGA DALISAGHSG 100
    ATMGLATLRL GRIKGVERPA ICTLMPSVGK RPSVLLDAGA NTDCKPEYLI 150
    DFALMGYEYA KSVLHYDSPK VGLLSNGEED IKGNMLVKET HKMLKAYDFF 200
    YGNVEGSDIF KGVVDVVVCD GFMGNVVLKT TEGVASAIGS IFKDEIKSSF 250
    KSKMGALMLK NAFDILKQKT DYAEYGGAPL LGVNKSVIIS HGKSNARAIE 300
    CAIYQAISAV ESQVCLRITQ AFESLKPSVS QSDQQDA 337
    Length:337
    Mass (Da):36,352
    Last modified:May 30, 2000 - v2
    Checksum:i7916CD4F5911B23C
    GO

    Sequence cautioni

    The sequence AAD07269.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07269.1. Different initiation.
    PIRiA64545.
    RefSeqiNP_207000.1. NC_000915.1.
    YP_006934124.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07269; AAD07269; HP_0201.
    GeneIDi13869380.
    898919.
    KEGGiheo:C694_01000.
    hpy:HP0201.
    PATRICi20591623. VBIHelPyl33062_0211.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07269.1 . Different initiation.
    PIRi A64545.
    RefSeqi NP_207000.1. NC_000915.1.
    YP_006934124.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali O24993.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 85962.HP0201.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07269 ; AAD07269 ; HP_0201 .
    GeneIDi 13869380.
    898919.
    KEGGi heo:C694_01000.
    hpy:HP0201.
    PATRICi 20591623. VBIHelPyl33062_0211.

    Phylogenomic databases

    eggNOGi COG0416.
    KOi K03621.
    OMAi HNVMENL.
    OrthoDBi EOG68H88P.

    Enzyme and pathway databases

    UniPathwayi UPA00085 .

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    HAMAPi MF_00019. PlsX.
    InterProi IPR003664. FA_synthesis.
    IPR024084. IsoPropMal-DH-like_dom.
    IPR012281. Phospholipid_synth_PlsX-like.
    [Graphical view ]
    Pfami PF02504. FA_synthesis. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002465. Phsphlp_syn_PlsX. 1 hit.
    TIGRFAMsi TIGR00182. plsX. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiPLSX_HELPY
    AccessioniPrimary (citable) accession number: O24993
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 30, 2000
    Last modified: October 1, 2014
    This is version 83 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3