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O24933 (HRCA_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Heat-inducible transcription repressor HrcA
Gene names
Name:hrcA
Ordered Locus Names:HP_0111
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons By similarity. HAMAP MF_00081

Sequence similarities

Belongs to the HrcA family.

Sequence caution

The sequence AAD07182.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Heat-inducible transcription repressor HrcA HAMAP MF_00081
PRO_0000182483

Sequences

Sequence LengthMass (Da)Tools
O24933 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: F1A3F7001FF41F03

FASTA26630,795
        10         20         30         40         50         60 
MLRRIKVGSN LNKKESLLDA FVKTYLQILE PISSKRLKEL ADLKISCATI RNYFQILSKE 

        70         80         90        100        110        120 
GMLYQAHSSG ARLPTFKAFE NYWQKSLRFE TLKVNEKRLK SASENFGLFT LLKKPSLERL 

       130        140        150        160        170        180 
ERVIECEKRF LILDFLAFSC ALGYSVKMEK FLLELVGRSV KEVRSIAASF NALSLARQLE 

       190        200        210        220        230        240 
RLEYSNTQIT RFNLMGLKTL LNSPLFFDIL GGKVLERLSK GLHFIEPDCM LVTRPVEFQN 

       250        260 
KRMQLLCVGK LECDYEGFFQ TISEEE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000511 Genomic DNA. Translation: AAD07182.1. Different initiation.
PIRG64533.
RefSeqNP_206911.1. NC_000915.1.

3D structure databases

ProteinModelPortalO24933.
ModBaseSearch...

Protein-protein interaction databases

MINTMINT-166978.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID900159.
GenomeReviewsGene locus HP_0111 in contig AE000511_GR.
KEGGhpy:HP0111.
NMPDRfig|85962.1.peg.109.
PATRIC20591437. VBIHelPyl33062_0118.
TIGRHP_0111.

Phylogenomic databases

HOGENOMHBG501478.
OMAERVIECE.
ProtClustDBPRK03911.

Family and domain databases

HAMAPMF_00081. HrcA.
[Tree]
InterProIPR002571. WHTH_transcript_rep_HrcA.
IPR011991. WHTH_trsnscrt_rep_DNA-bd.
[Graphical view]
Gene3DG3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
KOK03705.
ProtoNetSearch...

Entry information

Entry nameHRCA_HELPY
AccessionPrimary (citable) accession number: O24933
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: January 25, 2012
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names

SIMILARITY comments

Index of protein domains and families

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