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Protein

Methyltransferase

Gene

HP_0050

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferaseImported, Transferase
LigandS-adenosyl-L-methionineCombined sources

Enzyme and pathway databases

BioCyciHPY:HP0050-MONOMER

Protein family/group databases

REBASEi56876 M1.Hpy26695ORF230P

Names & Taxonomyi

Protein namesi
Recommended name:
MethyltransferaseUniRule annotation (EC:2.1.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:HP_0050Imported
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)Imported
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiO24891
PRIDEiO24891

Interactioni

Protein-protein interaction databases

DIPiDIP-3048N
IntActiO24891 2 interactors.
MINTiO24891
STRINGi85962.HP0050

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5HEKX-ray3.00A/B/C/D1-232[»]
5HFJX-ray3.10A/B/C/D/E/F/G/H1-232[»]
ProteinModelPortaliO24891
SMRiO24891
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 227N6_N4_MtaseInterPro annotationAdd BLAST205

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni8 – 9S-adenosyl-L-methionine bindingCombined sources2
Regioni29 – 31S-adenosyl-L-methionine bindingCombined sources3
Regioni165 – 172S-adenosyl-L-methionine bindingCombined sources8
Regioni198 – 200S-adenosyl-L-methionine bindingCombined sources3
Regioni216 – 217S-adenosyl-L-methionine bindingCombined sources2

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108I7A Bacteria
COG0863 LUCA
KOiK00571
OMAiEFALWAV

Family and domain databases

InterProiView protein in InterPro
IPR002941 DNA_methylase_N4/N6
IPR002052 DNA_methylase_N6_adenine_CS
IPR001091 RM_Methylase
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01555 N6_N4_Mtase, 1 hit
PRINTSiPR00508 S21N4MTFRASE
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

O24891-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQIYHADAF EIIKDFYQQN LKVDAIITDP PYNISVKNNF PTLKSAKRQG
60 70 80 90 100
IDFGEWDKNF KLLEWIARYA PLVNPNGCMV IFCSYRFISY IADFLEENGF
110 120 130 140 150
VVKDFIQWVK NNPMPRNIHR RYVQDTEFAL WAVKKKAKWV FNKPKNEKYL
160 170 180 190 200
RPLILKSPVV SGLEKTKHPT QKSLALMEKI ISIHTNPNDI VLDPFMGSGT
210 220 230
TGLACKNLER NFIGIESEKE YFQTAKKRLN LF
Length:232
Mass (Da):27,103
Last modified:January 1, 1998 - v1
Checksum:i436D4021CF85F9AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA Translation: AAD07116.1
PIRiB64526
RefSeqiNP_206851.1, NC_000915.1
WP_000614886.1, NC_018939.1

Genome annotation databases

EnsemblBacteriaiAAD07116; AAD07116; HP_0050
GeneIDi899178
KEGGiheo:C694_00230
hpy:HP0050
PATRICifig|85962.47.peg.51

Similar proteinsi

Entry informationi

Entry nameiO24891_HELPY
AccessioniPrimary (citable) accession number: O24891
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported