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Reviewed, UniProtKB/Swiss-Prot O24872 (BIOD_HELPY)

Last modified November 3, 2009. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Dethiobiotin synthetase
    EC=6.3.3.3
Alternative name(s):
    Dethiobiotin synthase
    DTB synthetase
      Short name=DTBS
Gene names
Name: bioD
Ordered Locus Names: HP_0029
OrganismHelicobacter pylori (Campylobacter pylori) [Complete proteome] [HAMAP]
Taxonomic identifier210 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. HAMAP MF_00336

Cofactor

Magnesium By similarity.

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. HAMAP MF_00336

Sequence similarities

Belongs to the dethiobiotin synthetase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 218218Dethiobiotin synthetase HAMAP MF_00336
PRO_0000187971

Regions

Nucleotide binding6 – 149ATP By similarity

Secondary structure

........................................ 218
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O24872-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: C818F3D3A88C6015

FASTA21824,407
        10         20         30         40         50         60 
MLFISATNTN AGKTTCARLL AQYCNACGVK TILLKPIETG VNDAINHSSD AHLFLQDNRL 

        70         80         90        100        110        120 
LDRSLTLKDI SFYRYHKVSA PLIAQQEEDP NAPIDTDNLT QRLHNFTKTY DLVIVEGAGG 

       130        140        150        160        170        180 
LCVPITLEEN MLDFALKLKA KMLLISHDNL GLINDCLLND FLLKSHQLDY KIAINLKGNN 

       190        200        210 
TAFHSISLPY IELFNTRSNN PIVIFQQSLK VLMSFALK 

« Hide

Cross-references

Sequence databases

AE000511 Genomic DNA. Translation: AAD07100.1.
PIRE64523.
RefSeqNP_206831.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
2QMOX-ray1.47A1-218[»]
ModBaseSearch...

Genome annotation databases

GeneID899125.
GenomeReviewsGene locus HP_0029 in contig AE000511_GR.
KEGGhpy:HP0029.
NMPDRfig|85962.1.peg.29.
TIGRHP_0029.

Phylogenomic databases

HOGENOMO24872.
OMAMLFISAT

Enzyme and pathway databases

BRENDA6.3.3.3. 1131.

Family and domain databases

HAMAPMF_00336.
[Tree]
InterProIPR004472. BioD_synth.
[Graphical view]
PIRSFPIRSF006755. DTB_synth. 1 hit.
TIGRFAMsTIGR00347. bioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBIOD_HELPY
AccessionPrimary (citable) accession number: O24872
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: November 3, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents