O24849 (MTGA_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Monofunctional biosynthetic peptidoglycan transglycosylase
Short name=Monofunctional TGase
EC=2.4.2.-

Gene names

Name:	mtgA
Ordered Locus Names:	ACIAD1061

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation By similarity. HAMAP MF_00766
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00766
Subcellular location	Cell membrane; Single-pass membrane protein Potential HAMAP MF_00766.
Sequence similarities	Belongs to the glycosyltransferase 51 family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan-based cell wall Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transferase activity, transferring pentosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 224	224	Monofunctional biosynthetic peptidoglycan transglycosylase HAMAP MF_00766		PRO_0000083114
Regions
	Transmembrane	9 – 29	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	O24849 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: F1E5F114FC14E2FE	FASTA	224	26,713
	10 20 30 40 50 60 MKRFIVRAVL ILVSFVLLIQ LWIFCSLAWW RTHPVETTMF MRLDYWSDSS KPIQQQWRDY 70 80 90 100 110 120 DEISDNFKKA VVAAEDGKFV HHHGFDWEGI QYALEKNEKS GEVVNGGSTI SQQLAKNLFL 130 140 150 160 170 180 YNQRSLIRKG QEAIATWMME RMWSKQRILE VYMNSVQFGD HLYGVEAASH YYFHRSAQNL 190 200 210 220 TRDQAAFLAA LLPNPKYYQE NRNDPRFKFK KRFTLKYMRY SEIP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1." Geissdoerfer W., Frosch C.S., Haspel G., Ehrt S., Hillen W. Microbiology 141:1425-1432(1995) [PubMed: 7670642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Nucleotide sequence of a putative periplasmic Mn superoxide dismutase from Acinetobacter calcoaceticus ADP1." Geissdoerfer W., Ratajczak A., Hillen W. Gene 186:305-308(1997) [PubMed: 9074511] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ADP1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z46863 Genomic DNA. Translation: CAA86932.1. CR543861 Genomic DNA. Translation: CAG67949.1.
RefSeq	YP_045771.1. NC_005966.1.
3D structure databases
ProteinModelPortal	O24849.
ModBase	Search...
Protein-protein interaction databases
STRING	O24849.
Protein family/group databases
CAZy	GT51. Glycosyltransferase Family 51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2879151.
GenomeReviews	Gene locus ACIAD1061 in contig CR543861_GR.
KEGG	aci:ACIAD1061.
NMPDR	fig|62977.3.peg.1156.
PATRIC	20739974. VBIAciSp98416_0951.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0744.
HOGENOM	HBG685698.
OMA	TPWRKLE.
PhylomeDB	O24849.
ProtClustDB	CLSK707184.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD1061-MONOMER.
Family and domain databases
HAMAP	MF_00766. Mono_pep_trsgly. [Tree]
InterPro	IPR001264. Glyco_trans_51. IPR011812. Mono_pep_trsgly. [Graphical view]
KO	K03814.
Pfam	PF00912. Transgly. 1 hit. [Graphical view]
TIGRFAMs	TIGR02070. Mono_pep_trsgly. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MTGA_ACIAD

Accession

Primary (citable) accession number: O24849

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program