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Protein

Ribonuclease P protein component 1

Gene

rnp1

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 1UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 1UniRule annotation
Alternative name(s):
Rpp29UniRule annotation
Gene namesi
Name:rnp1UniRule annotation
Ordered Locus Names:VNG_1699C
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 123123Ribonuclease P protein component 1PRO_0000128427Add
BLAST

Proteomic databases

PaxDbiO24785.

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi64091.VNG1699C.

Structurei

3D structure databases

ProteinModelPortaliO24785.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00784. Archaea.
COG1588. LUCA.
InParanoidiO24785.
KOiK03538.
OMAiRVWHVPK.
PhylomeDBiO24785.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
HAMAPiMF_00754. RNase_P_1. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR023538. RNP1.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 2 hits.

Sequencei

Sequence statusi: Complete.

O24785-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTITPESLP RHELLGLHAR VAADTDQSRV GIAGRVVDET MQTVVLRTAS
60 70 80 90 100
GVAQVPKKGA TFEFRLTDEA AAPDNGVGTA FKPAGGETRQ TTGESVAYVT
110 120
VDGGRLLSRP ERRSENGVDS KWR
Length:123
Mass (Da):13,135
Last modified:January 1, 1998 - v1
Checksum:iE6941EE7E22237EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006961 Genomic DNA. Translation: BAA22278.1.
AE004437 Genomic DNA. Translation: AAG19944.1.
PIRiD84322.
T43824.
RefSeqiWP_010903242.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG19944; AAG19944; VNG_1699C.
GeneIDi5954228.
KEGGihal:VNG1699C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006961 Genomic DNA. Translation: BAA22278.1.
AE004437 Genomic DNA. Translation: AAG19944.1.
PIRiD84322.
T43824.
RefSeqiWP_010903242.1. NC_002607.1.

3D structure databases

ProteinModelPortaliO24785.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi64091.VNG1699C.

Proteomic databases

PaxDbiO24785.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG19944; AAG19944; VNG_1699C.
GeneIDi5954228.
KEGGihal:VNG1699C.

Phylogenomic databases

eggNOGiarCOG00784. Archaea.
COG1588. LUCA.
InParanoidiO24785.
KOiK03538.
OMAiRVWHVPK.
PhylomeDBiO24785.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
HAMAPiMF_00754. RNase_P_1. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR023538. RNP1.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiRNP1_HALSA
AccessioniPrimary (citable) accession number: O24785
Secondary accession number(s): Q9HPC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.