Reviewed, UniProtKB/Swiss-Prot O24785 (RNP1_HALSA)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	VNG_1699C

Organism

Halobacterium salinarium (Halobacterium halobium) [Complete proteome] [HAMAP]

Taxonomic identifier

2242 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	123 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 123	123	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_0000128427

Sequences

	Sequence		Length	Mass (Da)
	O24785-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: E6941EE7E22237EB	FASTA	123	13,135
	10 20 30 40 50 60 MTTITPESLP RHELLGLHAR VAADTDQSRV GIAGRVVDET MQTVVLRTAS GVAQVPKKGA 70 80 90 100 110 120 TFEFRLTDEA AAPDNGVGTA FKPAGGETRQ TTGESVAYVT VDGGRLLSRP ERRSENGVDS KWR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Organization and nucleotide sequences of ten ribosomal protein genes from the region equivalent to the S10 operon in the archaebacterium, Halobacterium halobium." Miyokawa T., Urayama T., Shimooka K., Itoh T. Biochem. Mol. Biol. Int. 39:1209-1220(1996) [PubMed: 8876975] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Genome sequence of Halobacterium species NRC-1." Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K. , Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S. Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000) [PubMed: 11016950] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700922 / JCM 11081 / NRC-1.
[3]	"Ribosomal protein gene cluster of Halobacterium halobium: nucleotide sequence of the genes coding for S3 and L29 equivalent ribosomal proteins." Spiridonova V.A., Akhmanova A.S., Kagramanova V.K., Koepke A.K.E., Mankin A.S. Can. J. Microbiol. 35:153-159(1989) [PubMed: 2470481] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-84.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB006961 Genomic DNA. Translation: BAA22278.1. AE004437 Genomic DNA. Translation: AAG19944.1.
PIR	D84322. T43824.
RefSeq	NP_280464.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1448245.
GenomeReviews	Gene locus VNG_1699C in contig AE004437_GR.
KEGG	hal:VNG1699C.
NMPDR	fig|64091.1.peg.1486.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O24785.
OMA	PERRIGM.
Enzyme and pathway databases
BioCyc	HSP64091:VNG1699C-MON.
BRENDA	3.1.26.5. 141893.
Family and domain databases
HAMAP	MF_00754. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29-sub_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProDom	PD009163. UPF0086. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00538. POP4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP1_HALSA

Accession

Primary (citable) accession number: O24785
Secondary accession number(s): Q9HPC6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	November 3, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)