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O24785

- RNP1_HALSA

UniProt

O24785 - RNP1_HALSA

Protein

Ribonuclease P protein component 1

Gene

rnp1

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. mRNA cleavage Source: InterPro
    2. rRNA processing Source: InterPro
    3. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 1UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 1UniRule annotation
    Alternative name(s):
    Rpp29UniRule annotation
    Gene namesi
    Name:rnp1UniRule annotation
    Ordered Locus Names:VNG_1699C
    OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
    Taxonomic identifieri64091 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
    ProteomesiUP000000554: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease MRP complex Source: InterPro
    3. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 123123Ribonuclease P protein component 1PRO_0000128427Add
    BLAST

    Proteomic databases

    PaxDbiO24785.

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi64091.VNG1699C.

    Structurei

    3D structure databases

    ProteinModelPortaliO24785.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1588.
    KOiK03538.
    OMAiPERRIGM.
    PhylomeDBiO24785.

    Family and domain databases

    Gene3Di2.30.30.210. 1 hit.
    HAMAPiMF_00754. RNase_P_1.
    InterProiIPR002730. RNase_P/MRP_p29.
    IPR023538. RNase_P_comp-1.
    IPR023534. Rof/RNase_P-like.
    [Graphical view]
    PfamiPF01868. UPF0086. 1 hit.
    [Graphical view]
    SMARTiSM00538. POP4. 1 hit.
    [Graphical view]
    SUPFAMiSSF101744. SSF101744. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    O24785-1 [UniParc]FASTAAdd to Basket

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    MTTITPESLP RHELLGLHAR VAADTDQSRV GIAGRVVDET MQTVVLRTAS    50
    GVAQVPKKGA TFEFRLTDEA AAPDNGVGTA FKPAGGETRQ TTGESVAYVT 100
    VDGGRLLSRP ERRSENGVDS KWR 123
    Length:123
    Mass (Da):13,135
    Last modified:January 1, 1998 - v1
    Checksum:iE6941EE7E22237EB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB006961 Genomic DNA. Translation: BAA22278.1.
    AE004437 Genomic DNA. Translation: AAG19944.1.
    PIRiD84322.
    T43824.
    RefSeqiNP_280464.1. NC_002607.1.
    WP_010903242.1. NC_002607.1.

    Genome annotation databases

    EnsemblBacteriaiAAG19944; AAG19944; VNG_1699C.
    GeneIDi1448245.
    KEGGihal:VNG1699C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB006961 Genomic DNA. Translation: BAA22278.1 .
    AE004437 Genomic DNA. Translation: AAG19944.1 .
    PIRi D84322.
    T43824.
    RefSeqi NP_280464.1. NC_002607.1.
    WP_010903242.1. NC_002607.1.

    3D structure databases

    ProteinModelPortali O24785.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 64091.VNG1699C.

    Proteomic databases

    PaxDbi O24785.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG19944 ; AAG19944 ; VNG_1699C .
    GeneIDi 1448245.
    KEGGi hal:VNG1699C.

    Phylogenomic databases

    eggNOGi COG1588.
    KOi K03538.
    OMAi PERRIGM.
    PhylomeDBi O24785.

    Family and domain databases

    Gene3Di 2.30.30.210. 1 hit.
    HAMAPi MF_00754. RNase_P_1.
    InterProi IPR002730. RNase_P/MRP_p29.
    IPR023538. RNase_P_comp-1.
    IPR023534. Rof/RNase_P-like.
    [Graphical view ]
    Pfami PF01868. UPF0086. 1 hit.
    [Graphical view ]
    SMARTi SM00538. POP4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF101744. SSF101744. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Organization and nucleotide sequences of ten ribosomal protein genes from the region equivalent to the S10 operon in the archaebacterium, Halobacterium halobium."
      Miyokawa T., Urayama T., Shimooka K., Itoh T.
      Biochem. Mol. Biol. Int. 39:1209-1220(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700922 / JCM 11081 / NRC-1.
    3. "Ribosomal protein gene cluster of Halobacterium halobium: nucleotide sequence of the genes coding for S3 and L29 equivalent ribosomal proteins."
      Spiridonova V.A., Akhmanova A.S., Kagramanova V.K., Koepke A.K.E., Mankin A.S.
      Can. J. Microbiol. 35:153-159(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-84.

    Entry informationi

    Entry nameiRNP1_HALSA
    AccessioniPrimary (citable) accession number: O24785
    Secondary accession number(s): Q9HPC6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3