O24641 (O24641_ANACO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Bromelain EMBL BAA21848.1 Submitted name: FB31 EMBL BAA22543.1
Organism	Ananas comosus (Pineapple) (Ananas ananas) EMBL BAA22543.1
Taxonomic identifier	4615 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Bromeliaceae › Ananas

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase C1 family. RuleBase RU004043

Ontologies

Keywords
Domain	Signal EMBL BAA22543.1
Molecular function	Hydrolase Protease Thiol protease SAAS SAAS013201
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	cysteine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential EMBL BAA22543.1
	Chain	25 – 352	328	Potential EMBL BAA22543.1		PRO_5000139850
	Chain	123 – 340	218	FB31 (FB13) EMBL BAA22543.1		PRO_5000139851
	Chain	123 – 340	218	bromelain EMBL BAA21848.1		PRO_5000139626

Sequences

	Sequence		Length	Mass (Da)
	O24641 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 5969AAC09EB3D367	FASTA	352	38,823
	10 20 30 40 50 60 MASKVQLVFL FLFLCVMWAS PSAASRDEPS DPMMKRFEEW MAEYGRVYKD NDEKMRRFQI 70 80 90 100 110 120 FKNNVNHIET FNNRNGNSYT LGINKFTDMT NNEFVAQYTG GISRPLNIEK EPVVSFDDVN 130 140 150 160 170 180 ISAVGQSIDW RDYGAVTEVK DQNPCGSCWA FSAIATVEGI YKIVTGYLVS LSEQEVLDCA 190 200 210 220 230 240 VSNGCDGGFV DNAYDFIISN NGVASEADYP YQAYQGDCAA NSWPNSAYIT GYSYVRSNDE 250 260 270 280 290 300 SSMKYAVWNQ PIAAAIDASG DNFQYYNGGV FSGPCGTSLN HAITIIGYGQ DSSGTQYWIV 310 320 330 340 350 KNSWGSSWGE RGYIRMARGV SSSGLCGIAM DPLYPTLQSG ANVAVIKMVS KT

References

[1]	"Cloning and sequencing of fruit bromelain." Muta E., Aramaki H., Takata Y., Kono A., Okamoto Y., Ota S. Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Fruit EMBL BAA21848.1.
[2]	"Cloning and sequencing of cysteine proteinases in Ananas comosus." Muta E., Okamoto Y., Ota S. Submitted (OCT-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Fruit EMBL BAA22543.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D14058 mRNA. Translation: BAA21848.1. D38531 mRNA. Translation: BAA22543.1.
PIR	T10501.
3D structure databases
HSSP	HSSP built from PDB template 1S4V based on UniProtKB O65039.
ProteinModelPortal	O24641.
SMR	O24641. Positions 125-339.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR025661. Pept_asp_AS. IPR000169. Pept_cys_AS. IPR025660. Pept_his_AS. IPR013128. Peptidase_C1A. IPR000668. Peptidase_C1A_C. IPR013201. Prot_inhib_I29. [Graphical view]
PANTHER	PTHR12411. PTHR12411. 1 hit.
Pfam	PF08246. Inhibitor_I29. 1 hit. PF00112. Peptidase_C1. 1 hit. [Graphical view]
PRINTS	PR00705. PAPAIN.
SMART	SM00848. Inhibitor_I29. 1 hit. SM00645. Pept_C1. 1 hit. [Graphical view]
PROSITE	PS00640. THIOL_PROTEASE_ASN. 1 hit. PS00139. THIOL_PROTEASE_CYS. 1 hit. PS00639. THIOL_PROTEASE_HIS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O24641_ANACO

Accession

Primary (citable) accession number: O24641

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	October 3, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)