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Protein

RNA polymerase sigma factor sigC

Gene

SIGC

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi531 – 550H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

  • bacterial sigma factor activity Source: TAIR
  • DNA binding Source: UniProtKB-KW
  • DNA binding transcription factor activity Source: InterPro
  • DNA-directed 5'-3' RNA polymerase activity Source: TAIR
  • plastid sigma factor activity Source: UniProtKB

GO - Biological processi

  • cellular response to light stimulus Source: UniProtKB
  • DNA-templated transcription, initiation Source: UniProtKB
  • regulation of RNA biosynthetic process Source: UniProtKB

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor sigC
Short name:
Sigma factor C
Short name:
Sigma-C
Alternative name(s):
RNA polymerase sigma factor sig3
Short name:
Atsig3
Short name:
Sigma factor 3
Gene namesi
Name:SIGC
Synonyms:SIG3
Ordered Locus Names:At3g53920
ORF Names:F5K20.220
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G53920
TAIRilocus:2084420 AT3G53920

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 32ChloroplastSequence analysisAdd BLAST32
ChainiPRO_000041809533 – 571RNA polymerase sigma factor sigCAdd BLAST539

Proteomic databases

PaxDbiO24621

PTM databases

iPTMnetiO24621

Expressioni

Tissue specificityi

Highly expressed in leaves, to a lower extent in cotyledons, and barely expressed in roots. Present in seeds, seedlings and etiolated plantlets.4 Publications

Inductioni

Slightly induced by blue light, especially after dark adaptation.5 Publications

Gene expression databases

ExpressionAtlasiO24621 baseline and differential
GenevisibleiO24621 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G53920.1

Structurei

3D structure databases

ProteinModelPortaliO24621
SMRiO24621
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi360 – 373Polymerase core bindingAdd BLAST14

Sequence similaritiesi

Belongs to the sigma-70 factor family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IGEE Eukaryota
COG0568 LUCA
HOGENOMiHOG000005804
InParanoidiO24621
KOiK03093
OMAiNISGVCV
OrthoDBiEOG093607FH
PhylomeDBiO24621

Family and domain databases

Gene3Di1.10.10.102 hits
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR016262 RNA_pol_sigma_SigB/C/D/F
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PIRSFiPIRSF000767 RNA_pol_sigma_SigB/C/D, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 1 hit
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02937 sigma70-ECF, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O24621-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASFNSFPIP KQIVGSSSSS SSSTSRPRIL VRSSLTSSMT STNSMLVFVH
60 70 80 90 100
PHPLIKHWLS LLRSDQTSFP IFVRIPMTSV VATRWSFLSS VKEESRIYQN
110 120 130 140 150
DSLKACGCAS VSPYTAQNNV YVELKDPKEN IGVGSAERSY SSRSMLQYNL
160 170 180 190 200
LAKNLLALEE TFVALDSVRM ERDIMLQMGK LGAAELFKTC LSRYRGSSIT
210 220 230 240 250
SCLSDTTELV DTTPNQQVFV SSRRKVKKKA RRSSVTAENG DQSSLPIGLR
260 270 280 290 300
TTWNNIDVPR VRRPPKYRKK RERISRNETE MSTGVKIVAD MERIRTQLEE
310 320 330 340 350
ESGKVASLSC WAAAAGMNEK LLMRNLHYGW YCRDELVKST RSLVLFLARN
360 370 380 390 400
YRGLGIAHED LIQAGYVGVL QGAERFDHTR GYKFSTYVQY WIRKSMSTMV
410 420 430 440 450
SRHARGVHIP SSIIRTINHI QKARKTLKTS HGIKYAADEE IAKLTGHSVK
460 470 480 490 500
KIRAANQCLK VVGSIDKKVG DCFTTKFLEF TPDTTMESPE EAVMRQSARR
510 520 530 540 550
DIHDLLEGLE PREKQVMVLR YGLQDYRPKS LEEIGKLLKV SKEWIRKIER
560 570
RAMAKLRDQP NAEDLRYYLN Q
Length:571
Mass (Da):64,906
Last modified:January 1, 1998 - v1
Checksum:i7F1A1651D2B4D1DF
GO

Sequence cautioni

The sequence AAM91534 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti354L → M in BAA22215 (PubMed:9405719).Curated1
Sequence conflicti538L → F in BAA22215 (PubMed:9405719).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89994 mRNA Translation: BAA22530.1
AB019944 Genomic DNA Translation: BAA82450.1
AB004822 mRNA Translation: BAA22215.1
AF015544 mRNA Translation: AAB69386.1
AL132960 Genomic DNA Translation: CAB88354.1
CP002686 Genomic DNA Translation: AEE79159.1
BT030362 mRNA Translation: ABO38775.1
AY128331 mRNA Translation: AAM91534.1 Different initiation.
PIRiT45932
RefSeqiNP_190960.1, NM_115252.3
UniGeneiAt.21270

Genome annotation databases

EnsemblPlantsiAT3G53920.1; AT3G53920.1; AT3G53920
GeneIDi824559
GrameneiAT3G53920.1; AT3G53920.1; AT3G53920
KEGGiath:AT3G53920

Similar proteinsi

Entry informationi

Entry nameiSIGC_ARATH
AccessioniPrimary (citable) accession number: O24621
Secondary accession number(s): O22058, Q8L7P7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2012
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome