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Protein

Non-symbiotic hemoglobin 2

Gene

AHB2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule. Has a low affinity for O2.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi66Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi101Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

  • heme binding Source: InterPro
  • metal ion binding Source: UniProtKB-KW
  • oxygen binding Source: InterPro
  • oxygen carrier activity Source: TAIR

GO - Biological processi

  • fatty acid metabolic process Source: TAIR
  • triglyceride biosynthetic process Source: TAIR

Keywordsi

LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-symbiotic hemoglobin 2
Alternative name(s):
ARAth GLB2
Short name:
Hb2
Gene namesi
Name:AHB2
Synonyms:GLB2
Ordered Locus Names:At3g10520
ORF Names:F13M14.20, F18K10.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G10520
TAIRilocus:2075780 AT3G10520

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001930121 – 158Non-symbiotic hemoglobin 2Add BLAST158

Proteomic databases

PaxDbiO24521

Expressioni

Tissue specificityi

Expressed in rosette leaves but not in roots.

Inductioni

By low temperature but not by low oxygen levels, dehydration, heat shock, wounding or oxidative stress.

Gene expression databases

ExpressionAtlasiO24521 baseline and differential
GenevisibleiO24521 AT

Interactioni

Subunit structurei

Unable to dimerize.Curated

Protein-protein interaction databases

STRINGi3702.AT3G10520.1

Structurei

3D structure databases

ProteinModelPortaliO24521
SMRiO24521
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the plant globin family.Curated

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
HOGENOMiHOG000233101
InParanoidiO24521
OMAiDEMKEAW
OrthoDBiEOG09360PFS
PhylomeDBiO24521

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR001032 Leghaemoglobin
IPR019824 Leghaemoglobin_Fe_BS
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00188 PLANTGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit
PS00208 PLANT_GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

O24521-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEIGFTEKQ EALVKESWEI LKQDIPKYSL HFFSQILEIA PAAKGLFSFL
60 70 80 90 100
RDSDEVPHNN PKLKAHAVKV FKMTCETAIQ LREEGKVVVA DTTLQYLGSI
110 120 130 140 150
HLKSGVIDPH FEVVKEALLR TLKEGLGEKY NEEVEGAWSQ AYDHLALAIK

TEMKQEES
Length:158
Mass (Da):17,871
Last modified:January 1, 1998 - v1
Checksum:i9E3E145432E0BEA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U94999 Genomic DNA Translation: AAB82770.1
AC011560 Genomic DNA Translation: AAG51381.1
AC013428 Genomic DNA Translation: AAF76353.1
CP002686 Genomic DNA Translation: AEE74919.1
AY087650 mRNA Translation: AAM65188.1
RefSeqiNP_187663.1, NM_111887.3
UniGeneiAt.48644

Genome annotation databases

EnsemblPlantsiAT3G10520.1; AT3G10520.1; AT3G10520
GeneIDi820216
GrameneiAT3G10520.1; AT3G10520.1; AT3G10520
KEGGiath:AT3G10520

Similar proteinsi

Entry informationi

Entry nameiHBL2_ARATH
AccessioniPrimary (citable) accession number: O24521
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health