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Protein

Ras-related protein RABE1a

Gene

RABE1A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in membrane trafficking from the Golgi to the plasma membrane.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 29GTPBy similarity8
Nucleotide bindingi70 – 74GTPBy similarity5
Nucleotide bindingi128 – 131GTPBy similarity4
Nucleotide bindingi159 – 160GTPBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-6798695. Neutrophil degranulation.
R-ATH-8873719. RAB geranylgeranylation.
R-ATH-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABE1a
Short name:
AtRABE1a
Alternative name(s):
Ras-related protein Rab8B
Short name:
AtRab8B
Gene namesi
Name:RABE1A
Synonyms:RAB8, RAB8B
Ordered Locus Names:At3g53610
ORF Names:F4P12.310
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G53610.
TAIRilocus:2084056. AT3G53610.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR
  • Golgi membrane Source: UniProtKB-SubCell
  • plasma membrane Source: TAIR

Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004073321 – 216Ras-related protein RABE1aAdd BLAST216

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi213S-geranylgeranyl cysteineBy similarity1
Lipidationi214S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

PaxDbiO24466.
PRIDEiO24466.

Expressioni

Inductioni

By ethylene.1 Publication

Gene expression databases

ExpressionAtlasiO24466. baseline and differential.
GenevisibleiO24466. AT.

Interactioni

Subunit structurei

Interacts with PI5K2.1 Publication

Protein-protein interaction databases

BioGridi9846. 8 interactors.
IntActiO24466. 5 interactors.
STRINGi3702.AT3G53610.1.

Structurei

3D structure databases

ProteinModelPortaliO24466.
SMRiO24466.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi44 – 52Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
HOGENOMiHOG000233968.
InParanoidiO24466.
KOiK07901.
OMAiNPQGSNQ.
OrthoDBiEOG09360P8P.
PhylomeDBiO24466.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51419. RAB. 1 hit.

Sequencei

Sequence statusi: Complete.

O24466-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPPARARA DYDYLIKLLL IGDSGVGKSC LLLRFSDGSF TTSFITTIGI
60 70 80 90 100
DFKIRTIELD GKRIKLQIWD TAGQERFRTI TTAYYRGAMG ILLVYDVTDE
110 120 130 140 150
SSFNNIRNWI RNIEQHASDS VNKILVGNKA DMDESKRAVP KSKGQALADE
160 170 180 190 200
YGMKFFETSA KTNLNVEEVF FSIAKDIKQR LADTDARAEP QTIKINQSDQ
210
GAGTSQATQK SACCGT
Length:216
Mass (Da):23,939
Last modified:January 1, 1998 - v1
Checksum:i1648E45B29D4EEB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82434 mRNA. Translation: AAB65088.1.
AL132966 Genomic DNA. Translation: CAB67668.1.
CP002686 Genomic DNA. Translation: AEE79116.1.
CP002686 Genomic DNA. Translation: AEE79117.1.
CP002686 Genomic DNA. Translation: AEE79118.1.
BT004779 mRNA. Translation: AAO44045.1.
AK228083 mRNA. Translation: BAF00042.1.
AK230120 mRNA. Translation: BAF01936.1.
AY086756 mRNA. Translation: AAM63807.1.
PIRiT45901.
RefSeqiNP_001078278.1. NM_001084809.2.
NP_190929.1. NM_115221.4.
NP_850696.1. NM_180365.3.
UniGeneiAt.10020.

Genome annotation databases

EnsemblPlantsiAT3G53610.1; AT3G53610.1; AT3G53610.
AT3G53610.2; AT3G53610.2; AT3G53610.
AT3G53610.3; AT3G53610.3; AT3G53610.
GeneIDi824529.
GrameneiAT3G53610.1; AT3G53610.1; AT3G53610.
AT3G53610.2; AT3G53610.2; AT3G53610.
AT3G53610.3; AT3G53610.3; AT3G53610.
KEGGiath:AT3G53610.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRAE1A_ARATH
AccessioniPrimary (citable) accession number: O24466
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: January 1, 1998
Last modified: July 5, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families