O24319 (O24319_PHAVU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Purple acid phosphatase EMBL CAA04644.1
EC=3.1.3.2 EMBL CAA04644.1

Gene names

Name:

pap EMBL CAA04644.1

Organism

Phaseolus vulgaris (Kidney bean) (French bean) EMBL CAA04644.1

Taxonomic identifier

3885 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Phaseolus

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Signal EMBL CAA04644.1
Molecular function	Hydrolase EMBL CAA04644.1
Technical term	3D-structure PDB 4DSY PDB 4DHL PDB 4DT2
Gene Ontology (GO)
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 27	27	Potential EMBL CAA04644.1
	Chain	28 – 459	432	purple acid phosphatase EMBL CAA04644.1		PRO_5000064272

Sequences

	Sequence		Length	Mass (Da)
	O24319 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: CC379B7C1AE4D21A	FASTA	459	52,857
	10 20 30 40 50 60 MGVVKGLLAL ALVLNVVVVS NGGKSSNFVR KTNKNRDMPL DSDVFRVPPG YNAPQQVHIT 70 80 90 100 110 120 QGDLVGRAMI ISWVTMDEPG SSAVRYWSEK NGRKRIAKGK MSTYRFFNYS SGFIHHTTIR 130 140 150 160 170 180 KLKYNTKYYY EVGLRNTTRR FSFITPPQTG LDVPYTFGLI GDLGQSFDSN TTLSHYELSP 190 200 210 220 230 240 KKGQTVLFVG DLSYADRYPN HDNVRWDTWG RFTERSVAYQ PWIWTAGNHE IEFAPEINET 250 260 270 280 290 300 EPFKPFSYRY HVPYEASQST SPFWYSIKRA SAHIIVLSSY SAYGRGTPQY TWLKKELRKV 310 320 330 340 350 360 KRSETPWLIV LMHSPLYNSY NHHFMEGEAM RTKFEAWFVK YKVDVVFAGH VHAYERSERV 370 380 390 400 410 420 SNIAYKITNG LCTPVKDQSA PVYITIGDAG NYGVIDSNMI QPQPEYSAFR EASFGHGMFD 430 440 450 IKNRTHAHFS WNRNQDGVAV EADSVWFFNR HWYPVDDST

References

[1]	"Heterologous expression and characterization of recombinant purple acid phosphatase from red kidney bean." Vogel A., Borchers T., Marcus K., Meyer H.E., Krebs B., Spener F. Arch. Biochem. Biophys. 401:164-172(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Seed EMBL CAA04644.1.
[2]	"Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics." Feder D., Hussein W.M., Clayton D.J., Kan M.W., Schenk G., McGeary R.P., Guddat L.W. Chem. Biol. Drug Des. 80:665-674(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 34-459.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AJ001270 mRNA. Translation: CAA04644.1.

PIR

S51031. T51097.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4DHL	X-ray	2.30	A/B/C/D	34-459	[»]
4DSY	X-ray	2.30	A/B/C/D	34-459	[»]
4DT2	X-ray	2.70	A/B/C/D	34-459	[»]

ProteinModelPortal

O24319.

SMR

O24319. Positions 36-459.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.60.40.380. 1 hit.

InterPro

IPR004843. Metallo_PEstase_dom.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]

Pfam

PF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
[Graphical view]

SUPFAM

SSF49363. Purple_Pase_N. 1 hit.

ProtoNet

Search...

Entry information

Entry name

O24319_PHAVU

Accession

Primary (citable) accession number: O24319

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	May 29, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)