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Protein

Phosphoinositide phospholipase C

Gene

plc

Organism
Pisum sativum (Garden pea)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation, TransducerSAAS annotation

Keywords - Biological processi

Lipid degradationUniRule annotation, Lipid metabolism

Enzyme and pathway databases

BRENDAi3.1.4.11. 4872.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoinositide phospholipase CUniRule annotation (EC:3.1.4.11UniRule annotation)
Gene namesi
Name:plcImported
OrganismiPisum sativum (Garden pea)Imported
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliO24297.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini110 – 254145PI-PLC X-boxInterPro annotationAdd
BLAST
Domaini359 – 44587PI-PLC Y-boxInterPro annotationAdd
BLAST
Domaini452 – 559108C2InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 C2 domain.UniRule annotation
Contains 1 PI-PLC X-box domain.UniRule annotation
Contains 1 PI-PLC Y-box domain.UniRule annotation

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
2.60.40.150. 1 hit.
3.20.20.190. 2 hits.
InterProiIPR000008. C2_dom.
IPR011992. EF-hand-dom_pair.
IPR001192. PI-PLC_fam.
IPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR015359. PLC_EF-hand-like.
IPR000909. PLipase_C_PInositol-sp_X_dom.
IPR001711. PLipase_C_Pinositol-sp_Y.
[Graphical view]
PANTHERiPTHR10336. PTHR10336. 1 hit.
PfamiPF00168. C2. 1 hit.
PF09279. EF-hand_like. 1 hit.
PF00388. PI-PLC-X. 1 hit.
PF00387. PI-PLC-Y. 1 hit.
[Graphical view]
PRINTSiPR00390. PHPHLIPASEC.
SMARTiSM00239. C2. 1 hit.
SM00148. PLCXc. 1 hit.
SM00149. PLCYc. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF51695. SSF51695. 1 hit.
PROSITEiPS50004. C2. 1 hit.
PS50007. PIPLC_X_DOMAIN. 1 hit.
PS50008. PIPLC_Y_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O24297-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKQKQTYS VCFCCRRRFK LGISEAPSQI RELYHNYSDE SAIMTASHLQ
60 70 80 90 100
RFLIEVQGDE NITENEAQSI IDGHKHLSIF HRRGLNLESF FKFLFSDNNA
110 120 130 140 150
PLLASRGVHQ VMSLPLSHYY IHTGHNSYLT GNQLSSDCSD APIIVALQRG
160 170 180 190 200
VRVIELDIWP NGSKDDIEVL HGRTLTTPVA LIKCLRSIKE YAFVASEYPV
210 220 230 240 250
VITLEDHLTP DLQAKVAQMV TQTFGDILFC PSSESLKEFP SPDSLKRRII
260 270 280 290 300
ISTKPPKEYL EAKEVQEKEE LTKGKSSGDE EAWGKEVPSL RGGTISDYKN
310 320 330 340 350
NDDDDEDDLN EEEDSEEAEK SRQNGSGEYR RLIAIHAGKP KGGLVEGLKV
360 370 380 390 400
DPDKVRRLSL SESQLEKAAE TYGKEIVRFT QRNILRVYPK GTRITSSNYN
410 420 430 440 450
PLIGWMHGAQ MVAFNMQGYG RSLWLMQGMF KANGGCGFVK KPDFLLKTGP
460 470 480 490 500
NNEVFDPKAS LPLKTTLKVT VYMGEGWYYD FDHTHFDQFS PPDFYARVGI
510 520 530 540 550
AGVPFDTIMK KTKTVEDSWL PSWNEVFEFP LSVPELALLR IEVHEYDMSE
560 570 580 590
KDDFGGQTCL PVWELRTGIR AVPLHSRKGD KYNNVKLLMR FEFI
Length:594
Mass (Da):67,436
Last modified:October 1, 2002 - v2
Checksum:i2AEF1BE99EF5EB2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15253 mRNA. Translation: CAA75546.2.
PIRiT06467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15253 mRNA. Translation: CAA75546.2.
PIRiT06467.

3D structure databases

ProteinModelPortaliO24297.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi3.1.4.11. 4872.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
2.60.40.150. 1 hit.
3.20.20.190. 2 hits.
InterProiIPR000008. C2_dom.
IPR011992. EF-hand-dom_pair.
IPR001192. PI-PLC_fam.
IPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR015359. PLC_EF-hand-like.
IPR000909. PLipase_C_PInositol-sp_X_dom.
IPR001711. PLipase_C_Pinositol-sp_Y.
[Graphical view]
PANTHERiPTHR10336. PTHR10336. 1 hit.
PfamiPF00168. C2. 1 hit.
PF09279. EF-hand_like. 1 hit.
PF00388. PI-PLC-X. 1 hit.
PF00387. PI-PLC-Y. 1 hit.
[Graphical view]
PRINTSiPR00390. PHPHLIPASEC.
SMARTiSM00239. C2. 1 hit.
SM00148. PLCXc. 1 hit.
SM00149. PLCYc. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF51695. SSF51695. 1 hit.
PROSITEiPS50004. C2. 1 hit.
PS50007. PIPLC_X_DOMAIN. 1 hit.
PS50008. PIPLC_Y_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Venkataraman G., Reddy M.K., Sopory S.K.
    Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LeafImported.

Entry informationi

Entry nameiO24297_PEA
AccessioniPrimary (citable) accession number: O24297
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: October 1, 2002
Last modified: April 13, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.