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Protein

Phosphoinositide phospholipase C

Gene

plc

Organism
Pisum sativum (Garden pea)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation, TransducerSAAS annotation
Biological processLipid degradationUniRule annotationSAAS annotation, Lipid metabolism

Enzyme and pathway databases

BRENDAi3.1.4.11 4872

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoinositide phospholipase CUniRule annotation (EC:3.1.4.11UniRule annotation)
Gene namesi
Name:plcImported
OrganismiPisum sativum (Garden pea)Imported
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Subcellular locationi

Structurei

3D structure databases

ProteinModelPortaliO24297
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 254PI-PLC X-boxInterPro annotationAdd BLAST145
Domaini359 – 445PI-PLC Y-boxInterPro annotationAdd BLAST87
Domaini452 – 559C2InterPro annotationAdd BLAST108

Family and domain databases

Gene3Di2.60.40.150, 1 hit
3.20.20.190, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR011992 EF-hand-dom_pair
IPR001192 PI-PLC_fam
IPR017946 PLC-like_Pdiesterase_TIM-brl
IPR015359 PLC_EF-hand-like
IPR000909 PLipase_C_PInositol-sp_X_dom
IPR001711 PLipase_C_Pinositol-sp_Y
PANTHERiPTHR10336 PTHR10336, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF09279 EF-hand_like, 1 hit
PF00388 PI-PLC-X, 1 hit
PF00387 PI-PLC-Y, 1 hit
PRINTSiPR00390 PHPHLIPASEC
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00148 PLCXc, 1 hit
SM00149 PLCYc, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50007 PIPLC_X_DOMAIN, 1 hit
PS50008 PIPLC_Y_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

O24297-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKQKQTYS VCFCCRRRFK LGISEAPSQI RELYHNYSDE SAIMTASHLQ
60 70 80 90 100
RFLIEVQGDE NITENEAQSI IDGHKHLSIF HRRGLNLESF FKFLFSDNNA
110 120 130 140 150
PLLASRGVHQ VMSLPLSHYY IHTGHNSYLT GNQLSSDCSD APIIVALQRG
160 170 180 190 200
VRVIELDIWP NGSKDDIEVL HGRTLTTPVA LIKCLRSIKE YAFVASEYPV
210 220 230 240 250
VITLEDHLTP DLQAKVAQMV TQTFGDILFC PSSESLKEFP SPDSLKRRII
260 270 280 290 300
ISTKPPKEYL EAKEVQEKEE LTKGKSSGDE EAWGKEVPSL RGGTISDYKN
310 320 330 340 350
NDDDDEDDLN EEEDSEEAEK SRQNGSGEYR RLIAIHAGKP KGGLVEGLKV
360 370 380 390 400
DPDKVRRLSL SESQLEKAAE TYGKEIVRFT QRNILRVYPK GTRITSSNYN
410 420 430 440 450
PLIGWMHGAQ MVAFNMQGYG RSLWLMQGMF KANGGCGFVK KPDFLLKTGP
460 470 480 490 500
NNEVFDPKAS LPLKTTLKVT VYMGEGWYYD FDHTHFDQFS PPDFYARVGI
510 520 530 540 550
AGVPFDTIMK KTKTVEDSWL PSWNEVFEFP LSVPELALLR IEVHEYDMSE
560 570 580 590
KDDFGGQTCL PVWELRTGIR AVPLHSRKGD KYNNVKLLMR FEFI
Length:594
Mass (Da):67,436
Last modified:October 1, 2002 - v2
Checksum:i2AEF1BE99EF5EB2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15253 mRNA Translation: CAA75546.2
PIRiT06467

Similar proteinsi

Entry informationi

Entry nameiO24297_PEA
AccessioniPrimary (citable) accession number: O24297
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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