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O24246

- PMGI_PRUDU

UniProt

O24246 - PMGI_PRUDU

Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene
N/A
Organism
Prunus dulcis (Almond) (Amygdalus dulcis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.By similarity

    Catalytic activityi

    2-phospho-D-glycerate = 3-phospho-D-glycerate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei10 – 101Phosphoserine intermediateBy similarity
    Metal bindingi10 – 101Manganese 2By similarity
    Metal bindingi359 – 3591Manganese 1By similarity
    Metal bindingi363 – 3631Manganese 1By similarity
    Metal bindingi400 – 4001Manganese 2By similarity
    Metal bindingi401 – 4011Manganese 2By similarity
    Metal bindingi430 – 4301Manganese 1By similarity

    GO - Molecular functioni

    1. manganese ion binding Source: InterPro
    2. phosphoglycerate mutase activity Source: InterPro

    GO - Biological processi

    1. glucose catabolic process Source: InterPro
    2. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00186.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC:5.4.2.12)
    Short name:
    BPG-independent PGAM
    Short name:
    Phosphoglyceromutase
    Alternative name(s):
    PGAM-I
    OrganismiPrunus dulcis (Almond) (Amygdalus dulcis)
    Taxonomic identifieri3755 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeMaloideaeAmygdaleaePrunus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 488›4882,3-bisphosphoglycerate-independent phosphoglycerate mutasePRO_0000212112Add
    BLAST

    Proteomic databases

    PRIDEiO24246.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO24246.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.1450.10. 1 hit.
    3.40.720.10. 2 hits.
    InterProiIPR017849. Alkaline_Pase-like_a/b/a.
    IPR017850. Alkaline_phosphatase_core.
    IPR011258. BPG-indep_PGM_N.
    IPR006124. Metalloenzyme.
    IPR005995. Pgm_bpd_ind.
    [Graphical view]
    PfamiPF06415. iPGM_N. 1 hit.
    PF01676. Metalloenzyme. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001492. IPGAM. 1 hit.
    SUPFAMiSSF53649. SSF53649. 2 hits.
    SSF64158. SSF64158. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O24246-1 [UniParc]FASTAAdd to Basket

    « Hide

    LPTEDDMGNS EVGHNALGAG RIFAQGAKLV DSALETGKLY EGEGFKYIKE    50
    SFPTNTLHLI GLLSDGGVHS RLDQLLLLVK GASERGAKRI RVHILTDGRD 100
    VLDGSSVGFA ETLENYLAQL REKGVDAQIA SGGGRMYVTM DRYENDWGVV 150
    KRGWDAQVLG EAPHKFKNAV EAIKTLRQEP NTSDQYLPPF VIVDENGKPV 200
    GPIVDGDAVV TFNFRADRMV MIAKALEYAD FDKFDRVRFP KIRYAGMLQY 250
    DGELKLPSKY LVEPPEIDRT SGEYLTYNGV RTFACSETVK FGHVTFFWNG 300
    NRSGYFNPQM EEYVEIPSDS GITFNVQPKM KAVEIAEKGR GAILSKKFEQ 350
    VRVNLPNSDM VGHTSSIEAT VVACKAADEA VKIIIDAIEQ VGGIYVVTAD 400
    HGNAEDMVKR NKKGQPLLDK NGNIQILTSH TLQPVPIAIG GPGLAPGVQF 450
    RKDVPNGGLA NVAATVMNLH GFEAPADYET TLIEVVDN 488
    Length:488
    Mass (Da):53,395
    Last modified:January 1, 1998 - v1
    Checksum:iF103633B8FCD2D2A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75020 mRNA. Translation: CAA52928.1.
    PIRiT09138.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75020 mRNA. Translation: CAA52928.1 .
    PIRi T09138.

    3D structure databases

    ProteinModelPortali O24246.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O24246.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00186 .

    Family and domain databases

    Gene3Di 3.40.1450.10. 1 hit.
    3.40.720.10. 2 hits.
    InterProi IPR017849. Alkaline_Pase-like_a/b/a.
    IPR017850. Alkaline_phosphatase_core.
    IPR011258. BPG-indep_PGM_N.
    IPR006124. Metalloenzyme.
    IPR005995. Pgm_bpd_ind.
    [Graphical view ]
    Pfami PF06415. iPGM_N. 1 hit.
    PF01676. Metalloenzyme. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001492. IPGAM. 1 hit.
    SUPFAMi SSF53649. SSF53649. 2 hits.
    SSF64158. SSF64158. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "2,3-Bisphosphoglycerate-independent phosphoglycerate mutase is conserved among different phylogenic kingdoms."
      Grana X., Perez de la Ossa P., Broceno C., Stocker M., Garriga J., Puigdomenech P., Climent F.
      Comp. Biochem. Physiol. 112B:287-293(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Texas.
      Tissue: Root.

    Entry informationi

    Entry nameiPMGI_PRUDU
    AccessioniPrimary (citable) accession number: O24246
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3