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O24210 (PANC_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pantoate--beta-alanine ligase

EC=6.3.2.1
Alternative name(s):
Pantoate-activating enzyme
Pantothenate synthetase
Gene names
Name:PANC
Ordered Locus Names:Os03g0851800, LOC_Os03g63490
ORF Names:OSJNBa0015N08.21
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate. HAMAP-Rule MF_00158

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1. HAMAP-Rule MF_00158

Subunit structure

Homodimer Potential.

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00158.

Sequence similarities

Belongs to the pantothenate synthetase family.

Sequence caution

The sequence CAA71303.1 differs from that shown. Reason: Frameshift at several positions.

The sequence CAA71303.1 differs from that shown. Reason: Sequencing errors.

Ontologies

Keywords
   Biological processPantothenate biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processembryo development ending in seed dormancy

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

pantothenate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytosol

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

pantoate-beta-alanine ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Pantoate--beta-alanine ligase HAMAP-Rule MF_00158
PRO_0000128300

Sequences

Sequence LengthMass (Da)Tools
O24210 [UniParc].

Last modified May 30, 2006. Version 2.
Checksum: 8079519175263FDF

FASTA31334,039
        10         20         30         40         50         60 
MAAPREPEVI RDKAAMRAWS RRRRAEGKTV AVVPTMGYLH QGHLSLISAA AAAASADPVA 

        70         80         90        100        110        120 
IVVTIYVNPS QFAPSEDLAT YPSDFAGDLR KLASTGVVDA VFNPPDLYVR GAGRRGAASG 

       130        140        150        160        170        180 
GAISCLEEAA GDGHETWVRV ERLEKGMCGA SRPVFFRGVA TIVSKLFNII EPDVAVFGKK 

       190        200        210        220        230        240 
DYQQWRVICR MVRDLDFAIE IIGSEIVREA DGLAMSSRNV HLSREEREKA LSISRSLVDA 

       250        260        270        280        290        300 
RTGALKGNTD CKQIKNKIVQ TLTETGGQVD YVEIVEQESL VPVEQIDGPV VICVAAWFGK 

       310 
VRLIDNIEID TRS 

« Hide

References

« Hide 'large scale' references
[1]"The final step of pantothenate biosynthesis in higher plants: cloning and characterization of pantothenate synthetase from Lotus japonicus and Oryza sativum (rice)."
Genschel U., Powell C.A., Abell C., Smith A.G.
Biochem. J. 341:669-678(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Nipponbare.
Tissue: Seedling root.
[2]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y10253 mRNA. Translation: CAA71303.1. Sequence problems.
AC096688 Genomic DNA. Translation: AAO20059.1.
AK066656 mRNA. No translation available.
PIRT03924.
RefSeqNP_001051918.1. NM_001058453.1.
UniGeneOs.4531.

3D structure databases

ProteinModelPortalO24210.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS03T0851800-01; OS03T0851800-01; OS03G0851800.
GeneID4334806.
KEGGosa:4334806.

Organism-specific databases

GrameneO24210.

Phylogenomic databases

eggNOGCOG0414.
HOGENOMHOG000175516.
KOK01918.
OMAQKDAQQF.
ProtClustDBPLN02660.

Enzyme and pathway databases

BRENDA6.3.2.1. 4460.
UniPathwayUPA00028; UER00005.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00158. PanC.
InterProIPR003721. Pantoate_ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR21299:SF1. PTHR21299:SF1. 1 hit.
PfamPF02569. Pantoate_ligase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00018. panC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePANC_ORYSJ
AccessionPrimary (citable) accession number: O24210
Secondary accession number(s): Q851Y0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 30, 2006
Last modified: April 16, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways