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O24030

- PSA7_SOLLC

UniProt

O24030 - PSA7_SOLLC

Protein

Proteasome subunit alpha type-7

Gene

PAD1

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

    Catalytic activityi

    Cleavage of peptide bonds with very broad specificity.PROSITE-ProRule annotation

    GO - Molecular functioni

    1. threonine-type endopeptidase activity Source: UniProtKB-KW

    GO - Biological processi

    1. ubiquitin-dependent protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Threonine protease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proteasome subunit alpha type-7 (EC:3.4.25.1)
    Alternative name(s):
    20S proteasome alpha subunit D
    20S proteasome subunit alpha-4
    Gene namesi
    Name:PAD1
    Synonyms:PSR5
    OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
    Taxonomic identifieri4081 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
    ProteomesiUP000004994: Unplaced

    Subcellular locationi

    Cytoplasm By similarity. Nucleus By similarity

    GO - Cellular componenti

    1. chloroplast Source: EnsemblPlants/Gramene
    2. cytosolic ribosome Source: EnsemblPlants/Gramene
    3. nucleus Source: UniProtKB-SubCell
    4. phragmoplast Source: EnsemblPlants/Gramene
    5. proteasome core complex, alpha-subunit complex Source: InterPro
    6. spindle Source: EnsemblPlants/Gramene
    7. vacuolar membrane Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Cytoplasm, Nucleus, Proteasome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 259259Proteasome subunit alpha type-7PRO_0000124162Add
    BLAST

    Proteomic databases

    PRIDEiO24030.

    Interactioni

    Subunit structurei

    The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO24030.
    SMRiO24030. Positions 4-231.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase T1A family.PROSITE-ProRule annotation

    Phylogenomic databases

    KOiK02731.

    Family and domain databases

    Gene3Di3.60.20.10. 1 hit.
    InterProiIPR029055. Ntn_hydrolases_N.
    IPR000426. Proteasome_asu_N.
    IPR023332. Proteasome_suA-type.
    IPR001353. Proteasome_sua/b.
    [Graphical view]
    PfamiPF00227. Proteasome. 1 hit.
    PF10584. Proteasome_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00948. Proteasome_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF56235. SSF56235. 1 hit.
    PROSITEiPS00388. PROTEASOME_ALPHA_1. 1 hit.
    PS51475. PROTEASOME_ALPHA_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O24030-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARYDRAITV FSPDGHLFQV EYAMEAVRKG NAAVGVRGTD TVVLGVEKKS    50
    TPKLQDSRSV RKIVNLDDHI ALACAGLKAD ARVLVNKARI ECQSHRLTVE 100
    DPVTVEYITR YIAGLQQKYT QSGGVRPFGL STLIIGFDPH TGVPSLYQTD 150
    PSGTFSAWKA NATGRNSNST REFLEKNYKE TSGQETVKLA IRALLEVVES 200
    GGKNIEVAVM TKEHGLKQLE EAEIDAIVAE IEAEKAAAEA AKRPHRRNLV 250
    ELKFVLNYP 259
    Length:259
    Mass (Da):28,480
    Last modified:January 1, 1998 - v1
    Checksum:i700B3638C9F0FB52
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14339 mRNA. Translation: CAA74725.1.
    PIRiT07744.
    RefSeqiNP_001234333.1. NM_001247404.1.
    UniGeneiLes.1195.

    Genome annotation databases

    GeneIDi544128.
    KEGGisly:544128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14339 mRNA. Translation: CAA74725.1 .
    PIRi T07744.
    RefSeqi NP_001234333.1. NM_001247404.1.
    UniGenei Les.1195.

    3D structure databases

    ProteinModelPortali O24030.
    SMRi O24030. Positions 4-231.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O24030.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 544128.
    KEGGi sly:544128.

    Phylogenomic databases

    KOi K02731.

    Family and domain databases

    Gene3Di 3.60.20.10. 1 hit.
    InterProi IPR029055. Ntn_hydrolases_N.
    IPR000426. Proteasome_asu_N.
    IPR023332. Proteasome_suA-type.
    IPR001353. Proteasome_sua/b.
    [Graphical view ]
    Pfami PF00227. Proteasome. 1 hit.
    PF10584. Proteasome_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00948. Proteasome_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56235. SSF56235. 1 hit.
    PROSITEi PS00388. PROTEASOME_ALPHA_1. 1 hit.
    PS51475. PROTEASOME_ALPHA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterization of PSR5, a tomato cDNA encoding a 20S subunit from the proteasome repressed by phosphate starvation."
      Ziethe K., Stenzel I., Hertel S.C., Koeck M.
      Plant Gene Register PGR98-065
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Lukullus.

    Entry informationi

    Entry nameiPSA7_SOLLC
    AccessioniPrimary (citable) accession number: O24030
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3