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Protein

13S globulin seed storage protein 1

Gene

FA02

Organism
Fagopyrum esculentum (Common buckwheat) (Polygonum fagopyrum)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Seed storage protein.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Seed storage protein, Storage protein

Names & Taxonomyi

Protein namesi
Recommended name:
13S globulin seed storage protein 1
Alternative name(s):
Legumin-like protein 1
Cleaved into the following 2 chains:
Gene namesi
Name:FA02
OrganismiFagopyrum esculentum (Common buckwheat) (Polygonum fagopyrum)
Taxonomic identifieri3617 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesPolygonaceaePolygonoideaeFagopyreaeFagopyrum

Pathology & Biotechi

Protein family/group databases

Allergomei698. Fag e 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 37735713S globulin seed storage protein 1 acidic chainBy similarityPRO_0000032003Add
BLAST
Chaini378 – 56518813S globulin seed storage protein 1 basic chainBy similarityPRO_0000032004Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi44 ↔ 77By similarity
Disulfide bondi120 ↔ 384Interchain (between acidic and basic chains)Sequence analysis

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed only in immature seeds.1 Publication

Developmental stagei

Expressed between 7 and 28 days after pollination.1 Publication

Interactioni

Subunit structurei

Hexamer; each subunit is composed of an acidic and a basic chain derived from a single precursor and linked by a disulfide bond.By similarity

Structurei

3D structure databases

ProteinModelPortaliO23878.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.10. 3 hits.
InterProiIPR006044. 11S_seedstore_pln.
IPR006045. Cupin_1.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF00190. Cupin_1. 2 hits.
[Graphical view]
PRINTSiPR00439. 11SGLOBULIN.
SMARTiSM00835. Cupin_1. 2 hits.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O23878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKLILSFS LCLMVLSCSA QLLPWRKGQR SRPHRGHQQF HHQCDVQRLT
60 70 80 90 100
ASEPSRRVRS EAGVTEIWDN DTPEFRCAGF VAVRVVIQPG GLLLPSYSNA
110 120 130 140 150
PYITFVEQGR GVQGVVVPGC PETFQSESEF EYPQSQRDQR SRQSESEESS
160 170 180 190 200
RGDQRTRQSE SEEFSRGDQR TRQSESEEFS RGDQRTRQSE SEEFSRGDQR
210 220 230 240 250
TRQSESEEFS RGDQHQKIFR IRDGDVIPSP AGVVQWTHND GDNDLISITL
260 270 280 290 300
YDANSFQNQL DGNVRNFFLA GQSKQSREDR RSQRQTREEG SDRQSRESDD
310 320 330 340 350
DEALLEANIL TGFQDEILQE IFRNVDQETI SKLRGDNDQR GFIVQARDLK
360 370 380 390 400
LRVPEEYEEE LQRERGDRKR GGSGRSNGLE QAFCNLKFKQ NVNRPSRADV
410 420 430 440 450
FNPRAGRINT VNSNNLPILE FIQLSAQHVV LYKNAILGPR WNLNAHSALY
460 470 480 490 500
VTRGEGRVQV VGDEGRSVFD DNVQRGQILV VPQGFAVVLK AGREGLEWVE
510 520 530 540 550
LKNDDNAITS PIAGKTSVLR AIPVEVLANS YDISTKEAFR LKNGRQEVEV
560
FLPFQSRDEK ERERF
Length:565
Mass (Da):64,518
Last modified:January 1, 1998 - v1
Checksum:i2DD7FCC64E3CD4F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87980 mRNA. Translation: BAA21758.1.
PIRiT10696.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87980 mRNA. Translation: BAA21758.1.
PIRiT10696.

3D structure databases

ProteinModelPortaliO23878.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei698. Fag e 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.120.10. 3 hits.
InterProiIPR006044. 11S_seedstore_pln.
IPR006045. Cupin_1.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF00190. Cupin_1. 2 hits.
[Graphical view]
PRINTSiPR00439. 11SGLOBULIN.
SMARTiSM00835. Cupin_1. 2 hits.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 3 hits.
ProtoNetiSearch...

Publicationsi

  1. "Expression, cloning, and immunological analysis of buckwheat (Fagopyrum esculentum Moench) seed storage proteins."
    Fujino K., Funatsuki H., Inada M., Shimono Y., Kikuta Y.
    J. Agric. Food Chem. 49:1825-1829(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Strain: cv. Kitayuki.
    Tissue: Immature seed.

Entry informationi

Entry namei13S1_FAGES
AccessioniPrimary (citable) accession number: O23878
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: January 1, 1998
Last modified: May 27, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

The sequence of the probable beta chain is highly homologous to the N-terminal sequence of BW24KD, a major buckwheat allergen.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.