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Protein

Ras-related protein RABC1

Gene

RABC1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Intracellular vesicle trafficking and protein transport.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi20 – 27GTPBy similarity8
Nucleotide bindingi67 – 71GTPBy similarity5
Nucleotide bindingi127 – 130GTPBy similarity4
Nucleotide bindingi157 – 158GTPBy similarity2

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-6798695. Neutrophil degranulation.
R-ATH-6811436. COPI-independent Golgi-to-ER retrograde traffic.
R-ATH-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABC1
Short name:
AtRABC1
Alternative name(s):
Ras-related protein Rab18
Short name:
AtRab18
Gene namesi
Name:RABC1
Synonyms:RAB18, RAB18-1
Ordered Locus Names:At1g43890
ORF Names:F28H19.15, F9C16.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G43890.

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: GOC
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00004073572 – 212Ras-related protein RABC1Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylglycineCombined sources1
Lipidationi209S-geranylgeranyl cysteineBy similarity1
Lipidationi210S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Acetylation, Lipoprotein, Prenylation

Proteomic databases

PaxDbiO23657.
PRIDEiO23657.

Expressioni

Gene expression databases

GenevisibleiO23657. AT.

Interactioni

Protein-protein interaction databases

BioGridi26212. 1 interactor.
IntActiO23657. 1 interactor.
STRINGi3702.AT1G43890.1.

Structurei

3D structure databases

ProteinModelPortaliO23657.
SMRiO23657.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi41 – 49Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0080. Eukaryota.
ENOG410XPD0. LUCA.
HOGENOMiHOG000233968.
InParanoidiO23657.
KOiK07910.
OMAiRKIMETD.
OrthoDBiEOG09360LW8.
PhylomeDBiO23657.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O23657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSSSGQPEF DYLFKVLLIG DSGVGKSSLL LSFTSNTFDD LSPTIGVDFK
60 70 80 90 100
VKYLTIGEKK LKLAIWDTAG QERFRTLTSS YYRGAQGIIM VYDVTRRDTF
110 120 130 140 150
TNLSDIWAKE IDLYSTNQDC IKMLVGNKVD KESERAVSKK EGIDFAREYG
160 170 180 190 200
CLFLECSAKT RVNVEQCFEE LVLKILETPS LTAEGSSGGK KNIFKQNPAQ
210
TTSTSSSYCC SS
Length:212
Mass (Da):23,531
Last modified:January 1, 1998 - v1
Checksum:i042AFFE8C133612C
GO

Sequence cautioni

The sequence AAF79660 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75603 mRNA. Translation: AAB61997.1.
AC006423 Genomic DNA. Translation: AAF63103.1.
AC022314 Genomic DNA. Translation: AAF79660.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32003.1.
CP002684 Genomic DNA. Translation: AEE32004.1.
CP002684 Genomic DNA. Translation: AEE32005.1.
AF370263 mRNA. Translation: AAK44078.1.
AY063080 mRNA. Translation: AAL34254.1.
AK227664 mRNA. Translation: BAE99651.1.
AY086878 mRNA. Translation: AAM63924.1.
PIRiA96503.
RefSeqiNP_001077675.1. NM_001084206.1.
NP_001117435.1. NM_001123963.1.
NP_175056.1. NM_103516.4.
UniGeneiAt.24663.

Genome annotation databases

EnsemblPlantsiAT1G43890.1; AT1G43890.1; AT1G43890.
AT1G43890.2; AT1G43890.2; AT1G43890.
AT1G43890.3; AT1G43890.3; AT1G43890.
GeneIDi840987.
GrameneiAT1G43890.1; AT1G43890.1; AT1G43890.
AT1G43890.2; AT1G43890.2; AT1G43890.
AT1G43890.3; AT1G43890.3; AT1G43890.
KEGGiath:AT1G43890.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75603 mRNA. Translation: AAB61997.1.
AC006423 Genomic DNA. Translation: AAF63103.1.
AC022314 Genomic DNA. Translation: AAF79660.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32003.1.
CP002684 Genomic DNA. Translation: AEE32004.1.
CP002684 Genomic DNA. Translation: AEE32005.1.
AF370263 mRNA. Translation: AAK44078.1.
AY063080 mRNA. Translation: AAL34254.1.
AK227664 mRNA. Translation: BAE99651.1.
AY086878 mRNA. Translation: AAM63924.1.
PIRiA96503.
RefSeqiNP_001077675.1. NM_001084206.1.
NP_001117435.1. NM_001123963.1.
NP_175056.1. NM_103516.4.
UniGeneiAt.24663.

3D structure databases

ProteinModelPortaliO23657.
SMRiO23657.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi26212. 1 interactor.
IntActiO23657. 1 interactor.
STRINGi3702.AT1G43890.1.

Proteomic databases

PaxDbiO23657.
PRIDEiO23657.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G43890.1; AT1G43890.1; AT1G43890.
AT1G43890.2; AT1G43890.2; AT1G43890.
AT1G43890.3; AT1G43890.3; AT1G43890.
GeneIDi840987.
GrameneiAT1G43890.1; AT1G43890.1; AT1G43890.
AT1G43890.2; AT1G43890.2; AT1G43890.
AT1G43890.3; AT1G43890.3; AT1G43890.
KEGGiath:AT1G43890.

Organism-specific databases

TAIRiAT1G43890.

Phylogenomic databases

eggNOGiKOG0080. Eukaryota.
ENOG410XPD0. LUCA.
HOGENOMiHOG000233968.
InParanoidiO23657.
KOiK07910.
OMAiRKIMETD.
OrthoDBiEOG09360LW8.
PhylomeDBiO23657.

Enzyme and pathway databases

ReactomeiR-ATH-6798695. Neutrophil degranulation.
R-ATH-6811436. COPI-independent Golgi-to-ER retrograde traffic.
R-ATH-8876198. RAB GEFs exchange GTP for GDP on RABs.

Miscellaneous databases

PROiO23657.

Gene expression databases

GenevisibleiO23657. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRABC1_ARATH
AccessioniPrimary (citable) accession number: O23657
Secondary accession number(s): Q9LP15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.