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O23657 (RABC1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ras-related protein RABC1

Short name=AtRABC1
Alternative name(s):
Ras-related protein Rab18
Short name=AtRab18
Gene names
Name:RABC1
Synonyms:RAB18, RAB18-1
Ordered Locus Names:At1g43890
ORF Names:F28H19.15, F9C16.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Intracellular vesicle trafficking and protein transport By similarity.

Subcellular location

Cell membrane; Lipid-anchor; Cytoplasmic side Potential.

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Sequence caution

The sequence AAF79660.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.8
Chain2 – 212211Ras-related protein RABC1
PRO_0000407357

Regions

Nucleotide binding20 – 278GTP By similarity
Nucleotide binding67 – 715GTP By similarity
Nucleotide binding127 – 1304GTP By similarity
Nucleotide binding157 – 1582GTP By similarity
Motif41 – 499Effector region By similarity

Amino acid modifications

Modified residue21N-acetylglycine Ref.8
Lipidation2091S-geranylgeranyl cysteine By similarity
Lipidation2101S-geranylgeranyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
O23657 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 042AFFE8C133612C

FASTA21223,531
        10         20         30         40         50         60 
MGSSSGQPEF DYLFKVLLIG DSGVGKSSLL LSFTSNTFDD LSPTIGVDFK VKYLTIGEKK 

        70         80         90        100        110        120 
LKLAIWDTAG QERFRTLTSS YYRGAQGIIM VYDVTRRDTF TNLSDIWAKE IDLYSTNQDC 

       130        140        150        160        170        180 
IKMLVGNKVD KESERAVSKK EGIDFAREYG CLFLECSAKT RVNVEQCFEE LVLKILETPS 

       190        200        210 
LTAEGSSGGK KNIFKQNPAQ TTSTSSSYCC SS 

« Hide

References

« Hide 'large scale' references
[1]"A member of the Rab18-family from Arabidopsis thaliana."
Bischoff F., Palme K.
Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[7]"Analysis of the small GTPase gene superfamily of Arabidopsis."
Vernoud V., Horton A.C., Yang Z., Nielsen E.
Plant Physiol. 131:1191-1208(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[8]"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT GLY-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U75603 mRNA. Translation: AAB61997.1.
AC006423 Genomic DNA. Translation: AAF63103.1.
AC022314 Genomic DNA. Translation: AAF79660.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32003.1.
CP002684 Genomic DNA. Translation: AEE32004.1.
CP002684 Genomic DNA. Translation: AEE32005.1.
AF370263 mRNA. Translation: AAK44078.1.
AY063080 mRNA. Translation: AAL34254.1.
AK227664 mRNA. Translation: BAE99651.1.
AY086878 mRNA. Translation: AAM63924.1.
PIRA96503.
RefSeqNP_001077675.1. NM_001084206.1.
NP_001117435.1. NM_001123963.1.
NP_175056.1. NM_103516.3.
UniGeneAt.24663.

3D structure databases

ProteinModelPortalO23657.
SMRO23657. Positions 14-181.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO23657. 1 interaction.
STRING3702.AT1G43890.2-P.

Proteomic databases

PaxDbO23657.
PRIDEO23657.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G43890.1; AT1G43890.1; AT1G43890.
AT1G43890.2; AT1G43890.2; AT1G43890.
AT1G43890.3; AT1G43890.3; AT1G43890.
GeneID840987.
KEGGath:AT1G43890.

Organism-specific databases

TAIRAT1G43890.

Phylogenomic databases

eggNOGCOG1100.
HOGENOMHOG000233968.
InParanoidO23657.
KOK07910.
OMATYTTRND.
PhylomeDBO23657.
ProtClustDBCLSN2679595.

Gene expression databases

GenevestigatorO23657.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SMARTSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROO23657.

Entry information

Entry nameRABC1_ARATH
AccessionPrimary (citable) accession number: O23657
Secondary accession number(s): Q9LP15
Entry history
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names