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Protein

Ras-related protein RABC1

Gene

RABC1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Intracellular vesicle trafficking and protein transport.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi20 – 27GTPBy similarity8
Nucleotide bindingi67 – 71GTPBy similarity5
Nucleotide bindingi127 – 130GTPBy similarity4
Nucleotide bindingi157 – 158GTPBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-6798695 Neutrophil degranulation
R-ATH-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-ATH-8873719 RAB geranylgeranylation
R-ATH-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABC1
Short name:
AtRABC1
Alternative name(s):
Ras-related protein Rab18
Short name:
AtRab18
Gene namesi
Name:RABC1
Synonyms:RAB18, RAB18-1
Ordered Locus Names:At1g43890
ORF Names:F28H19.15, F9C16.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G43890
TAIRilocus:2029167 AT1G43890

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00004073572 – 212Ras-related protein RABC1Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylglycineCombined sources1
Lipidationi209S-geranylgeranyl cysteineBy similarity1
Lipidationi210S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Acetylation, Lipoprotein, Prenylation

Proteomic databases

PaxDbiO23657
PRIDEiO23657

PTM databases

iPTMnetiO23657

Expressioni

Gene expression databases

ExpressionAtlasiO23657 baseline and differential
GenevisibleiO23657 AT

Interactioni

Protein-protein interaction databases

BioGridi26212, 1 interactor
IntActiO23657, 1 interactor
MINTiO23657
STRINGi3702.AT1G43890.1

Structurei

3D structure databases

ProteinModelPortaliO23657
SMRiO23657
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi41 – 49Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0080 Eukaryota
ENOG410XPD0 LUCA
HOGENOMiHOG000233968
InParanoidiO23657
KOiK07910
OMAiYHISTIG
OrthoDBiEOG09360LW8
PhylomeDBiO23657

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O23657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSSSGQPEF DYLFKVLLIG DSGVGKSSLL LSFTSNTFDD LSPTIGVDFK
60 70 80 90 100
VKYLTIGEKK LKLAIWDTAG QERFRTLTSS YYRGAQGIIM VYDVTRRDTF
110 120 130 140 150
TNLSDIWAKE IDLYSTNQDC IKMLVGNKVD KESERAVSKK EGIDFAREYG
160 170 180 190 200
CLFLECSAKT RVNVEQCFEE LVLKILETPS LTAEGSSGGK KNIFKQNPAQ
210
TTSTSSSYCC SS
Length:212
Mass (Da):23,531
Last modified:January 1, 1998 - v1
Checksum:i042AFFE8C133612C
GO

Sequence cautioni

The sequence AAF79660 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75603 mRNA Translation: AAB61997.1
AC006423 Genomic DNA Translation: AAF63103.1
AC022314 Genomic DNA Translation: AAF79660.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE32003.1
CP002684 Genomic DNA Translation: AEE32004.1
CP002684 Genomic DNA Translation: AEE32005.1
AF370263 mRNA Translation: AAK44078.1
AY063080 mRNA Translation: AAL34254.1
AK227664 mRNA Translation: BAE99651.1
AY086878 mRNA Translation: AAM63924.1
PIRiA96503
RefSeqiNP_001077675.1, NM_001084206.1
NP_001117435.1, NM_001123963.1
NP_175056.1, NM_103516.4
UniGeneiAt.24663

Genome annotation databases

EnsemblPlantsiAT1G43890.1; AT1G43890.1; AT1G43890
AT1G43890.2; AT1G43890.2; AT1G43890
AT1G43890.3; AT1G43890.3; AT1G43890
GeneIDi840987
GrameneiAT1G43890.1; AT1G43890.1; AT1G43890
AT1G43890.2; AT1G43890.2; AT1G43890
AT1G43890.3; AT1G43890.3; AT1G43890
KEGGiath:AT1G43890

Similar proteinsi

Entry informationi

Entry nameiRABC1_ARATH
AccessioniPrimary (citable) accession number: O23657
Secondary accession number(s): Q9LP15
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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