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Protein

Monothiol glutaredoxin-S3

Gene

GRXS3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May only reduce GSH-thiol disulfides, but not protein disulfides.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi21 – 211Iron-sulfur (2Fe-2S); shared with dimeric partnerSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Monothiol glutaredoxin-S3
Short name:
AtGrxS3
Alternative name(s):
Protein ROXY 11
Gene namesi
Name:GRXS3
Synonyms:ROXY11
Ordered Locus Names:At4g15700
ORF Names:dl3890w, FCAALL.358
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G15700.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 102102Monothiol glutaredoxin-S3PRO_0000268724Add
BLAST

Proteomic databases

PaxDbiO23421.

Expressioni

Gene expression databases

GenevisibleiO23421. AT.

Interactioni

Protein-protein interaction databases

BioGridi12541. 11 interactions.
IntActiO23421. 10 interactions.
STRINGi3702.AT4G15700.1.

Structurei

3D structure databases

ProteinModelPortaliO23421.
SMRiO23421. Positions 4-99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 101101GlutaredoxinPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi99 – 1024Responsive for interaction with TGA factorsBy similarity

Sequence similaritiesi

Belongs to the glutaredoxin family. CC-type subfamily.Curated
Contains 1 glutaredoxin domain.PROSITE-ProRule annotation

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
COG0695. LUCA.
HOGENOMiHOG000095204.
InParanoidiO23421.
OMAiASSCCMC.
OrthoDBiEOG09360V1H.
PhylomeDBiO23421.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011905. GlrX-like_pln_2.
IPR002109. Glutaredoxin.
IPR014025. Glutaredoxin_subgr.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSiPR00160. GLUTAREDOXIN.
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02189. GlrX-like_plant. 1 hit.
PROSITEiPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O23421-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENLQKMISE KSVVIFSKNS CCMSHTIKTL FLDLGVNPTI YELDEISRGK
60 70 80 90 100
EIEHALAQLG CSPTVPVVFI GGQLVGGANQ VMSLHLNRSL VPMLKRAGAL

WL
Length:102
Mass (Da):11,168
Last modified:January 1, 1998 - v1
Checksum:i50C4FCD50BE39114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611911 mRNA. Translation: ACO50416.1.
Z97339 Genomic DNA. Translation: CAB10348.1.
AL161542 Genomic DNA. Translation: CAB78612.1.
CP002687 Genomic DNA. Translation: AEE83637.1.
BT010804 mRNA. Translation: AAR24171.1.
BT011292 mRNA. Translation: AAR92328.1.
PIRiB71422.
RefSeqiNP_193305.1. NM_117661.3.
UniGeneiAt.43586.

Genome annotation databases

EnsemblPlantsiAT4G15700.1; AT4G15700.1; AT4G15700.
GeneIDi827247.
GrameneiAT4G15700.1; AT4G15700.1; AT4G15700.
KEGGiath:AT4G15700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611911 mRNA. Translation: ACO50416.1.
Z97339 Genomic DNA. Translation: CAB10348.1.
AL161542 Genomic DNA. Translation: CAB78612.1.
CP002687 Genomic DNA. Translation: AEE83637.1.
BT010804 mRNA. Translation: AAR24171.1.
BT011292 mRNA. Translation: AAR92328.1.
PIRiB71422.
RefSeqiNP_193305.1. NM_117661.3.
UniGeneiAt.43586.

3D structure databases

ProteinModelPortaliO23421.
SMRiO23421. Positions 4-99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi12541. 11 interactions.
IntActiO23421. 10 interactions.
STRINGi3702.AT4G15700.1.

Proteomic databases

PaxDbiO23421.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G15700.1; AT4G15700.1; AT4G15700.
GeneIDi827247.
GrameneiAT4G15700.1; AT4G15700.1; AT4G15700.
KEGGiath:AT4G15700.

Organism-specific databases

TAIRiAT4G15700.

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
COG0695. LUCA.
HOGENOMiHOG000095204.
InParanoidiO23421.
OMAiASSCCMC.
OrthoDBiEOG09360V1H.
PhylomeDBiO23421.

Miscellaneous databases

PROiO23421.

Gene expression databases

GenevisibleiO23421. AT.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011905. GlrX-like_pln_2.
IPR002109. Glutaredoxin.
IPR014025. Glutaredoxin_subgr.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSiPR00160. GLUTAREDOXIN.
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02189. GlrX-like_plant. 1 hit.
PROSITEiPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGRXS3_ARATH
AccessioniPrimary (citable) accession number: O23421
Secondary accession number(s): C1JGQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.