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Protein

Monothiol glutaredoxin-S3

Gene

GRXS3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May only reduce GSH-thiol disulfides, but not protein disulfides.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi21Iron-sulfur (2Fe-2S); shared with dimeric partnerSequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Ligand2Fe-2S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Monothiol glutaredoxin-S3
Short name:
AtGrxS3
Alternative name(s):
Protein ROXY 11
Gene namesi
Name:GRXS3
Synonyms:ROXY11
Ordered Locus Names:At4g15700
ORF Names:dl3890w, FCAALL.358
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G15700
TAIRilocus:2130574 AT4G15700

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002687241 – 102Monothiol glutaredoxin-S3Add BLAST102

Proteomic databases

PaxDbiO23421

Expressioni

Gene expression databases

ExpressionAtlasiO23421 baseline and differential
GenevisibleiO23421 AT

Interactioni

Protein-protein interaction databases

BioGridi12541, 11 interactors
IntActiO23421, 10 interactors
STRINGi3702.AT4G15700.1

Structurei

3D structure databases

ProteinModelPortaliO23421
SMRiO23421
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 101GlutaredoxinPROSITE-ProRule annotationAdd BLAST101

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi99 – 102Responsive for interaction with TGA factorsBy similarity4

Sequence similaritiesi

Belongs to the glutaredoxin family. CC-type subfamily.Curated

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiKOG1752 Eukaryota
COG0695 LUCA
HOGENOMiHOG000095204
InParanoidiO23421
OMAiSKSSCCI
OrthoDBiEOG09360V1H
PhylomeDBiO23421

Family and domain databases

InterProiView protein in InterPro
IPR011905 GlrX-like_pln_2
IPR002109 Glutaredoxin
IPR014025 Glutaredoxin_subgr
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00462 Glutaredoxin, 1 hit
PRINTSiPR00160 GLUTAREDOXIN
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR02189 GlrX-like_plant, 1 hit
PROSITEiView protein in PROSITE
PS51354 GLUTAREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

O23421-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENLQKMISE KSVVIFSKNS CCMSHTIKTL FLDLGVNPTI YELDEISRGK
60 70 80 90 100
EIEHALAQLG CSPTVPVVFI GGQLVGGANQ VMSLHLNRSL VPMLKRAGAL

WL
Length:102
Mass (Da):11,168
Last modified:January 1, 1998 - v1
Checksum:i50C4FCD50BE39114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611911 mRNA Translation: ACO50416.1
Z97339 Genomic DNA Translation: CAB10348.1
AL161542 Genomic DNA Translation: CAB78612.1
CP002687 Genomic DNA Translation: AEE83637.1
BT010804 mRNA Translation: AAR24171.1
BT011292 mRNA Translation: AAR92328.1
PIRiB71422
RefSeqiNP_193305.1, NM_117661.4
UniGeneiAt.43586

Genome annotation databases

EnsemblPlantsiAT4G15700.1; AT4G15700.1; AT4G15700
GeneIDi827247
GrameneiAT4G15700.1; AT4G15700.1; AT4G15700
KEGGiath:AT4G15700

Similar proteinsi

Entry informationi

Entry nameiGRXS3_ARATH
AccessioniPrimary (citable) accession number: O23421
Secondary accession number(s): C1JGQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health