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Protein

Monothiol glutaredoxin-S5

Gene

GRXS5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May only reduce GSH-thiol disulfides, but not protein disulfides.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi21Iron-sulfur (2Fe-2S); shared with dimeric partnerSequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Ligand2Fe-2S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Monothiol glutaredoxin-S5
Short name:
AtGrxS5
Alternative name(s):
Protein ROXY 12
Gene namesi
Name:GRXS5
Synonyms:ROXY12
Ordered Locus Names:At4g15690
ORF Names:dl3885w, FCAALL.357
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G15690
TAIRilocus:2130569 AT4G15690

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002687261 – 102Monothiol glutaredoxin-S5Add BLAST102

Proteomic databases

PaxDbiO23420

Expressioni

Gene expression databases

ExpressionAtlasiO23420 baseline and differential
GenevisibleiO23420 AT

Interactioni

Protein-protein interaction databases

BioGridi12540, 1 interactor
STRINGi3702.AT4G15690.1

Structurei

3D structure databases

ProteinModelPortaliO23420
SMRiO23420
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 101GlutaredoxinPROSITE-ProRule annotationAdd BLAST101

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi99 – 102Responsive for interaction with TGA factorsBy similarity4

Sequence similaritiesi

Belongs to the glutaredoxin family. CC-type subfamily.Curated

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiKOG1752 Eukaryota
COG0695 LUCA
HOGENOMiHOG000095204
InParanoidiO23420
OMAiNPTICEL
OrthoDBiEOG09360V1H
PhylomeDBiO23420

Family and domain databases

InterProiView protein in InterPro
IPR011905 GlrX-like_pln_2
IPR002109 Glutaredoxin
IPR014025 Glutaredoxin_subgr
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00462 Glutaredoxin, 1 hit
PRINTSiPR00160 GLUTAREDOXIN
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR02189 GlrX-like_plant, 1 hit
PROSITEiView protein in PROSITE
PS51354 GLUTAREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

O23420-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENLQKMISE KSVVIFSKNS CCMSHTIKTL FLDFGVNPTI YELDEINIGR
60 70 80 90 100
EIEQALAQLG CSPTVPVVFI GGQLVGGANQ VMSLHLNRSL VPMLKRAGAL

WL
Length:102
Mass (Da):11,205
Last modified:January 1, 1998 - v1
Checksum:i8DE04C00E690D7D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611912 mRNA Translation: ACO50417.1
Z97339 Genomic DNA Translation: CAB10347.1
AL161542 Genomic DNA Translation: CAB78611.1
CP002687 Genomic DNA Translation: AEE83636.1
BT010811 mRNA Translation: AAR24178.1
BT011293 mRNA Translation: AAR92329.1
PIRiA71422
RefSeqiNP_193304.1, NM_117660.3
UniGeneiAt.33152

Genome annotation databases

EnsemblPlantsiAT4G15690.1; AT4G15690.1; AT4G15690
GeneIDi827246
GrameneiAT4G15690.1; AT4G15690.1; AT4G15690
KEGGiath:AT4G15690

Similar proteinsi

Entry informationi

Entry nameiGRXS5_ARATH
AccessioniPrimary (citable) accession number: O23420
Secondary accession number(s): C1JGQ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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