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Protein

Monothiol glutaredoxin-S4

Gene

GRXS4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May only reduce GSH-thiol disulfides, but not protein disulfides.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi21Iron-sulfur (2Fe-2S); shared with dimeric partnerSequence analysis1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Monothiol glutaredoxin-S4
Short name:
AtGrxS4
Alternative name(s):
Protein ROXY 13
Gene namesi
Name:GRXS4
Synonyms:ROXY13
Ordered Locus Names:At4g15680
ORF Names:dl3880w, FCAALL.384
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G15680.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002687251 – 102Monothiol glutaredoxin-S4Add BLAST102

Proteomic databases

PaxDbiO23419.
PRIDEiO23419.

Expressioni

Gene expression databases

GenevisibleiO23419. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G15680.1.

Structurei

3D structure databases

ProteinModelPortaliO23419.
SMRiO23419.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 101GlutaredoxinPROSITE-ProRule annotationAdd BLAST101

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi99 – 102Responsive for interaction with TGA factorsBy similarity4

Sequence similaritiesi

Belongs to the glutaredoxin family. CC-type subfamily.Curated
Contains 1 glutaredoxin domain.PROSITE-ProRule annotation

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
COG0695. LUCA.
HOGENOMiHOG000095204.
InParanoidiO23419.
OMAiCHTVTTL.
OrthoDBiEOG09360V1H.
PhylomeDBiO23419.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011905. GlrX-like_pln_2.
IPR002109. Glutaredoxin.
IPR014025. Glutaredoxin_subgr.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSiPR00160. GLUTAREDOXIN.
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02189. GlrX-like_plant. 1 hit.
PROSITEiPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O23419-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLQKMISE KSVVIFSKNS CCMSHTIKTL FIDFGVNPTI YELDEINRGK
60 70 80 90 100
EIEQALAQLG CSPTVPVVFI GGQLVGGANQ VMSLHLNRSL VPMLKRVGAL

WL
Length:102
Mass (Da):11,248
Last modified:January 1, 1998 - v1
Checksum:i05FB1343F4CFD0A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611913 mRNA. Translation: ACO50418.1.
Z97339 Genomic DNA. Translation: CAB10346.1.
AL161542 Genomic DNA. Translation: CAB78610.1.
CP002687 Genomic DNA. Translation: AEE83635.1.
BT024665 mRNA. Translation: ABD57490.1.
AY087144 mRNA. Translation: AAM64702.1.
PIRiH71421.
RefSeqiNP_193303.1. NM_117659.2.
UniGeneiAt.33153.

Genome annotation databases

EnsemblPlantsiAT4G15680.1; AT4G15680.1; AT4G15680.
GeneIDi827245.
GrameneiAT4G15680.1; AT4G15680.1; AT4G15680.
KEGGiath:AT4G15680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ611913 mRNA. Translation: ACO50418.1.
Z97339 Genomic DNA. Translation: CAB10346.1.
AL161542 Genomic DNA. Translation: CAB78610.1.
CP002687 Genomic DNA. Translation: AEE83635.1.
BT024665 mRNA. Translation: ABD57490.1.
AY087144 mRNA. Translation: AAM64702.1.
PIRiH71421.
RefSeqiNP_193303.1. NM_117659.2.
UniGeneiAt.33153.

3D structure databases

ProteinModelPortaliO23419.
SMRiO23419.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G15680.1.

Proteomic databases

PaxDbiO23419.
PRIDEiO23419.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G15680.1; AT4G15680.1; AT4G15680.
GeneIDi827245.
GrameneiAT4G15680.1; AT4G15680.1; AT4G15680.
KEGGiath:AT4G15680.

Organism-specific databases

TAIRiAT4G15680.

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
COG0695. LUCA.
HOGENOMiHOG000095204.
InParanoidiO23419.
OMAiCHTVTTL.
OrthoDBiEOG09360V1H.
PhylomeDBiO23419.

Miscellaneous databases

PROiO23419.

Gene expression databases

GenevisibleiO23419. AT.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011905. GlrX-like_pln_2.
IPR002109. Glutaredoxin.
IPR014025. Glutaredoxin_subgr.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSiPR00160. GLUTAREDOXIN.
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02189. GlrX-like_plant. 1 hit.
PROSITEiPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGRXS4_ARATH
AccessioniPrimary (citable) accession number: O23419
Secondary accession number(s): C1JGQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.