Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Baruol synthase

Gene

BARS1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Converts oxidosqualene to baruol (90%) and 22 minor products.1 Publication

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = baruol.1 Publication

GO - Molecular functioni

  • baruol synthase activity Source: TAIR

GO - Biological processi

  • tetracyclic triterpenoid biosynthetic process Source: TAIR

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyciMetaCyc:AT4G15370-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Baruol synthase (EC:5.4.99.57)
Short name:
AtBARS1
Alternative name(s):
Pentacyclic triterpene synthase 2
Short name:
AtPEN2
Gene namesi
Name:BARS1
Synonyms:PEN2
Ordered Locus Names:At4g15370
ORF Names:dl3730c, FCAALL.279
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G15370
TAIRilocus:2130040 AT4G15370

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003661371 – 759Baruol synthaseAdd BLAST759

Proteomic databases

PaxDbiO23390

Expressioni

Gene expression databases

ExpressionAtlasiO23390 baseline and differential
GenevisibleiO23390 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G15370.1

Structurei

3D structure databases

ProteinModelPortaliO23390
SMRiO23390
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati149 – 190PFTB 1Add BLAST42
Repeati522 – 564PFTB 2Add BLAST43
Repeati641 – 682PFTB 3Add BLAST42

Sequence similaritiesi

Belongs to the terpene cyclase/mutase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0497 Eukaryota
COG1657 LUCA
HOGENOMiHOG000234317
InParanoidiO23390
KOiK16206
OMAiIFTHEHR
OrthoDBiEOG093611Z0
PhylomeDBiO23390

Family and domain databases

CDDicd02892 SQCY_1, 1 hit
InterProiView protein in InterPro
IPR032696 SQ_cyclase_C
IPR032697 SQ_cyclase_N
IPR018333 Squalene_cyclase
IPR002365 Terpene_synthase_CS
IPR008930 Terpenoid_cyclase/PrenylTrfase
PfamiView protein in Pfam
PF13243 SQHop_cyclase_C, 1 hit
PF13249 SQHop_cyclase_N, 1 hit
SUPFAMiSSF48239 SSF48239, 2 hits
TIGRFAMsiTIGR01787 squalene_cyclas, 1 hit
PROSITEiView protein in PROSITE
PS01074 TERPENE_SYNTHASES, 1 hit

Sequencei

Sequence statusi: Complete.

O23390-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRLRIGAKA KDNTHLFTTN NYVGRQIWEF DANAGSPEEL AEVEEARRNF
60 70 80 90 100
SNNRSRFKAS ADLLWRMQFL REKKFEQKIP RVIVEDAEKI TYEDAKTALR
110 120 130 140 150
RGLLYFTALQ ADDGHWPAEN AGSIFFNAPF VICLYITGHL EKIFTHEHRV
160 170 180 190 200
ELLRYMYNHQ NEDGGWGLHV ESPSNMFCSV INYICLRILG VEAGHDDKGS
210 220 230 240 250
ACARARKWIL DHGGATYSPL IGKAWLSVLG VYDWSGCKPI PPEFWFLPSF
260 270 280 290 300
FPVNGGTLWI YLRDIFMGLS YLYGKNFVAT STPLILQLRE EIYPEPYTNI
310 320 330 340 350
SWRQARNRCA KEDLYYPQSF LQDLFWKGVH VFSENILNRW PFNNLIRQRA
360 370 380 390 400
LRTTMELVHY HDEATRYITG GSVPKVIAVF HMLACWVEDP ESDYFKKHLA
410 420 430 440 450
RVPDFIWIGE DGLKIQSFGS QVWDTALSLH VFIDGFDDDV DEEIRSTLLK
460 470 480 490 500
GYDYLEKSQV TENPPGDYMK MFRHMAKGGW TFSDQDQGWP VSDCTAESLE
510 520 530 540 550
CCLFFESMSS EFIGKKMDVE KLYDAVDFLL YLQSDNGGIT AWQPADGKLV
560 570 580 590 600
EFIEDAVVEH EYVECTGSAI VALAQFNKQF PGYKKEEVER FITKGVKYIE
610 620 630 640 650
DLQMVDGSWY GNWGVCFIYG TFFAVRGLVA AGKCYNNCEA IRRAVRFILD
660 670 680 690 700
TQNTEGGWGE SYLSCPRKKY IPLIGNKTNV VNTGQALMVL IMGNQMKRDP
710 720 730 740 750
LPVHRAAKVL INSQMDNGDF PQQEIMGVFK MNVMLHFPTY RNMFTLWALT

HYTKALRGL
Length:759
Mass (Da):87,455
Last modified:March 3, 2009 - v2
Checksum:i620E96D9085213C1
GO

Sequence cautioni

The sequence CAB10316 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB78579 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97338 Genomic DNA Translation: CAB10316.1 Sequence problems.
AL161541 Genomic DNA Translation: CAB78579.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83589.1
PIRiB71418
RefSeqiNP_193272.1, NM_117625.2

Genome annotation databases

EnsemblPlantsiAT4G15370.1; AT4G15370.1; AT4G15370
GeneIDi827203
GrameneiAT4G15370.1; AT4G15370.1; AT4G15370
KEGGiath:AT4G15370

Similar proteinsi

Entry informationi

Entry nameiBARS1_ARATH
AccessioniPrimary (citable) accession number: O23390
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome