Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Calmodulin-like protein 8

Gene

CML8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Potential calcium sensor.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi22 – 33121PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi58 – 69122PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi95 – 106123PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi131 – 142124PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • calcium-mediated signaling Source: TAIR
  • detection of calcium ion Source: TAIR
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-like protein 8
Short name:
AtCaM-8
Gene namesi
Name:CML8
Synonyms:CAM8
Ordered Locus Names:At4g14640
ORF Names:dl3360w, FCAALL.157
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G14640.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Calmodulin-like protein 8PRO_0000073652Add
BLAST

Proteomic databases

PaxDbiO23320.

Expressioni

Tissue specificityi

Expressed at low levels in leaves, flowers and siliques.1 Publication

Gene expression databases

GenevisibleiO23320. AT.

Interactioni

Subunit structurei

Interacts with ZAR1 (via CaMBD domain).1 Publication

Protein-protein interaction databases

BioGridi12411. 4 interactions.
IntActiO23320. 77 interactions.
STRINGi3702.AT4G14640.1.

Structurei

3D structure databases

ProteinModelPortaliO23320.
SMRiO23320. Positions 6-150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 4436EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini45 – 8036EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini82 – 11736EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini118 – 15134EF-hand 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the calmodulin family.Curated
Contains 4 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0027. Eukaryota.
COG5126. LUCA.
HOGENOMiHOG000233018.
InParanoidiO23320.
KOiK13448.
OMAiMVEFKEA.
OrthoDBiEOG09360QIJ.
PhylomeDBiO23320.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O23320-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEETALTKDQ ITEFKEAFCL FDKDGDGCIT VEELATVIRS LDQNPTEQEL
60 70 80 90 100
HDIITEIDSD SNGTIEFAEF LNLMAKKLQE SDAEEELKEA FKVFDKDQNG
110 120 130 140 150
YISASELSHV MINLGEKLTD EEVEQMIKEA DLDGDGQVNY DEFVKMMINI

D
Length:151
Mass (Da):17,156
Last modified:January 1, 1998 - v1
Checksum:iA72571DC7EAB2427
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF178074 mRNA. Translation: AAD53314.1.
Z97336 Genomic DNA. Translation: CAB10243.1.
AL161539 Genomic DNA. Translation: CAB78506.1.
CP002687 Genomic DNA. Translation: AEE83470.1.
BT024688 mRNA. Translation: ABD57513.1.
PIRiA71409.
RefSeqiNP_193200.1. NM_117546.3.
UniGeneiAt.4288.

Genome annotation databases

EnsemblPlantsiAT4G14640.1; AT4G14640.1; AT4G14640.
GeneIDi827114.
GrameneiAT4G14640.1; AT4G14640.1; AT4G14640.
KEGGiath:AT4G14640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF178074 mRNA. Translation: AAD53314.1.
Z97336 Genomic DNA. Translation: CAB10243.1.
AL161539 Genomic DNA. Translation: CAB78506.1.
CP002687 Genomic DNA. Translation: AEE83470.1.
BT024688 mRNA. Translation: ABD57513.1.
PIRiA71409.
RefSeqiNP_193200.1. NM_117546.3.
UniGeneiAt.4288.

3D structure databases

ProteinModelPortaliO23320.
SMRiO23320. Positions 6-150.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi12411. 4 interactions.
IntActiO23320. 77 interactions.
STRINGi3702.AT4G14640.1.

Proteomic databases

PaxDbiO23320.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G14640.1; AT4G14640.1; AT4G14640.
GeneIDi827114.
GrameneiAT4G14640.1; AT4G14640.1; AT4G14640.
KEGGiath:AT4G14640.

Organism-specific databases

TAIRiAT4G14640.

Phylogenomic databases

eggNOGiKOG0027. Eukaryota.
COG5126. LUCA.
HOGENOMiHOG000233018.
InParanoidiO23320.
KOiK13448.
OMAiMVEFKEA.
OrthoDBiEOG09360QIJ.
PhylomeDBiO23320.

Miscellaneous databases

PROiO23320.

Gene expression databases

GenevisibleiO23320. AT.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCML8_ARATH
AccessioniPrimary (citable) accession number: O23320
Secondary accession number(s): Q29Q68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.