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Protein

Calmodulin-like protein 8

Gene

CML8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Potential calcium sensor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi22 – 331PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi58 – 692PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi95 – 1063PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi131 – 1424PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

  • calcium-mediated signaling Source: TAIR
  • detection of calcium ion Source: TAIR

Keywordsi

LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-like protein 8
Short name:
AtCaM-8
Gene namesi
Name:CML8
Synonyms:CAM8
Ordered Locus Names:At4g14640
ORF Names:dl3360w, FCAALL.157
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G14640
TAIRilocus:2130035 AT4G14640

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000736521 – 151Calmodulin-like protein 8Add BLAST151

Proteomic databases

PaxDbiO23320

Expressioni

Tissue specificityi

Expressed at low levels in leaves, flowers and siliques.1 Publication

Gene expression databases

ExpressionAtlasiO23320 baseline and differential
GenevisibleiO23320 AT

Interactioni

Subunit structurei

Interacts with ZAR1 (via CaMBD domain) (PubMed:27014878). Binds to IQD1 (PubMed:23204523).2 Publications

Protein-protein interaction databases

BioGridi12411, 4 interactors
IntActiO23320, 78 interactors
STRINGi3702.AT4G14640.1

Structurei

3D structure databases

ProteinModelPortaliO23320
SMRiO23320
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 44EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini45 – 80EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini82 – 117EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini118 – 151EF-hand 4PROSITE-ProRule annotationAdd BLAST34

Sequence similaritiesi

Belongs to the calmodulin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
HOGENOMiHOG000233018
InParanoidiO23320
KOiK13448
OMAiNATIEFA
OrthoDBiEOG09360QIJ
PhylomeDBiO23320

Family and domain databases

CDDicd00051 EFh, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 4 hits

Sequencei

Sequence statusi: Complete.

O23320-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEETALTKDQ ITEFKEAFCL FDKDGDGCIT VEELATVIRS LDQNPTEQEL
60 70 80 90 100
HDIITEIDSD SNGTIEFAEF LNLMAKKLQE SDAEEELKEA FKVFDKDQNG
110 120 130 140 150
YISASELSHV MINLGEKLTD EEVEQMIKEA DLDGDGQVNY DEFVKMMINI

D
Length:151
Mass (Da):17,156
Last modified:January 1, 1998 - v1
Checksum:iA72571DC7EAB2427
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF178074 mRNA Translation: AAD53314.1
Z97336 Genomic DNA Translation: CAB10243.1
AL161539 Genomic DNA Translation: CAB78506.1
CP002687 Genomic DNA Translation: AEE83470.1
BT024688 mRNA Translation: ABD57513.1
PIRiA71409
RefSeqiNP_193200.1, NM_117546.4
UniGeneiAt.4288

Genome annotation databases

EnsemblPlantsiAT4G14640.1; AT4G14640.1; AT4G14640
GeneIDi827114
GrameneiAT4G14640.1; AT4G14640.1; AT4G14640
KEGGiath:AT4G14640

Similar proteinsi

Entry informationi

Entry nameiCML8_ARATH
AccessioniPrimary (citable) accession number: O23320
Secondary accession number(s): Q29Q68
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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