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Protein

Probable disease resistance protein At4g14610

Gene

At4g14610

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable disease resistance protein.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi156 – 1638ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Plant defense

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable disease resistance protein At4g14610
Alternative name(s):
pCol1
Gene namesi
Ordered Locus Names:At4g14610
ORF Names:dl3345c, FCAALL.272
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G14610.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 719719Probable disease resistance protein At4g14610PRO_0000212756Add
BLAST

Proteomic databases

PRIDEiO23317.

Interactioni

Protein-protein interaction databases

IntActiO23317. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliO23317.
SMRiO23317. Positions 422-455.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini114 – 418305NB-ARCAdd
BLAST
Repeati400 – 42122LRR 1Add
BLAST
Repeati422 – 44423LRR 2Add
BLAST
Repeati447 – 46923LRR 3Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili25 – 7349Sequence analysisAdd
BLAST

Domaini

The LRR repeats probably act as specificity determinant of pathogen recognition.By similarity

Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.Curated
Contains 3 LRR (leucine-rich) repeats.Curated
Contains 1 NB-ARC domain.Curated

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

InParanoidiO23317.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

O23317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTKLRFVN QFSQWLCVRK GYIHSLPENL AALQKAIEVL KTKHDDVKRR
60 70 80 90 100
VDKEEFLGRR HRLSQVQVEI ERLCFCGFCS KSFGKSYHYG KMVSVMLKEV
110 120 130 140 150
ENLSSRGVFD VVTEENLVAQ VEEMPIQSTV VGQETMLERV WNTLMKDGFK
160 170 180 190 200
IMGLYGMGGV GKTTLLTQIN KKFSETDGGF DIVMWVVVSK TSEIYRIQED
210 220 230 240 250
IAKRLGLTGE EWDKKNENKR AVDIHNVLRR HKFVLLLDDI WEKVNLELVG
260 270 280 290 300
VPYPSRENGS IVAFTTRSRD VCGRMGVDDP MQVSCLEPED AWDLFQNKVG
310 320 330 340 350
ENTLKSHPDI PELAKQVAEK CRGLPLALNV IGETMACKST VQEWRHAIDE
360 370 380 390 400
EWKKTEVKMH DVVREMALWI SSDLGKHKDQ CIVRAGVGLH AVPEVKNWRA
410 420 430 440 450
VRRMSLMKNE LEKILGCPTC PQLTTLLLQK NHKLVNISGE FFRFMPNLVV
460 470 480 490 500
LDLSWNSSLT GLPKKISEVE TTNTSEFGVH EEFGEYAGVS KLLSLKTLRL
510 520 530 540 550
QKSKKALDVN SAKELQLLEH IEVLTIDIFS KVEEESFKIL TFPSMCNIRR
560 570 580 590 600
IGIWKCGMKE IKVEMRTSSC FSSLSKVVIG QCDGLKELTW LLFAPNLTYL
610 620 630 640 650
DARFAEQLED IISEEKAASV TDENASIIIP FQKLECLSLS DLPKLKSIYW
660 670 680 690 700
SPLSFPRLSE LAVQEHCPKL KKLPLNSKSG TAGVELVVKY GENKWLEGVE
710
WEDKATELRF LATCKSLYR
Length:719
Mass (Da):81,918
Last modified:January 1, 1998 - v1
Checksum:iA7C353F05992CFCF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti172 – 1721K → R in AAC50029 (PubMed:9670562).Curated
Sequence conflicti239 – 2391D → G in AAC50029 (PubMed:9670562).Curated
Sequence conflicti241 – 2411W → C in AAC50029 (PubMed:9670562).Curated
Sequence conflicti271 – 2711V → G in AAC14554 (PubMed:9530866).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97336 Genomic DNA. Translation: CAB10240.1.
AL161539 Genomic DNA. Translation: CAB78503.1.
CP002687 Genomic DNA. No translation available.
U97222 Genomic DNA. Translation: AAC50029.1.
AF039378 Genomic DNA. Translation: AAC14554.1.
PIRiF71408.

Cross-referencesi

Web resourcesi

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97336 Genomic DNA. Translation: CAB10240.1.
AL161539 Genomic DNA. Translation: CAB78503.1.
CP002687 Genomic DNA. No translation available.
U97222 Genomic DNA. Translation: AAC50029.1.
AF039378 Genomic DNA. Translation: AAC14554.1.
PIRiF71408.

3D structure databases

ProteinModelPortaliO23317.
SMRiO23317. Positions 422-455.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO23317. 1 interaction.

Proteomic databases

PRIDEiO23317.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

TAIRiAT4G14610.

Phylogenomic databases

InParanoidiO23317.

Miscellaneous databases

PROiO23317.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDRL24_ARATH
AccessioniPrimary (citable) accession number: O23317
Secondary accession number(s): O64972, O82101
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: January 1, 1998
Last modified: January 20, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.