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Protein

Probable disease resistance protein At4g14610

Gene

At4g14610

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probable disease resistance protein.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi156 – 163ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processPlant defense
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable disease resistance protein At4g14610
Alternative name(s):
pCol1
Gene namesi
Ordered Locus Names:At4g14610
ORF Names:dl3345c, FCAALL.272
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G14610

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002127561 – 719Probable disease resistance protein At4g14610Add BLAST719

Proteomic databases

PRIDEiO23317

Expressioni

Gene expression databases

ExpressionAtlasiO23317 differential

Interactioni

Protein-protein interaction databases

IntActiO23317, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliO23317
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini114 – 418NB-ARCAdd BLAST305
Repeati400 – 421LRR 1Add BLAST22
Repeati422 – 444LRR 2Add BLAST23
Repeati447 – 469LRR 3Add BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili25 – 73Sequence analysisAdd BLAST49

Domaini

The LRR repeats probably act as specificity determinant of pathogen recognition.By similarity

Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.Curated

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

InParanoidiO23317

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF13855 LRR_8, 1 hit
PF00931 NB-ARC, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

O23317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTKLRFVN QFSQWLCVRK GYIHSLPENL AALQKAIEVL KTKHDDVKRR
60 70 80 90 100
VDKEEFLGRR HRLSQVQVEI ERLCFCGFCS KSFGKSYHYG KMVSVMLKEV
110 120 130 140 150
ENLSSRGVFD VVTEENLVAQ VEEMPIQSTV VGQETMLERV WNTLMKDGFK
160 170 180 190 200
IMGLYGMGGV GKTTLLTQIN KKFSETDGGF DIVMWVVVSK TSEIYRIQED
210 220 230 240 250
IAKRLGLTGE EWDKKNENKR AVDIHNVLRR HKFVLLLDDI WEKVNLELVG
260 270 280 290 300
VPYPSRENGS IVAFTTRSRD VCGRMGVDDP MQVSCLEPED AWDLFQNKVG
310 320 330 340 350
ENTLKSHPDI PELAKQVAEK CRGLPLALNV IGETMACKST VQEWRHAIDE
360 370 380 390 400
EWKKTEVKMH DVVREMALWI SSDLGKHKDQ CIVRAGVGLH AVPEVKNWRA
410 420 430 440 450
VRRMSLMKNE LEKILGCPTC PQLTTLLLQK NHKLVNISGE FFRFMPNLVV
460 470 480 490 500
LDLSWNSSLT GLPKKISEVE TTNTSEFGVH EEFGEYAGVS KLLSLKTLRL
510 520 530 540 550
QKSKKALDVN SAKELQLLEH IEVLTIDIFS KVEEESFKIL TFPSMCNIRR
560 570 580 590 600
IGIWKCGMKE IKVEMRTSSC FSSLSKVVIG QCDGLKELTW LLFAPNLTYL
610 620 630 640 650
DARFAEQLED IISEEKAASV TDENASIIIP FQKLECLSLS DLPKLKSIYW
660 670 680 690 700
SPLSFPRLSE LAVQEHCPKL KKLPLNSKSG TAGVELVVKY GENKWLEGVE
710
WEDKATELRF LATCKSLYR
Length:719
Mass (Da):81,918
Last modified:January 1, 1998 - v1
Checksum:iA7C353F05992CFCF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti172K → R in AAC50029 (PubMed:9670562).Curated1
Sequence conflicti239D → G in AAC50029 (PubMed:9670562).Curated1
Sequence conflicti241W → C in AAC50029 (PubMed:9670562).Curated1
Sequence conflicti271V → G in AAC14554 (PubMed:9530866).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97336 Genomic DNA Translation: CAB10240.1
AL161539 Genomic DNA Translation: CAB78503.1
CP002687 Genomic DNA No translation available.
U97222 Genomic DNA Translation: AAC50029.1
AF039378 Genomic DNA Translation: AAC14554.1
PIRiF71408

Similar proteinsi

Entry informationi

Entry nameiDRL24_ARATH
AccessioniPrimary (citable) accession number: O23317
Secondary accession number(s): O64972, O82101
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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