UniProtKB - O23247 (SYRM_ARATH)
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Protein
Arginine--tRNA ligase, chloroplastic/mitochondrial
Gene
EMB1027
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.By similarity
Catalytic activityi
ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).Curated
GO - Molecular functioni
- arginine-tRNA ligase activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- arginyl-tRNA aminoacylation Source: GO_Central
- embryo development ending in seed dormancy Source: TAIR
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligase, chloroplastic/mitochondrialCurated (EC:6.1.1.19Curated)Alternative name(s): Arginyl-tRNA synthetaseCurated Short name: ArgRSCurated Protein EMBRYO DEFECTIVE 10271 Publication |
Gene namesi | Name:EMB10271 Publication Ordered Locus Names:At4g26300Imported ORF Names:T25K17.110Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G26300. |
TAIRi | locus:2136794. AT4G26300. |
Pathology & Biotechi
Disruption phenotypei
Embryo defective. Developmental arrest of the embryo at the globular stage.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 53 | Chloroplast and mitochondrionCombined sourcesAdd BLAST | 53 | |
ChainiPRO_0000433552 | 54 – 642 | Arginine--tRNA ligase, chloroplastic/mitochondrialCuratedAdd BLAST | 589 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 54 | N-acetylalanineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | O23247. |
PTM databases
iPTMneti | O23247. |
Expressioni
Gene expression databases
ExpressionAtlasi | O23247. baseline and differential. |
Genevisiblei | O23247. AT. |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 190 – 201 | "HIGH" regionCuratedAdd BLAST | 12 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG4426. Eukaryota. COG0018. LUCA. |
HOGENOMi | HOG000247212. |
InParanoidi | O23247. |
KOi | K01887. |
OMAi | NKPLHLG. |
OrthoDBi | EOG09360567. |
PhylomeDBi | O23247. |
Family and domain databases
CDDi | cd00671. ArgRS_core. 1 hit. |
Gene3Di | 3.30.1360.70. 1 hit. 3.40.50.620. 1 hit. |
HAMAPi | MF_00123. Arg_tRNA_synth. 1 hit. |
InterProi | View protein in InterPro IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. IPR035684. ArgRS_core. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_Ia_anticodon-bd. |
PANTHERi | PTHR11956. PTHR11956. 1 hit. |
Pfami | View protein in Pfam PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. |
PRINTSi | PR01038. TRNASYNTHARG. |
SMARTi | View protein in SMART SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. |
SUPFAMi | SSF47323. SSF47323. 1 hit. SSF55190. SSF55190. 1 hit. |
TIGRFAMsi | TIGR00456. argS. 1 hit. |
PROSITEi | View protein in PROSITE PS00178. AA_TRNA_LIGASE_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O23247-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFIFPKDENR RETLTTKLRF SADHLTFTTV TEKLRATAWR FAFSSRAKSV
60 70 80 90 100
VAMAANEEFT GNLKRQLAKL FDVSLKLTVP DEPSVEPLVA ASALGKFGDY
110 120 130 140 150
QCNNAMGLWS IIKGKGTQFK GPPAVGQALV KSLPTSEMVE SCSVAGPGFI
160 170 180 190 200
NVVLSAKWMA KSIENMLIDG VDTWAPTLSV KRAVVDFSSP NIAKEMHVGH
210 220 230 240 250
LRSTIIGDTL ARMLEYSHVE VLRRNHVGDW GTQFGMLIEY LFEKFPDTDS
260 270 280 290 300
VTETAIGDLQ VFYKASKHKF DLDEAFKEKA QQAVVRLQGG DPVYRKAWAK
310 320 330 340 350
ICDISRTEFA KVYQRLRVEL EEKGESFYNP HIAKVIEELN SKGLVEESEG
360 370 380 390 400
ARVIFLEGFD IPLMVVKSDG GFNYASTDLT ALWYRLNEEK AEWIIYVTDV
410 420 430 440 450
GQQQHFNMFF KAARKAGWLP DNDKTYPRVN HVGFGLVLGE DGKRFRTRAT
460 470 480 490 500
DVVRLVDLLD EAKTRSKLAL IERGKDKEWT PEELDQTAEA VGYGAVKYAD
510 520 530 540 550
LKNNRLTNYT FSFDQMLNDK GNTAVYLLYA HARICSIIRK SGKDIDELKK
560 570 580 590 600
TGKLALDHAD ERALGLHLLR FAETVEEACT NLLPSVLCEY LYNLSEHFTR
610 620 630 640
FYSNCQVNGS PEETSRLLLC EATAIVMRKC FHLLGITPVY KI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z98760 Genomic DNA. Translation: CAB11468.1. AL049171 Genomic DNA. Translation: CAB38959.1. AL161565 Genomic DNA. Translation: CAB79485.1. CP002687 Genomic DNA. Translation: AEE85182.1. |
PIRi | T06014. |
RefSeqi | NP_194360.1. NM_118763.3. |
UniGenei | At.42946. At.75603. |
Genome annotation databases
EnsemblPlantsi | AT4G26300.1; AT4G26300.1; AT4G26300. |
GeneIDi | 828736. |
Gramenei | AT4G26300.1; AT4G26300.1; AT4G26300. |
KEGGi | ath:AT4G26300. |
Similar proteinsi
Entry informationi
Entry namei | SYRM_ARATH | |
Accessioni | O23247Primary (citable) accession number: O23247 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 22, 2015 |
Last sequence update: | January 1, 1998 | |
Last modified: | February 28, 2018 | |
This is version 138 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |