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Protein

Probable ubiquitin-conjugating enzyme E2 17

Gene

UBC17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.By similarity

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ubiquitin-conjugating enzyme E2 17 (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 17
Ubiquitin carrier protein 17
Gene namesi
Name:UBC17
Ordered Locus Names:At4g36410
ORF Names:AP22.89, C7A10.950
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G36410.
TAIRilocus:2115425. AT4G36410.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003451831 – 161Probable ubiquitin-conjugating enzyme E2 17Add BLAST161

Proteomic databases

PaxDbiO23239.
PRIDEiO23239.

Expressioni

Inductioni

By biotic stresses.1 Publication

Gene expression databases

ExpressionAtlasiO23239. baseline and differential.
GenevisibleiO23239. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi15075. 14 interactors.
STRINGi3702.AT4G36410.1.

Structurei

3D structure databases

ProteinModelPortaliO23239.
SMRiO23239.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0427. Eukaryota.
COG5078. LUCA.
HOGENOMiHOG000233453.
InParanoidiO23239.
KOiK10688.
OMAiNCKHGRS.
OrthoDBiEOG09360P07.
PhylomeDBiO23239.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O23239-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSSESTRK GLTKIATNRL QKEFMEWQTN PPSGFKHRVS DNLQRWIIEV
60 70 80 90 100
HGVPGTLYAN ETYQLQVEFP EHYPMEAPQV IFQHPAPLHP HIYSNGHICL
110 120 130 140 150
DVLYDSWSPA MRLSSICLSI LSMLSSSSVK QKPKDNDHYL KNCKHGRSPK
160
ETRWRFHDDK V
Length:161
Mass (Da):18,674
Last modified:January 1, 1998 - v1
Checksum:iC2F62F1FD557FD7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF028340 mRNA. Translation: AAC39326.1.
DQ027031 mRNA. Translation: AAY44857.1.
Z99708 Genomic DNA. Translation: CAB16814.1.
AL161589 Genomic DNA. Translation: CAB80307.1.
CP002687 Genomic DNA. Translation: AEE86653.1.
AY088076 mRNA. Translation: AAM65622.1.
PIRiT52053.
RefSeqiNP_568004.1. NM_119804.2.
UniGeneiAt.24042.

Genome annotation databases

EnsemblPlantsiAT4G36410.1; AT4G36410.1; AT4G36410.
GeneIDi829793.
GrameneiAT4G36410.1; AT4G36410.1; AT4G36410.
KEGGiath:AT4G36410.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiUBC17_ARATH
AccessioniPrimary (citable) accession number: O23239
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: January 1, 1998
Last modified: June 7, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families