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Protein

Probable ubiquitin-conjugating enzyme E2 17

Gene

UBC17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.By similarity

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
R-ATH-983168 Antigen processing: Ubiquitination & Proteasome degradation
UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ubiquitin-conjugating enzyme E2 17 (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 17
Ubiquitin carrier protein 17
Gene namesi
Name:UBC17
Ordered Locus Names:At4g36410
ORF Names:AP22.89, C7A10.950
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G36410
TAIRilocus:2115425 AT4G36410

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003451831 – 161Probable ubiquitin-conjugating enzyme E2 17Add BLAST161

Proteomic databases

PaxDbiO23239
PRIDEiO23239

Expressioni

Inductioni

By biotic stresses.1 Publication

Gene expression databases

ExpressionAtlasiO23239 differential
GenevisibleiO23239 AT

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi15075, 14 interactors
STRINGi3702.AT4G36410.1

Structurei

3D structure databases

ProteinModelPortaliO23239
SMRiO23239
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0427 Eukaryota
COG5078 LUCA
HOGENOMiHOG000233453
InParanoidiO23239
KOiK10688
OMAiNCKHGRS
OrthoDBiEOG09360P07
PhylomeDBiO23239

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

O23239-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSSESTRK GLTKIATNRL QKEFMEWQTN PPSGFKHRVS DNLQRWIIEV
60 70 80 90 100
HGVPGTLYAN ETYQLQVEFP EHYPMEAPQV IFQHPAPLHP HIYSNGHICL
110 120 130 140 150
DVLYDSWSPA MRLSSICLSI LSMLSSSSVK QKPKDNDHYL KNCKHGRSPK
160
ETRWRFHDDK V
Length:161
Mass (Da):18,674
Last modified:January 1, 1998 - v1
Checksum:iC2F62F1FD557FD7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF028340 mRNA Translation: AAC39326.1
DQ027031 mRNA Translation: AAY44857.1
Z99708 Genomic DNA Translation: CAB16814.1
AL161589 Genomic DNA Translation: CAB80307.1
CP002687 Genomic DNA Translation: AEE86653.1
AY088076 mRNA Translation: AAM65622.1
PIRiT52053
RefSeqiNP_568004.1, NM_119804.2
UniGeneiAt.24042

Genome annotation databases

EnsemblPlantsiAT4G36410.1; AT4G36410.1; AT4G36410
GeneIDi829793
GrameneiAT4G36410.1; AT4G36410.1; AT4G36410
KEGGiath:AT4G36410

Similar proteinsi

Entry informationi

Entry nameiUBC17_ARATH
AccessioniPrimary (citable) accession number: O23239
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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