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Protein

Homeobox-leucine zipper protein ATHB-40

Gene

ATHB-40

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi52 – 111HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • response to auxin Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Stress response, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein ATHB-40
Alternative name(s):
HD-ZIP protein ATHB-40
Homeodomain transcription factor ATHB-40
Gene namesi
Name:ATHB-40
Ordered Locus Names:At4g36740
ORF Names:C7A10.620
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G36740.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002578011 – 216Homeobox-leucine zipper protein ATHB-40Add BLAST216

Proteomic databases

PaxDbiO23208.

Expressioni

Tissue specificityi

Expressed in roots, flowers and siliques.1 Publication

Inductioni

By abscisic acid (ABA) and by salt stress.1 Publication

Gene expression databases

GenevisibleiO23208. AT.

Interactioni

Protein-protein interaction databases

BioGridi15108. 2 interactors.
STRINGi3702.AT4G36740.1.

Structurei

3D structure databases

ProteinModelPortaliO23208.
SMRiO23208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni112 – 140Leucine-zipperAdd BLAST29

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000034122.
InParanoidiO23208.
KOiK09338.
OMAiELNFGNE.
OrthoDBiEOG09360OA8.
PhylomeDBiO23208.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR000047. HTH_motif.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00031. HTHREPRESSR.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O23208-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYTVDDQNM AFISQLYPDV YTQIVQPGEV KQPKRRRKKT KGSVASADGG
60 70 80 90 100
NGLFRKRKLT DEQVNMLEMS FGDEHKLESE RKDRLAAELG LDPRQVAVWF
110 120 130 140 150
QNRRARWKNK RLEEEYNKLK NSHDNVVVDK CRLESEVIQL KEQLYDAERE
160 170 180 190 200
IQRLAERVEG GSSNSPISSS VSVEANETPF FGDYKVGDDG DDYDHLFYPV
210
PENSYIDEAE WMSLYI
Length:216
Mass (Da):25,080
Last modified:February 8, 2011 - v3
Checksum:i3847152AB0A4BBF5
GO

Sequence cautioni

The sequence CAB16824 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80340 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti103 – 104RR → LC in BX827896 (PubMed:14993207).Curated2
Sequence conflicti146D → Y in BX827896 (PubMed:14993207).Curated1
Sequence conflicti195H → Y in BX827896 (PubMed:14993207).Curated1
Sequence conflicti207D → A in BX827896 (PubMed:14993207).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA. Translation: CAB16824.1. Sequence problems.
AL161589 Genomic DNA. Translation: CAB80340.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE86696.1.
BX827896 mRNA. No translation available.
PIRiH85433.
RefSeqiNP_195392.2. NM_119838.3.
UniGeneiAt.50404.

Genome annotation databases

EnsemblPlantsiAT4G36740.1; AT4G36740.1; AT4G36740.
GeneIDi829827.
GrameneiAT4G36740.1; AT4G36740.1; AT4G36740.
KEGGiath:AT4G36740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA. Translation: CAB16824.1. Sequence problems.
AL161589 Genomic DNA. Translation: CAB80340.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE86696.1.
BX827896 mRNA. No translation available.
PIRiH85433.
RefSeqiNP_195392.2. NM_119838.3.
UniGeneiAt.50404.

3D structure databases

ProteinModelPortaliO23208.
SMRiO23208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi15108. 2 interactors.
STRINGi3702.AT4G36740.1.

Proteomic databases

PaxDbiO23208.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G36740.1; AT4G36740.1; AT4G36740.
GeneIDi829827.
GrameneiAT4G36740.1; AT4G36740.1; AT4G36740.
KEGGiath:AT4G36740.

Organism-specific databases

TAIRiAT4G36740.

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000034122.
InParanoidiO23208.
KOiK09338.
OMAiELNFGNE.
OrthoDBiEOG09360OA8.
PhylomeDBiO23208.

Miscellaneous databases

PROiO23208.

Gene expression databases

GenevisibleiO23208. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR000047. HTH_motif.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00031. HTHREPRESSR.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATB40_ARATH
AccessioniPrimary (citable) accession number: O23208
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: February 8, 2011
Last modified: November 30, 2016
This is version 116 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.