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Protein

Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2

Gene

At4g36750

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the transfer of electrons from NADH and NADPH to reduce quinone to the hydroquinone state.By similarity

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.By similarity

Cofactori

FMNBy similarityNote: Binds 1 FMN per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei83NADBy similarity1
Binding sitei207FMNBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi81 – 85FMNPROSITE-ProRule annotation5
Nucleotide bindingi183 – 236FMNPROSITE-ProRule annotationAdd BLAST54

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G36750-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2Curated (EC:1.6.5.2By similarity)
Gene namesi
Ordered Locus Names:At4g36750Imported
ORF Names:C7A10.610Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G36750
TAIRilocus:2115405 AT4G36750

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004312851 – 273Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2Add BLAST273

Proteomic databases

PaxDbiO23207
PRIDEiO23207

PTM databases

iPTMnetiO23207
SwissPalmiO23207

Expressioni

Gene expression databases

ExpressionAtlasiO23207 baseline and differential
GenevisibleiO23207 AT

Interactioni

Protein-protein interaction databases

BioGridi15109, 1 interactor
STRINGi3702.AT4G36750.1

Structurei

3D structure databases

ProteinModelPortaliO23207
SMRiO23207
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 263Flavodoxin-likePROSITE-ProRule annotationAdd BLAST189

Sequence similaritiesi

Belongs to the WrbA family.Curated

Phylogenomic databases

eggNOGiKOG3135 Eukaryota
COG0655 LUCA
HOGENOMiHOG000030539
InParanoidiO23207
KOiK03809
OMAiHGSTRKL
OrthoDBiEOG09360Q18
PhylomeDBiO23207

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

O23207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGGGCVPS KKKKPATTGD GPGIDDDNDA TNAPIQIDDD QTTIDGDRTT
60 70 80 90 100
ATNTGGTTTP AITTTAAKIS SPLKIFVVFY SMYGHVESLA KRMKKGVDSV
110 120 130 140 150
EGVEATLYRV PETLSQEVVE QMKAPVKDLE IPEITAAELT AADGFLFGFP
160 170 180 190 200
TRYGCMAAQM KAFFDSTGSL WKEQSLAGKP AGFFVSTGTQ GGGQETTAWT
210 220 230 240 250
AITQLVHHGM LFVPIGYTFG AGMFKMDSIR GGSPYGAGVF AGDGSREATE
260 270
TELALAEHQG NYMAAIVKRL AQP
Length:273
Mass (Da):28,754
Last modified:January 1, 1998 - v1
Checksum:i56DBACF13152DFC2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti55G → A in AAM64959 (Ref. 4) 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA Translation: CAB16805.1
AL161590 Genomic DNA Translation: CAB80341.1
CP002687 Genomic DNA Translation: AEE86697.1
AY087410 mRNA Translation: AAM64959.1
PIRiA85434
RefSeqiNP_195393.1, NM_119839.6
UniGeneiAt.4629

Genome annotation databases

EnsemblPlantsiAT4G36750.1; AT4G36750.1; AT4G36750
GeneIDi829828
GrameneiAT4G36750.1; AT4G36750.1; AT4G36750
KEGGiath:AT4G36750

Similar proteinsi

Entry informationi

Entry nameiFQRL2_ARATH
AccessioniPrimary (citable) accession number: O23207
Secondary accession number(s): Q8LB59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 26, 2014
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health