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Protein

Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2

Gene

At4g36750

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the transfer of electrons from NADH and NADPH to reduce quinone to the hydroquinone state.By similarity

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.By similarity

Cofactori

FMNBy similarityNote: Binds 1 FMN per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei83NADBy similarity1
Binding sitei207FMNBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi81 – 85FMNPROSITE-ProRule annotation5
Nucleotide bindingi183 – 236FMNPROSITE-ProRule annotationAdd BLAST54

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G36750-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2Curated (EC:1.6.5.2By similarity)
Gene namesi
Ordered Locus Names:At4g36750Imported
ORF Names:C7A10.610Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G36750.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004312851 – 273Probable NAD(P)H dehydrogenase (quinone) FQR1-like 2Add BLAST273

Proteomic databases

PaxDbiO23207.
PRIDEiO23207.

PTM databases

iPTMnetiO23207.
SwissPalmiO23207.

Expressioni

Gene expression databases

GenevisibleiO23207. AT.

Interactioni

Protein-protein interaction databases

BioGridi15109. 1 interactor.
STRINGi3702.AT4G36750.1.

Structurei

3D structure databases

ProteinModelPortaliO23207.
SMRiO23207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 263Flavodoxin-likePROSITE-ProRule annotationAdd BLAST189

Sequence similaritiesi

Belongs to the WrbA family.Curated
Contains 1 flavodoxin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3135. Eukaryota.
COG0655. LUCA.
HOGENOMiHOG000030539.
InParanoidiO23207.
KOiK03809.
OMAiMMMPLLH.
OrthoDBiEOG09360Q18.
PhylomeDBiO23207.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_dom.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O23207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGGGCVPS KKKKPATTGD GPGIDDDNDA TNAPIQIDDD QTTIDGDRTT
60 70 80 90 100
ATNTGGTTTP AITTTAAKIS SPLKIFVVFY SMYGHVESLA KRMKKGVDSV
110 120 130 140 150
EGVEATLYRV PETLSQEVVE QMKAPVKDLE IPEITAAELT AADGFLFGFP
160 170 180 190 200
TRYGCMAAQM KAFFDSTGSL WKEQSLAGKP AGFFVSTGTQ GGGQETTAWT
210 220 230 240 250
AITQLVHHGM LFVPIGYTFG AGMFKMDSIR GGSPYGAGVF AGDGSREATE
260 270
TELALAEHQG NYMAAIVKRL AQP
Length:273
Mass (Da):28,754
Last modified:January 1, 1998 - v1
Checksum:i56DBACF13152DFC2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti55G → A in AAM64959 (Ref. 4) 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA. Translation: CAB16805.1.
AL161590 Genomic DNA. Translation: CAB80341.1.
CP002687 Genomic DNA. Translation: AEE86697.1.
AY087410 mRNA. Translation: AAM64959.1.
PIRiA85434.
RefSeqiNP_195393.1. NM_119839.6.
UniGeneiAt.4629.

Genome annotation databases

EnsemblPlantsiAT4G36750.1; AT4G36750.1; AT4G36750.
GeneIDi829828.
GrameneiAT4G36750.1; AT4G36750.1; AT4G36750.
KEGGiath:AT4G36750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA. Translation: CAB16805.1.
AL161590 Genomic DNA. Translation: CAB80341.1.
CP002687 Genomic DNA. Translation: AEE86697.1.
AY087410 mRNA. Translation: AAM64959.1.
PIRiA85434.
RefSeqiNP_195393.1. NM_119839.6.
UniGeneiAt.4629.

3D structure databases

ProteinModelPortaliO23207.
SMRiO23207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi15109. 1 interactor.
STRINGi3702.AT4G36750.1.

PTM databases

iPTMnetiO23207.
SwissPalmiO23207.

Proteomic databases

PaxDbiO23207.
PRIDEiO23207.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G36750.1; AT4G36750.1; AT4G36750.
GeneIDi829828.
GrameneiAT4G36750.1; AT4G36750.1; AT4G36750.
KEGGiath:AT4G36750.

Organism-specific databases

TAIRiAT4G36750.

Phylogenomic databases

eggNOGiKOG3135. Eukaryota.
COG0655. LUCA.
HOGENOMiHOG000030539.
InParanoidiO23207.
KOiK03809.
OMAiMMMPLLH.
OrthoDBiEOG09360Q18.
PhylomeDBiO23207.

Enzyme and pathway databases

BioCyciARA:AT4G36750-MONOMER.

Miscellaneous databases

PROiO23207.

Gene expression databases

GenevisibleiO23207. AT.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_dom.
IPR010089. Flavoprotein_WrbA.
IPR005025. FMN_Rdtase-like.
[Graphical view]
PfamiPF03358. FMN_red. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFQRL2_ARATH
AccessioniPrimary (citable) accession number: O23207
Secondary accession number(s): Q8LB59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 26, 2014
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.