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O23141

- SPE2_ARATH

UniProt

O23141 - SPE2_ARATH

Protein

Arginine decarboxylase 2

Gene

SPE2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 123 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-arginine = agmatine + CO2.

    Cofactori

    Pyridoxal phosphate.
    Magnesium.

    Pathwayi

    GO - Molecular functioni

    1. arginine decarboxylase activity Source: TAIR

    GO - Biological processi

    1. arginine catabolic process Source: InterPro
    2. polyamine biosynthetic process Source: TAIR
    3. putrescine biosynthetic process Source: TAIR
    4. response to abscisic acid Source: TAIR
    5. response to cold Source: TAIR
    6. response to jasmonic acid Source: TAIR
    7. response to karrikin Source: TAIR
    8. response to osmotic stress Source: TAIR
    9. response to oxidative stress Source: TAIR
    10. response to salt stress Source: TAIR
    11. response to wounding Source: TAIR
    12. seed development Source: TAIR
    13. spermidine biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Putrescine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Magnesium, Pyridoxal phosphate

    Enzyme and pathway databases

    BioCyciARA:AT4G34710-MONOMER.
    ARA:GQT-1021-MONOMER.
    UniPathwayiUPA00186; UER00284.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Arginine decarboxylase 2 (EC:4.1.1.19)
    Short name:
    ADC 2
    Short name:
    ARGDC 2
    Alternative name(s):
    ADC-N
    Gene namesi
    Name:SPE2
    Ordered Locus Names:At4g34710
    ORF Names:T4L20.290
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G34710.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 711711Arginine decarboxylase 2PRO_0000149947Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei147 – 1471N6-(pyridoxal phosphate)lysineBy similarity

    Proteomic databases

    PaxDbiO23141.
    PRIDEiO23141.

    Expressioni

    Gene expression databases

    ArrayExpressiO23141.
    GenevestigatoriO23141.

    Interactioni

    Protein-protein interaction databases

    BioGridi14905. 1 interaction.
    IntActiO23141. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliO23141.
    SMRiO23141. Positions 51-640.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni331 – 34111Substrate-bindingBy similarityAdd
    BLAST

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1166.
    HOGENOMiHOG000029191.
    InParanoidiO23141.
    KOiK01583.
    OMAiDSEDMVE.
    PhylomeDBiO23141.

    Family and domain databases

    Gene3Di3.20.20.10. 1 hit.
    InterProiIPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSiPR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMiSSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR01273. speA. 1 hit.
    PROSITEiPS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O23141-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPALACVDTS FVPPAYAFSD TAGDVFIPAS SPTSAAVVVD RWSPSLSSSL    50
    YRIDGWGAPY FIANSSGNIS VRPHGSETLP HQDIDLLKIV KKVTGPKSSG 100
    GLGLQLPLIV RFPDVLKNRL ECLQSAFDYA IKSQGYDSHY QGVYPVKCNQ 150
    DRFVVEDIVK FGSSFRFGLE AGSKPEILLA MSCLCKGSPD AFLVCNGFKD 200
    AEYISLALLG RKLALNTVIV LEQEEELDLV IELSQKMNVR PVIGLRAKLR 250
    TKHSGHFGST SGEKGKFGLT TTQIVRVVRK LRQSGMLDCL QLLHFHIGSQ 300
    IPSTSLLSDG VAEAAQLYCE LVRLGAHMKV IDIGGGLGID YDGSKSGESD 350
    LSVAYSLEEY AEAVVASVRV VCDRSSVKHP VICSESGRAI VSHHSVLIFE 400
    AVSADKPMVH QATPGDIQFL LEGNEEARAN YEDLYAAVMR GDHESCLLYV 450
    DQLKQRCVEG FKEGVLSIEQ LASVDGLCEW VLKAIGASDP VHTYNINLSV 500
    FTSIPDLWGI DQLFPIVPIH KLDQRPGARG ILSDLTCDSD GKINKFIGGE 550
    SSLPLHELDK NGSGGRYFLG MFLGGAYEEA LGGVHNLFGG PSVVRVSQSD 600
    GPHSFAVTRA VPGQSSADVL RAMQHEPELM FQTLKHRAEE MMHTKGGSEG 650
    ENEEEEEDDE FNNVAASLDR SFHNMPYLAT EQASPSNSLS AAISNLGFYY 700
    CDEDVYDYIS A 711
    Length:711
    Mass (Da):77,219
    Last modified:January 1, 1998 - v1
    Checksum:i8E003877173DEEE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF009647 mRNA. Translation: AAB72179.1.
    AL023094 Genomic DNA. Translation: CAA18850.1.
    AL161586 Genomic DNA. Translation: CAB80188.1.
    CP002687 Genomic DNA. Translation: AEE86413.1.
    CP002687 Genomic DNA. Translation: AEE86414.1.
    AY039581 mRNA. Translation: AAK62636.1.
    AY093982 mRNA. Translation: AAM16243.1.
    PIRiT05291.
    RefSeqiNP_195197.1. NM_119637.2.
    NP_974684.1. NM_202955.1.
    UniGeneiAt.2313.
    At.43941.

    Genome annotation databases

    EnsemblPlantsiAT4G34710.1; AT4G34710.1; AT4G34710.
    AT4G34710.2; AT4G34710.2; AT4G34710.
    GeneIDi829623.
    KEGGiath:AT4G34710.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF009647 mRNA. Translation: AAB72179.1 .
    AL023094 Genomic DNA. Translation: CAA18850.1 .
    AL161586 Genomic DNA. Translation: CAB80188.1 .
    CP002687 Genomic DNA. Translation: AEE86413.1 .
    CP002687 Genomic DNA. Translation: AEE86414.1 .
    AY039581 mRNA. Translation: AAK62636.1 .
    AY093982 mRNA. Translation: AAM16243.1 .
    PIRi T05291.
    RefSeqi NP_195197.1. NM_119637.2.
    NP_974684.1. NM_202955.1.
    UniGenei At.2313.
    At.43941.

    3D structure databases

    ProteinModelPortali O23141.
    SMRi O23141. Positions 51-640.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 14905. 1 interaction.
    IntActi O23141. 1 interaction.

    Proteomic databases

    PaxDbi O23141.
    PRIDEi O23141.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G34710.1 ; AT4G34710.1 ; AT4G34710 .
    AT4G34710.2 ; AT4G34710.2 ; AT4G34710 .
    GeneIDi 829623.
    KEGGi ath:AT4G34710.

    Organism-specific databases

    TAIRi AT4G34710.

    Phylogenomic databases

    eggNOGi COG1166.
    HOGENOMi HOG000029191.
    InParanoidi O23141.
    KOi K01583.
    OMAi DSEDMVE.
    PhylomeDBi O23141.

    Enzyme and pathway databases

    UniPathwayi UPA00186 ; UER00284 .
    BioCyci ARA:AT4G34710-MONOMER.
    ARA:GQT-1021-MONOMER.

    Gene expression databases

    ArrayExpressi O23141.
    Genevestigatori O23141.

    Family and domain databases

    Gene3Di 3.20.20.10. 1 hit.
    InterProi IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSi PR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMi SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR01273. speA. 1 hit.
    PROSITEi PS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of a second arginine decarboxylase cDNA from Arabidopsis."
      Watson M.B., Yu W., Galloway G., Malmberg R.L.
      Plant Gene Register PGR97-114
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Columbia.
    2. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiSPE2_ARATH
    AccessioniPrimary (citable) accession number: O23141
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 123 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3