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O23141 (SPE2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 122. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine decarboxylase 2

Short name=ADC 2
Short name=ARGDC 2
EC=4.1.1.19
Alternative name(s):
ADC-N
Gene names
Name:SPE2
Ordered Locus Names:At4g34710
ORF Names:T4L20.290
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length711 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2.

Cofactor

Pyridoxal phosphate.

Magnesium.

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 711711Arginine decarboxylase 2
PRO_0000149947

Regions

Region331 – 34111Substrate-binding By similarity

Amino acid modifications

Modified residue1471N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
O23141 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 8E003877173DEEE5

FASTA71177,219
        10         20         30         40         50         60 
MPALACVDTS FVPPAYAFSD TAGDVFIPAS SPTSAAVVVD RWSPSLSSSL YRIDGWGAPY 

        70         80         90        100        110        120 
FIANSSGNIS VRPHGSETLP HQDIDLLKIV KKVTGPKSSG GLGLQLPLIV RFPDVLKNRL 

       130        140        150        160        170        180 
ECLQSAFDYA IKSQGYDSHY QGVYPVKCNQ DRFVVEDIVK FGSSFRFGLE AGSKPEILLA 

       190        200        210        220        230        240 
MSCLCKGSPD AFLVCNGFKD AEYISLALLG RKLALNTVIV LEQEEELDLV IELSQKMNVR 

       250        260        270        280        290        300 
PVIGLRAKLR TKHSGHFGST SGEKGKFGLT TTQIVRVVRK LRQSGMLDCL QLLHFHIGSQ 

       310        320        330        340        350        360 
IPSTSLLSDG VAEAAQLYCE LVRLGAHMKV IDIGGGLGID YDGSKSGESD LSVAYSLEEY 

       370        380        390        400        410        420 
AEAVVASVRV VCDRSSVKHP VICSESGRAI VSHHSVLIFE AVSADKPMVH QATPGDIQFL 

       430        440        450        460        470        480 
LEGNEEARAN YEDLYAAVMR GDHESCLLYV DQLKQRCVEG FKEGVLSIEQ LASVDGLCEW 

       490        500        510        520        530        540 
VLKAIGASDP VHTYNINLSV FTSIPDLWGI DQLFPIVPIH KLDQRPGARG ILSDLTCDSD 

       550        560        570        580        590        600 
GKINKFIGGE SSLPLHELDK NGSGGRYFLG MFLGGAYEEA LGGVHNLFGG PSVVRVSQSD 

       610        620        630        640        650        660 
GPHSFAVTRA VPGQSSADVL RAMQHEPELM FQTLKHRAEE MMHTKGGSEG ENEEEEEDDE 

       670        680        690        700        710 
FNNVAASLDR SFHNMPYLAT EQASPSNSLS AAISNLGFYY CDEDVYDYIS A 

« Hide

References

« Hide 'large scale' references
[1]"Isolation and characterization of a second arginine decarboxylase cDNA from Arabidopsis."
Watson M.B., Yu W., Galloway G., Malmberg R.L.
Plant Gene Register PGR97-114
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF009647 mRNA. Translation: AAB72179.1.
AL023094 Genomic DNA. Translation: CAA18850.1.
AL161586 Genomic DNA. Translation: CAB80188.1.
CP002687 Genomic DNA. Translation: AEE86413.1.
CP002687 Genomic DNA. Translation: AEE86414.1.
AY039581 mRNA. Translation: AAK62636.1.
AY093982 mRNA. Translation: AAM16243.1.
PIRT05291.
RefSeqNP_195197.1. NM_119637.2.
NP_974684.1. NM_202955.1.
UniGeneAt.2313.
At.43941.

3D structure databases

ProteinModelPortalO23141.
SMRO23141. Positions 51-640.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid14905. 1 interaction.
IntActO23141. 1 interaction.

Proteomic databases

PaxDbO23141.
PRIDEO23141.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G34710.1; AT4G34710.1; AT4G34710.
AT4G34710.2; AT4G34710.2; AT4G34710.
GeneID829623.
KEGGath:AT4G34710.

Organism-specific databases

TAIRAT4G34710.

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
InParanoidO23141.
KOK01583.
OMADSEDMVE.
PhylomeDBO23141.

Enzyme and pathway databases

BioCycARA:AT4G34710-MONOMER.
ARA:GQT-1021-MONOMER.
UniPathwayUPA00186; UER00284.

Gene expression databases

ArrayExpressO23141.
GenevestigatorO23141.

Family and domain databases

Gene3D3.20.20.10. 1 hit.
InterProIPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPE2_ARATH
AccessionPrimary (citable) accession number: O23141
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: June 11, 2014
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names