Reviewed,
UniProtKB/Swiss-Prot O23138 (CYC2_ARATH)
Last modified
November 24, 2009.
Version 90.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Probable cytochrome c At1g22840 | ||||
| Gene names |
| ||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||
| Taxonomic identifier | 3702 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 114 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain By similarity. |
| Subcellular location | |
| Post-translational modification | Binds 1 heme group per subunit By similarity. |
| Sequence similarities | Belongs to the cytochrome c family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Mitochondrion |
| Coding sequence diversity | Alternative splicing |
| Ligand | Heme Iron Metal-binding |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cell proliferation Traceable author statement. Source: TAIR electron transport chainInferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membraneInferred from direct assay. Source: TAIR respiratory chainInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | electron carrier activity Inferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Alternative products
| This entry describes 1 isoform produced by alternative splicing. [Select] Note: A number of isoforms are produced. According to EST sequences. | ||||||
| Isoform 1 (identifier: O23138-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 114 | 114 | Probable cytochrome c At1g22840 | PRO_0000108285 | |||||
Sites | |||||||||
| Metal binding | 27 | 1 | Iron (heme axial ligand) By similarity | ||||||
| Metal binding | 89 | 1 | Iron (heme axial ligand) By similarity | ||||||
| Binding site | 23 | 1 | Heme (covalent) By similarity | ||||||
| Binding site | 26 | 1 | Heme (covalent) By similarity | ||||||
Sequences
References
| [1] | "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. Davis R.W.Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [3] | "Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [4] | "Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins." Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J., Millar A.H. Plant Cell 16:241-256(2004) [PubMed: 14671022] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AF000657 Genomic DNA. Translation: AAB72175.1. AY062853 mRNA. Translation: AAL32931.1. AY114580 mRNA. Translation: AAM47899.1. AY087108 mRNA. Translation: AAM64666.1. | |
| IPI | IPI00538949. |
| PIR | C86362. |
| RefSeq | NP_173697.1. |
| UniGene | At.48220 |
3D structure databases | |
| SMR | O23138. Positions 2-112. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | O23138. 2 interactions. |
| STRING | O23138. |
Proteomic databases | |
| PRIDE | O23138. |
| ProMEX | O23138. |
Genome annotation databases | |
| GeneID | 838889. |
| GenomeReviews | Gene locus AT1G22840 in contig CT485782_GR. |
| NMPDR | fig|3702.1.peg.2653. |
Organism-specific databases | |
| GeneFarm | 1711. 128. |
| TAIR | At1g22840. |
Phylogenomic databases | |
| OMA | ANLKEWL |
Gene expression databases | |
| ArrayExpress | O23138. |
| Genevestigator | O23138. |
| GermOnline | AT1G22840. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR002327. Cyt_c_1A/1B. IPR003088. Cyt_c_I. IPR009056. Cyt_c_monohaem. [Graphical view] |
| Gene3D | G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit. |
| PANTHER | PTHR11961. Cyt_CIAB. 1 hit. |
| Pfam | PF00034. Cytochrom_C. 1 hit. [Graphical view] |
| PRINTS | PR00604. CYTCHRMECIAB. |
| PROSITE | PS51007. CYTC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CYC2_ARATH | ||||||||
| Accession | Primary (citable) accession number: O23138 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| Protein Spotlight Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


