O23049 (RK6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6, chloroplastic

Alternative name(s):
Protein EMBRYO DEFECTIVE 2394

Gene names

Name:	RPL6
Synonyms:	EMB2394
Ordered Locus Names:	At1g05190
ORF Names:	YUP8H12.20

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein binds directly to 23S ribosomal RNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center By similarity.
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Subcellular location	Plastid › chloroplast By similarity.
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	chloroplast envelope Inferred from direct assay. Source: TAIR chloroplast stroma Inferred from direct assay. Source: TAIR membrane Inferred from direct assay. Source: TAIR ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 41	41	Chloroplast By similarity
	Chain	42 – 223	182	50S ribosomal protein L6, chloroplastic		PRO_0000249858

Sequences

	Sequence		Length	Mass (Da)
	O23049 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: C5F8176ED59F84B3	FASTA	223	24,706
	10 20 30 40 50 60 MASSLVSSFQ PRSAFLGDRN VFKVSSTPFA QVGYSSKTIE CKESRIGKQP IAVPSNVTIA 70 80 90 100 110 120 LEGQDLKVKG PLGELALTYP REVELTKEES GFLRVKKTVE TRRANQMHGL FRTLTDNMVV 130 140 150 160 170 180 GVSKGFEKKL ILVGVGYRAT VDGKELVLNL GFSHPVKMQI PDSLKVKVEE NTRITVSGYD 190 200 210 220 KSEIGQFAAT VRKWRPPEPY KGKGVKYSDE IVRRKEGKAG KKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AC000098 Genomic DNA. Translation: AAB71459.1.
CP002684 Genomic DNA. Translation: AEE27802.1.
AY040077 mRNA. Translation: AAK64135.1.
AF360265 mRNA. Translation: AAK25975.1.
AY085715 mRNA. Translation: AAM62933.1.

IPI

IPI00527924.

PIR

C86186.

RefSeq

NP_172011.1. NM_100397.2.

UniGene

At.24632.
At.68070.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3BBO	electron microscopy	9.40	I	1-223	[»]

ProteinModelPortal

O23049.

SMR

O23049. Positions 42-223.

ModBase

Search...

Protein-protein interaction databases

STRING

O23049.

Proteomic databases

PRIDE

O23049.

ProMEX

O23049.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblPlants

AT1G05190.1; AT1G05190.1; AT1G05190.

GeneID

839273.

GenomeReviews

Gene locus AT1G05190 in contig CT485782_GR.

KEGG

ath:AT1G05190.

NMPDR

fig|3702.1.peg.673.

Organism-specific databases

GeneFarm

69.

TAIR

At1g05190.

Phylogenomic databases

eggNOG

KOG3254.

GeneTree

EPGT00050000014568.

HOGENOM

HBG606796.

InParanoid

O23049.

OMA

ALINNMV.

PhylomeDB

O23049.

ProtClustDB

CLSN2681987.

Gene expression databases

ArrayExpress

O23049.

Genevestigator

O23049.

GermOnline

AT1G05190. Arabidopsis thaliana.

Family and domain databases

InterPro

IPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR019906. Ribosomal_L6_bac-type.
IPR002358. Ribosomal_L6_CS.
[Graphical view]

Gene3D

G3DSA:3.90.930.12. Ribosomal_L6. 2 hits.

KO

K02933.

PANTHER

PTHR11655. Ribosomal_L6. 1 hit.

Pfam

PF00347. Ribosomal_L6. 2 hits.
[Graphical view]

PIRSF

PIRSF002162. Ribosomal_L6. 1 hit.

PRINTS

PR00059. RIBOSOMALL6.

SUPFAM

SSF56053. Ribosomal_L6. 2 hits.

TIGRFAMs

TIGR03654. L6_bact. 1 hit.

PROSITE

PS00525. RIBOSOMAL_L6_1. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RK6_ARATH

Accession

Primary (citable) accession number: O23049

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2006
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program