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Protein

Expansin-A8

Gene

EXPA8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).By similarity

GO - Biological processi

  • plant-type cell wall organization Source: InterPro
  • syncytium formation Source: TAIR

Keywordsi

Biological processCell wall biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Expansin-A8
Short name:
AtEXPA8
Alternative name(s):
Alpha-expansin-8
Short name:
At-EXP8
Short name:
AtEx8
Ath-ExpAlpha-1.11
Gene namesi
Name:EXPA8
Synonyms:EXP8
Ordered Locus Names:At2g40610
ORF Names:T2P4.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G40610
TAIRilocus:2061918 AT2G40610

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000000868926 – 253Expansin-A8Add BLAST228

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi51 ↔ 79PROSITE-ProRule annotation
Disulfide bondi82 ↔ 155PROSITE-ProRule annotation
Disulfide bondi87 ↔ 94PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiO22874
PRIDEiO22874

Expressioni

Gene expression databases

ExpressionAtlasiO22874 baseline and differential
GenevisibleiO22874 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G40610.1

Structurei

3D structure databases

ProteinModelPortaliO22874
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 160Expansin-like EG45PROSITE-ProRule annotationAdd BLAST113
Domaini170 – 250Expansin-like CBDPROSITE-ProRule annotationAdd BLAST81

Sequence similaritiesi

Belongs to the expansin family. Expansin A subfamily.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IG2H Eukaryota
ENOG410YCRV LUCA
HOGENOMiHOG000220793
InParanoidiO22874
OMAiPGLSNDN
OrthoDBiEOG09360L23
PhylomeDBiO22874

Family and domain databases

Gene3Di2.40.40.10, 1 hit
2.60.40.760, 1 hit
InterProiView protein in InterPro
IPR007118 Expan_Lol_pI
IPR002963 Expansin
IPR007112 Expansin/allergen_DPBB_dom
IPR007117 Expansin_CBD
IPR036749 Expansin_CBD_sf
IPR009009 RlpA-like_DPBB
IPR036908 RlpA-like_sf
PfamiView protein in Pfam
PF03330 DPBB_1, 1 hit
PF01357 Pollen_allerg_1, 1 hit
PRINTSiPR01226 EXPANSIN
PR01225 EXPANSNFAMLY
SMARTiView protein in SMART
SM00837 DPBB_1, 1 hit
SUPFAMiSSF49590 SSF49590, 1 hit
SSF50685 SSF50685, 1 hit
PROSITEiView protein in PROSITE
PS50843 EXPANSIN_CBD, 1 hit
PS50842 EXPANSIN_EG45, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O22874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTPSYLKYS IISIISVLFL QGTHGDDGGW QGGHATFYGG EDASGTMGGA
60 70 80 90 100
CGYGNLYGQG YGTNTAALST ALFNNGLTCG ACYEMKCNDD PRWCLGSTIT
110 120 130 140 150
VTATNFCPPN PGLSNDNGGW CNPPLQHFDL AEPAFLQIAQ YRAGIVPVSF
160 170 180 190 200
RRVPCMKKGG IRFTINGHSY FNLVLISNVG GAGDVHAVSI KGSKTQSWQA
210 220 230 240 250
MSRNWGQNWQ SNSYMNDQSL SFQVTTSDGR TLVSNDVAPS NWQFGQTYQG

GQF
Length:253
Mass (Da):27,260
Last modified:January 1, 1998 - v1
Checksum:i08C42880D523DD8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002336 Genomic DNA Translation: AAB87577.1
CP002685 Genomic DNA Translation: AEC09854.1
AY086770 mRNA Translation: AAM63821.1
PIRiF84831
RefSeqiNP_181593.1, NM_129623.3
UniGeneiAt.42931
At.70279

Genome annotation databases

EnsemblPlantsiAT2G40610.1; AT2G40610.1; AT2G40610
GeneIDi818656
GrameneiAT2G40610.1; AT2G40610.1; AT2G40610
KEGGiath:AT2G40610

Similar proteinsi

Entry informationi

Entry nameiEXPA8_ARATH
AccessioniPrimary (citable) accession number: O22874
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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