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Protein

Expansin-A8

Gene

EXPA8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).By similarity

GO - Biological processi

  • plant-type cell wall organization Source: InterPro
  • syncytium formation Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Cell wall biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Expansin-A8
Short name:
AtEXPA8
Alternative name(s):
Alpha-expansin-8
Short name:
At-EXP8
Short name:
AtEx8
Ath-ExpAlpha-1.11
Gene namesi
Name:EXPA8
Synonyms:EXP8
Ordered Locus Names:At2g40610
ORF Names:T2P4.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G40610.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 253228Expansin-A8PRO_0000008689Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi51 ↔ 79PROSITE-ProRule annotation
Disulfide bondi82 ↔ 155PROSITE-ProRule annotation
Disulfide bondi87 ↔ 94PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiO22874.
PRIDEiO22874.

Expressioni

Gene expression databases

ExpressionAtlasiO22874. baseline and differential.
GenevisibleiO22874. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G40610.1.

Structurei

3D structure databases

ProteinModelPortaliO22874.
SMRiO22874. Positions 27-248.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 160113Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini170 – 25081Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin A subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IG2H. Eukaryota.
ENOG410YCRV. LUCA.
HOGENOMiHOG000220793.
InParanoidiO22874.
OMAiDDPKWCL.
PhylomeDBiO22874.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O22874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTPSYLKYS IISIISVLFL QGTHGDDGGW QGGHATFYGG EDASGTMGGA
60 70 80 90 100
CGYGNLYGQG YGTNTAALST ALFNNGLTCG ACYEMKCNDD PRWCLGSTIT
110 120 130 140 150
VTATNFCPPN PGLSNDNGGW CNPPLQHFDL AEPAFLQIAQ YRAGIVPVSF
160 170 180 190 200
RRVPCMKKGG IRFTINGHSY FNLVLISNVG GAGDVHAVSI KGSKTQSWQA
210 220 230 240 250
MSRNWGQNWQ SNSYMNDQSL SFQVTTSDGR TLVSNDVAPS NWQFGQTYQG

GQF
Length:253
Mass (Da):27,260
Last modified:January 1, 1998 - v1
Checksum:i08C42880D523DD8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002336 Genomic DNA. Translation: AAB87577.1.
CP002685 Genomic DNA. Translation: AEC09854.1.
AY086770 mRNA. Translation: AAM63821.1.
PIRiF84831.
RefSeqiNP_181593.1. NM_129623.2.
UniGeneiAt.42931.
At.70279.

Genome annotation databases

EnsemblPlantsiAT2G40610.1; AT2G40610.1; AT2G40610.
GeneIDi818656.
GrameneiAT2G40610.1; AT2G40610.1; AT2G40610.
KEGGiath:AT2G40610.

Cross-referencesi

Web resourcesi

EXPANSIN homepage

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002336 Genomic DNA. Translation: AAB87577.1.
CP002685 Genomic DNA. Translation: AEC09854.1.
AY086770 mRNA. Translation: AAM63821.1.
PIRiF84831.
RefSeqiNP_181593.1. NM_129623.2.
UniGeneiAt.42931.
At.70279.

3D structure databases

ProteinModelPortaliO22874.
SMRiO22874. Positions 27-248.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G40610.1.

Proteomic databases

PaxDbiO22874.
PRIDEiO22874.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G40610.1; AT2G40610.1; AT2G40610.
GeneIDi818656.
GrameneiAT2G40610.1; AT2G40610.1; AT2G40610.
KEGGiath:AT2G40610.

Organism-specific databases

TAIRiAT2G40610.

Phylogenomic databases

eggNOGiENOG410IG2H. Eukaryota.
ENOG410YCRV. LUCA.
HOGENOMiHOG000220793.
InParanoidiO22874.
OMAiDDPKWCL.
PhylomeDBiO22874.

Miscellaneous databases

PROiO22874.

Gene expression databases

ExpressionAtlasiO22874. baseline and differential.
GenevisibleiO22874. AT.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. Cited for: NOMENCLATURE.

Entry informationi

Entry nameiEXPA8_ARATH
AccessioniPrimary (citable) accession number: O22874
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: January 1, 1998
Last modified: February 17, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.